{"id":151,"date":"2014-07-30T21:40:07","date_gmt":"2014-07-30T21:40:07","guid":{"rendered":"http:\/\/artsci.case.edu\/skeletal\/?page_id=151"},"modified":"2019-10-23T20:47:28","modified_gmt":"2019-10-23T20:47:28","slug":"welter","status":"publish","type":"page","link":"https:\/\/artsci.case.edu\/skeletal\/cv\/welter\/","title":{"rendered":"Jean Frederic Welter, M.D., M.Sc., Ph.D."},"content":{"rendered":"<p><strong>Research Associate Professor <\/strong><br \/>\n<strong>Skeletal Research Center, Department of Biology,<\/strong><br \/>\n<strong>Case Western Reserve University<\/strong><br \/>\n<strong>Millis Science Center, Room 114B<\/strong><br \/>\n<strong>2080 Adelbert Road<\/strong><br \/>\n<strong>Cleveland, Ohio 44106-7080<\/strong><br \/>\n<strong>Tel.: (216) 368-1333 (Office), (216) 368-2777 (Lab),<\/strong><br \/>\n<strong>Fax: (216) 368-4077<\/strong><br \/>\n<strong>E-mail: jfw2@cwru.edu<\/strong><\/p>\n<p><strong>October, 2019<\/strong><\/p>\n<h3>Educational Background:<\/h3>\n<table cellspacing=\"10\">\n<tbody>\n<tr>\n<td width=\"15%\">1996<\/td>\n<td width=\"85%\">Ph.D. (Physiology &amp; Biophysics), Case Western Reserve University, Cleveland, OH, U.S.A.<\/td>\n<\/tr>\n<tr>\n<td>1990<\/td>\n<td>M.Sc.\u00a0(Experimental\u00a0Surgery), Dean&#8217;s\u00a0Honors List McGill University, Montr\u00e9al,\u00a0Qu\u00e9bec,\u00a0Canada<\/td>\n<\/tr>\n<tr>\n<td>1984<\/td>\n<td>Permanent ECFMG certificate, Foreign Medical Graduate Examination in the Medical Sciences (F.M.G.E.M.S.)<\/td>\n<\/tr>\n<tr>\n<td>1984<\/td>\n<td>Doktor der gesamten Heilkunde (M.D.), School of Medicine, Leopold\u00a0Franzens\u00a0Universit\u00e4t, Innsbruck,\u00a0Austria<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<h3>Professional Experience:<\/h3>\n<table cellspacing=\"10\">\n<tbody>\n<tr>\n<td width=\"15%\">2016 &#8211;<\/td>\n<td width=\"85%\">Associate Director, Case Center for Multimodal Evaluation of Engineered Cartilage, Case Western Reserve University, Cleveland, OH<\/td>\n<\/tr>\n<tr>\n<td width=\"15%\">2007 &#8211;<\/td>\n<td width=\"85%\">Research Associate Professor, Department of Biology Case\u00a0Western\u00a0Reserve University, Cleveland, OH<\/td>\n<\/tr>\n<tr>\n<td>2012 &#8211;<\/td>\n<td>Research Associate Professor, Center for Regenerative Medicine, School of Medicine, Division of General Medical Sciences, Case Western Reserve University, Cleveland, OH (Secondary Appointment)<\/td>\n<\/tr>\n<tr>\n<td>2004 &#8211; 2007<\/td>\n<td>Senior Research Associate, Skeletal Research Center Case\u00a0Western\u00a0Reserve University, Cleveland, OH<\/td>\n<\/tr>\n<tr>\n<td>1998 &#8211; 2004<\/td>\n<td>Assistant Professor, Department of Orthop\u00e6dics, Case\u00a0Western\u00a0Reserve University, Cleveland, OH<\/td>\n<\/tr>\n<tr>\n<td>1996 &#8211; 1998<\/td>\n<td>Instructor, Department of Orthop\u00e6dics, Case\u00a0Western\u00a0Reserve University, Cleveland, OH<\/td>\n<\/tr>\n<tr>\n<td>1990 &#8211; 1996<\/td>\n<td>Ph.D. Candidate, Department of Physiology &amp; Biophysics, Case Western Reserve University, Cleveland, OH<\/td>\n<\/tr>\n<tr>\n<td>1989 &#8211; 1990<\/td>\n<td>Post-Doctoral Fellow, Department of Orthop\u00e6dics, Case\u00a0Western\u00a0Reserve University, Cleveland, OH<\/td>\n<\/tr>\n<tr>\n<td>1988 &#8211; 1989<\/td>\n<td>PGY-1 Surgery Resident, Surgery Residency\u00a0Program, Case\u00a0Western\u00a0Reserve University, Cleveland, OH<\/td>\n<\/tr>\n<tr>\n<td>1985 &#8211; 1988<\/td>\n<td>Research Fellow, Montreal\u00a0Children&#8217;s\u00a0Hospital