{"id":130,"date":"2014-07-30T20:42:44","date_gmt":"2014-07-30T20:42:44","guid":{"rendered":"http:\/\/artsci.case.edu\/skeletal\/?page_id=130"},"modified":"2014-07-30T20:42:44","modified_gmt":"2014-07-30T20:42:44","slug":"lennon","status":"publish","type":"page","link":"https:\/\/artsci.case.edu\/skeletal\/cv\/lennon\/","title":{"rendered":"Donald P. Lennon"},"content":{"rendered":"

EDUCATION<\/h3>\n

Bachelor of Science, 1963, Sociology, John Carroll University, Cleveland, Ohio
\nDoctor of Dental Surgery, 1971, Dentisty, Case Western Reserve University<\/p>\n

EMPLOYMENT HISTORY<\/h3>\n

1963-1965 U.S. Army, Fort Wainwright, Alaska, Motor Officer, Transportation Motor Pool.<\/p>\n

1965-1967 Summit County Juvenile Court, Akron, Ohio, Probation Officer.<\/p>\n

1971-1972 Highland View Hospital, Cleveland, Ohio, Dental Internship.<\/p>\n

1972-1973 Private Dental Practice, Cleveland, Ohio, Associate (of) Drs. Rosewater, D.D.S. and Sperber, D.D.S.<\/p>\n

1973-1979 Private Dental Practice, Cleveland, Ohio, Associate (with) Richard J. Stanco, D.D.S.<\/p>\n

1979-Pres Case Western Reserve University, Cleveland, Ohio, Dept of Biology<\/p>\n

1979-1988 Research Assistant; Laboratory of Dr. Arnold I. Caplan.<\/p>\n

1985-1988 Instructor, Human Anatomy.<\/p>\n

1988-Pres Senior Research Associate; Laboratory of Dr. Arnold I. Caplan;
\nDirector, Cell Culture, Skeletal Research Center<\/p>\n