Research Institute (Orthop\u00e6dic\u00a0Research\u00a0Laboratory), Montr\u00e9al, PQ, Canada<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<h3>Professional Affiliations:<\/h3>\n<table cellspacing=\"10\">\n<tbody>\n<tr>\n<td width=\"15%\">2010 &#8211; Present<\/td>\n<td width=\"85%\">Tissue Engineering and Regenerative Medicine International Society<\/td>\n<\/tr>\n<tr>\n<td>2008 &#8211; Present<\/td>\n<td>Osteoarthritis Research Society International<\/td>\n<\/tr>\n<tr>\n<td>2007 &#8211; Present<\/td>\n<td>Biomedical Engineering Society<\/td>\n<\/tr>\n<tr>\n<td>2003 &#8211; Present<\/td>\n<td>International Cartilage Repair Society<\/td>\n<\/tr>\n<tr>\n<td>2001 &#8211; Present<\/td>\n<td>American Society for Bone and Mineral Research<\/td>\n<\/tr>\n<tr>\n<td>1998 &#8211; Present<\/td>\n<td>American Society for Biochemistry &amp; Molecular Biology<\/td>\n<\/tr>\n<tr>\n<td>1997 &#8211; 2014<\/td>\n<td>Orthop\u00e6dic Research Society<\/td>\n<\/tr>\n<tr>\n<td>1989 &#8211; Present<\/td>\n<td>American Association for the Advancement of Science<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<h3>Honors and Awards:<\/h3>\n<table cellspacing=\"10\">\n<tbody>\n<tr>\n<td width=\"15%\">2006<\/td>\n<td width=\"85%\">ICRS poster award\u00a0<em>\u201cCum Laude<\/em>\u201d<\/td>\n<\/tr>\n<tr>\n<td>2003, 2005<\/td>\n<td>Arthritis Foundation travel ward<\/td>\n<\/tr>\n<tr>\n<td>1991 &#8211; 1993<\/td>\n<td>Research Fellowship, Cell Physiology Training Program. Department of Physiology &amp; Biophysics, Case Western Reserve University, Cleveland, OH<\/td>\n<\/tr>\n<tr>\n<td>1990<\/td>\n<td>McGill University, Dean&#8217;s Honors List<\/td>\n<\/tr>\n<tr>\n<td>1989 &#8211; 1990<\/td>\n<td>Research Fellowship, NIH Training Program in Musculoskeletal Research. Department\u00a0of\u00a0Orthop\u00e6dics, Case\u00a0Western\u00a0Reserve University, Cleveland, OH<\/td>\n<\/tr>\n<tr>\n<td>1985 &#8211; 1988<\/td>\n<td>Fellow of the McGill University &#8211; Montreal Children&#8217;s Hospital Research Institute<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<h3>Teaching Experience:<\/h3>\n<table cellspacing=\"10\">\n<tbody>\n<tr>\n<td><strong>High school<\/strong><\/td>\n<\/tr>\n<tr>\n<td width=\"15%\">2019<\/td>\n<td width=\"85%\">Cheyenne Jones, Hathaway Brown, student advisor<\/td>\n<\/tr>\n<tr>\n<td>2013<\/td>\n<td>Jake Althans, Gilmour Academy student co-advisor<\/td>\n<\/tr>\n<tr>\n<td>2012<\/td>\n<td>Sarah Abdalian, Gilmour Academy student co-advisor<\/td>\n<\/tr>\n<tr>\n<td><strong>Undergraduate<\/strong><\/td>\n<\/tr>\n<tr>\n<td width=\"15%\">2018 &#8211;<\/td>\n<td width=\"85%\">Kareem Akabashoroun, work study student\/web assistant<\/td>\n<\/tr>\n<tr>\n<td width=\"15%\">2017<\/td>\n<td>Hanna Chan, undergraduate project co-advisor (MAE)<\/td>\n<\/tr>\n<tr>\n<td width=\"15%\">2014-2016<\/td>\n<td>Joe Heebner, undergraduate project co-advisor (MAE)<\/td>\n<\/tr>\n<tr>\n<td width=\"15%\">2013-2016<\/td>\n<td width=\"85%\">Joe Heebner, ENGAGE fellowship sponsor<\/td>\n<\/tr>\n<tr>\n<td>2013<\/td>\n<td>Marine Gu, M.Sc. co-advisor and committee member<\/td>\n<\/tr>\n<tr>\n<td width=\"15%\">2011<\/td>\n<td>Marine Gu, undergraduate senior project co-advisor<\/td>\n<\/tr>\n<tr>\n<td width=\"15%\">2011<\/td>\n<td>Eduardo Arellano, summer laboratory project co-advisor<\/td>\n<\/tr>\n<tr>\n<td width=\"15%\">2010 &#8211; 2011<\/td>\n<td>Marcin Citak, undergraduate senior project co-advisor<\/td>\n<\/tr>\n<tr>\n<td width=\"15%\">2009<\/td>\n<td>Jason Walker, summer undergraduate student<\/td>\n<\/tr>\n<tr>\n<td><strong>Graduate<\/strong><\/td>\n<\/tr>\n<tr>\n<td width=\"15%\">2014 &#8211;<\/td>\n<td width=\"85%\">Yi Zhong, MSc guidance committee member (BME)<\/td>\n<\/tr>\n<tr>\n<td width=\"15%\">2009 &#8211; present<\/td>\n<td>Thesis committee for Shiv Shanmugan, Vinay Sethia, Pavan Sethia, Balambal Subramanian, Hong Wang, and JT Tan: MS in Entrepreneurial Biotechnology Program.