PUBLICATIONS<\/h3>\n
    \n
  1. Lennon, D.P., Osdoby, P., Carrino, D.A., Vertel, B.M. and Caplan, A.I. (1983): “Isolation and Characterization of Chondrocytes and Non-Chondrocytes From High-Density Chick Limb Bud Cultures. ”\u00a0Journal of Craniofacial Genetics and Developmental Biology. 3<\/em>:235-251.<\/li>\n
  2. Carrino, D.A., Lennon, D.P. and Caplan, A.I. (1983): “Extracellular Matrix and the Maintenance of the Differentiated State: Proteoglycans Synthesized by Replated Chondrocytes and Non-Chondrocytes. “Developmental Biology 99<\/em>:132-144.<\/li>\n
  3. Kujawa, M.J., Lennon, D.P. and Caplan, A.I. (1989): “Growth and Differentiation of Stage 24 Limb Mesenchymal Cells in a Serum-Free Chemically Defined Medium. ”\u00a0Experimental Cell Research 183<\/em>:45-61.<\/li>\n
  4. Carrino, D.A., Kujawa, M.J., Lennon, D.P. and Caplan, A.I. (1989): “Altered Cartilage Proteoglycans Synthesized by Chick Limb Bud Chondrocytes Cultured in Serum-Free Defined Medium. “Experimental Cell Research 183<\/em>:62-71.<\/li>\n
  5. Nakahara, H., Dennis, J.D., Bruder, S.B., Haynesworth, S.E., Lennon, D.P. and Caplan, A.I. (1991): “In<\/em>\u00a0Vitro<\/em>\u00a0Differentiation of Bone and Hypertrophic Cartilage From Periosteal-Derived Cells. “Experimental Cell Research 195<\/em>:492-503.<\/li>\n
  6. Lennon, D.P., Carrino, D.A., Baber, M.A. and Caplan, A.I. (1991): “Generation of a Monoclonal Antibody Against Avian Small Dermatan Sulfate Proteoglycans: Immunolocalization and Tissue Distribution of PG-II (Decorin) in Embryonic Tissues. ”\u00a0Matrix 11<\/em>:412-427.<\/li>\n
  7. Lennon, D.P., Haynesworth, S.E., Young, R.G., Dennis, J.E. and Caplan, A.I. (1995): “A Chemically Defined Medium Supports Proliferation and Maintains Osteochondrogenic Potential of Rat Marrow-Derived Mesenchymal Stem Cells, ”\u00a0Experimental Cell Research 219<\/em>:211-222.<\/li>\n
  8. Saito, T., Dennis, J.E., Lennon, D.P., Young, R.G. and Caplan, A.I. (1996): “Evidence for Fusion and Dystrophin Expression of Mesenchymal Stem Cells Within Myotubes of\u00a0mdx<\/i>\u00a0Mice\u00a0In Vitro<\/i>\u00a0and\u00a0In Vivo, “<\/i>\u00a0Tissue Engineering 1<\/em>:327-344.<\/li>\n
  9. Lennon, D.P., Bruder, S.P., Haynesworth, S.E., Jaiswal, N., and Caplan, A.I. (1996): Human and Animal Mesenchymal Progenitor Cells From Bone Marrow: Selection of Serum for Optimal Proliferation. ”\u00a0In Vitro<\/i>\u00a0Cell and Developmental Biology 32<\/em>:602-611.<\/li>\n
  10. Mann, L.M., Lennon, D.P., and Caplan, A.I. (1996): “Cultured Rat Pulp Cells have the Potential to form Bone, Cartliage, and Dentin\u00a0In Vivo<\/i>\u00a0Biological Mechanisms of Tooth Movement and Craniofacial Adaptation<\/em>, Edited by Z. Davidovittch and L.A. Norton, pages 7-16, Harvard Society for the Advancement of Orthdontics, Boston, MA.<\/li>\n
  11. Boyan, B.D., Caplan, A.I., Heckman, J.D., Lennon, D.P., Ehler, W., and Schwartz, Z. (1999): ” Osteochondral Progenitor Cells in Acute and Chronic Canine Nonunions.”\u00a0Journal of Orthop\u00e6dic Research 17(2)<\/em>: 246-255.<\/li>\n
  12. Nakamura, O., Fink, D.J., Lennon, D.P., Laraia, V.L., Heuer, A.H., and Caplan, A.I. (1999): “Matrix-Directed\u00a0In Vitro<\/i>\u00a0Osteogenesis. ” Bioceramics vol 12, p 249-252, eds H. Ohgushi, G.W. Hastings and T. Yoshikawa (Proceedings of the 12th<\/sup>\u00a0Intl Symposium on Ceramics in Medicine) Nara, Japan 1999; World Scientific Publishing Pte Ltd.<\/li>\n
  13. Lennon, D.P., Haynesworth, S.E., Arm, D., Baber, M.A. and Caplan A.I. (2000): “Dilution of Human Mesenchymal Stem Cells Dermal Fibroblasts and the Effects on In Vitro and In Vivo Osteogenesis.”Developmental Dynamics<\/em>\u00a0219:50-62.<\/li>\n
  14. Lennon, D.P., Edmison, J., and Caplan, A. I. (2000):”Cultivation of Rat Marrow-Derived Mesenchymal Stem Cells in Reduced Oxygen Tension: Effects on\u00a0In Vitro<\/i>\u00a0and\u00a0In Vivo<\/i>Osteochondrogenesis.\u00a0Journal of Cellular Physiology<\/em>\u00a0187:345-355.<\/li>\n
  15. Tallheden, T., Dennis, J.E., Lennon, D.P., Sj\u00f6gren-Jansson, E., and Caplan, A.I. (2003): “Heterogeneity in Multipotency of Human Articular Chondrocytes.\u201d\u00a0Journal of Bone & Joint Surgery 85-A Suppl 2<\/em>:93-100.<\/li>\n
  16. Yamashita, K., Dennis, J.E., Lennon, D.P., Morimoto, H., Kitamura, S., and Caplan, A.I. (2003): “Dental Pulp Cells with Multi-Potential for Differentiation to Odontoblast and Chondroblast\u201d\u00a0Journal of Hard Tissue Biology 12<\/em>[21] (2003):49-55.<\/li>\n
  17. Solchaga, L.A., Welter, J.F., Lennon, D.P., and Caplan, A.I. (2004): “Generation of Pleuripotent Stem Cells and their Differentiation to the Chondrocytic Phenotype\u201d In: Osteoarthritis: Methods in Molecular Medicine, vol. 100: Cartilage and Osteoarthritis, vol 1: 53-67, edited by M. Sabiatini, P. Pastoureau, and F. De Ceuninck, Humana Press, Totawa, NJ.<\/li>\n
  18. Alhadlaq, A., Elisseeff, J., Hong, L., Williams, C., Caplan A.I., Sharma, B., Kopher, R., Tomkoria, S., Lennon, D.P., Lopez, A., Mao, J. (2004): “Adult stem cell driven genesis of human-shaped articular condyle\u201d\u00a0Annals of Biomedical Engineering 32<\/em>:911-923.<\/li>\n
  19. Dean, D., Wolfe, M.S., Ahmad,Y., Totonchi, A., Chen, J. E-K., Fisher, J.P., Cooke, M.N., Rimnac, C.M., Lennon, D.P., Caplan, A.I., Topham, N.S., Mikos, A.G. (2005): “Effect of Transforming Growth Factor b-2 on Marrow-Infused Foam Poly(Propylene Fumarate) Tissue-Engineered Constructs for the Repair of Critical-Size Cranial Defects in Rabbits\u201d,\u00a0Tissue Engineering 11<\/em>[5\/6]: 923-939.<\/li>\n
  20. Lennon, D.P. and Caplan, A.I. (2006): “Mesenchymal Stem Cells for Tissue Engineering\u201d In: Culture of Cells for Tissue Engineering, edited by I. Freshney and G. Vunjak-Novakovic, John Wiley and Sons, Hoboken, NJ.<\/li>\n
  21. Lennon, D.P. and Caplan, A.I. (2006): “Isolation of Human Marrow-derived Mesenchymal Stem Cells\u201d,\u00a0Experimental Hematology, 34<\/em>:1604-1605.<\/li>\n
  22. Lennon, D.P. and Caplan, A.I. (2006): “Isolation of Rat Marrow-derived Mesenchymal Stem Cells\u201d,Experimental Hematology, 34<\/em>:1606-1607.<\/li>\n
  23. Bai, L., Caplan, A.I., Lennon, D.P., Miller, R. (2007): “Mesenchymal Stem Cell Signals Regulate Neural Stem Cell Fate\u201d.\u00a0Neurochemical Research, 32<\/em>:353-362<\/li>\n
  24. Grayson, W.L., Brumirantana, S., Canizzarro, C., Chao, P.G., Lennon, D.P., Caplan, A.I., and Vunjak-Novakovic, G. (2008): “Effects of Initial Seeding Density and Fluid Perfusion Rate on Formation of Tissue-Engineered Bone\u201d,\u00a0Tissue Engineering (In Press)<\/em>.<\/li>\n
  25. da Silva Meirelles L., Sand T.T., Harman R.J., Lennon D.P., and Caplan A.I. (2009): “MSC frequency correlates with blood vessel density in equine adipose tissue.”\u00a0Tissue Eng Part A.<\/em>: 15(2):221-9.PMID: 18847356<\/li>\n
  26. Bai L., Lennon D.P., Eaton V., Maier K., Caplan A.I., Miller S.D., and Miller R.H. (2009): “Human bone marrow-derived mesenchymal stem cells induce Th2-polarized immune response and promote endogenous repair in animal models of multiple sclerosis.”\u00a0Glia 57<\/em>\u00a0(11):1192-203.PMID: 19191336<\/li>\n
  27. Diekman B.O., Rowland C.R., Caplan A.I., Lennon D., and Guilak F. (2009): “Chondrogenesis of adult stem cells from adipose tissue and bone marrow: Induction by growth factors and cartilage derived matrix.”\u00a0Tissue Eng Part A.<\/em>\u00a0[Epub ahead of print] PMID: 19715387<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

    EDUCATION
    \nBachelor of Science, 1963, Sociology, John Carroll University, Cleveland, Ohio
    \nDoctor of Dental Surgery, 1971, Dentisty, Case Western Reserve University
    \nEMPLOYMENT HISTORY
    \n1963-1965 U.S. Army, Fort Wainwright, Alaska, Motor Officer, Transportation Motor Pool.<\/p>\n

    1965-1967 Summit County Juvenile Court, Akron, Ohio, Probation Officer.<\/p>\n

    1971-1972 Highland View Hospital, Cleveland, Ohio, Dental Internship.<\/p>\n

    1972-1973 Private Dental Practice, Cleveland, Ohio, Associate (of) Drs. Rosewater, D.D.S. and Sperber, D.D.S.<\/p>\n

    1973-1979 Private Dental Practice, Cleveland, Ohio, Associate (with) Richard J. Stanco, D.D.S.<\/p>\n

    1979-Pres Case Western Reserve University, Cleveland, Ohio, Dept of Biology<\/p>\n

    1979-1988 Research Assistant;<\/p>\n

    Continue reading… Donald P. Lennon<\/span><\/a><\/p>\n","protected":false},"author":19,"featured_media":0,"parent":125,"menu_order":0,"comment_status":"open","ping_status":"open","template":"","meta":{"spay_email":""},"_links":{"self":[{"href":"https:\/\/artsci.case.edu\/skeletal\/wp-json\/wp\/v2\/pages\/130"}],"collection":[{"href":"https:\/\/artsci.case.edu\/skeletal\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/artsci.case.edu\/skeletal\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/artsci.case.edu\/skeletal\/wp-json\/wp\/v2\/users\/19"}],"replies":[{"embeddable":true,"href":"https:\/\/artsci.case.edu\/skeletal\/wp-json\/wp\/v2\/comments?post=130"}],"version-history":[{"count":1,"href":"https:\/\/artsci.case.edu\/skeletal\/wp-json\/wp\/v2\/pages\/130\/revisions"}],"predecessor-version":[{"id":131,"href":"https:\/\/artsci.case.edu\/skeletal\/wp-json\/wp\/v2\/pages\/130\/revisions\/131"}],"up":[{"embeddable":true,"href":"https:\/\/artsci.case.edu\/skeletal\/wp-json\/wp\/v2\/pages\/125"}],"wp:attachment":[{"href":"https:\/\/artsci.case.edu\/skeletal\/wp-json\/wp\/v2\/media?parent=130"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}