<\/td>\n<\/tr>\n<tr>\n<td width=\"15%\">2008 &#8211; 2009<\/td>\n<td>Ashley McKee, undergraduate senior project co-advisor<\/td>\n<\/tr>\n<tr>\n<td width=\"15%\">2008<\/td>\n<td>Michael Pelyak, ENGAGE fellowship sponsor<\/td>\n<\/tr>\n<tr>\n<td width=\"15%\">2006 &#8211; 2012<\/td>\n<td>EBME 325, Introduction to Tissue Engineering, guest lecturer. Department of Biomedical Engineering, CWRU<\/td>\n<\/tr>\n<tr>\n<td width=\"15%\">2005 &#8211; 2006<\/td>\n<td>Ross Anderson, undergraduate senior project co-advisor<\/td>\n<\/tr>\n<tr>\n<td width=\"15%\">1991 &#8211; 1994<\/td>\n<td>Introduction to Microcomputers. Department of Physiology &amp; Biophysics, CWRU<\/td>\n<\/tr>\n<tr>\n<td><strong>Fellows<\/strong><\/td>\n<\/tr>\n<tr>\n<td width=\"15%\">2016 \u2013<\/td>\n<td>Mostafa Motavalli, Ph.D., Postdoctoral Fellow<\/td>\n<\/tr>\n<tr>\n<td width=\"15%\">2014 \u2013<\/td>\n<td>Johnathan Kenyon, Ph.D., Postdoctoral Fellow<\/td>\n<\/tr>\n<tr>\n<td width=\"15%\">2003 &#8211; 2004<\/td>\n<td>Mukund Deglurkar, M.B.B.S., M.S., F.R.C.S. Research Fellow, MD candidate, University of Wales<\/td>\n<\/tr>\n<tr>\n<td width=\"15%\">2003 &#8211; 2004<\/td>\n<td>Reid Wenger, D.D.S., Research Fellow<\/td>\n<\/tr>\n<tr>\n<td width=\"15%\">2002<\/td>\n<td>Rabia Ahmed, summer undergraduate student.<\/td>\n<\/tr>\n<tr>\n<td width=\"15%\">1997 &#8211; 1998<\/td>\n<td>Shmuel Tsurel, M.D.; Research Fellow<\/td>\n<\/tr>\n<tr>\n<td><strong>Other<\/strong><\/td>\n<\/tr>\n<tr>\n<td width=\"15%\">2005 &#8211; 2008<\/td>\n<td>Bioreactors for MSC differentiation; \u201cCell-Based Therapies and Tissue Engineering\u201d (CTTE) short course<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<h3>Funded Research:<\/h3>\n<ul>\n<li>Administrative Supplement to NIH\/NIBIB P41 EB 021911, CWRU center for multi-modal evaluation of engineered cartilage (Caplan, PI), 09\/01\/2018 &#8211; 03\/31\/2019. Project Co-director<\/li>\n<li>NIH\/NIBIB P41 EB 021911, CWRU center for multi-modal evaluation of engineered cartilage (Caplan, PI), 06\/01\/2016 &#8211; 03\/31\/2021. Project Co-director<\/li>\n<li>NIH\/NIAMS R21 proposal, Cartilage repair by condensed mesenchymal stem cell delivery via collagen fabric. 2017 \u2013 2019. Co-Investigator<\/li>\n<li>AFIRM II Project CF-03. 12\/01\/2013-11\/30\/2018. Subproject co-investigator<\/li>\n<li>NIH\/NIBIB R01 EB 20367, CWRU center for multi-modal evaluation of engineered cartilage (Caplan, PI), 08\/01\/2014 &#8211; 07\/31\/2016. Project Co-director<\/li>\n<li>IRT\/Procaps: Pre-clinical Cytogel-MSC 2015 \u2013 2016 Co-PI<\/li>\n<li>AFIRM II 2014 &#8211; 2017 subproject co-investigator.<\/li>\n<li>Intra-articular delivery of injectable sustained-release microsphere drug formulations. CSCRM\/BRCP: 7\/1\/09 \u2013 6\/30\/2012. Principal Investigator<\/li>\n<li>Tissue engineered cartilage repair. (PI: Arnold Caplan) NIH\/NIAMS-NIBIB P01 AR053622 7\/01\/08 &#8211; 06\/30\/10 Core director and sub-project Co-principal investigator<\/li>\n<li>Mechanisms of chondroprotection by pomegranate fruit extract R01 AT003627-01A1 PI: Tariq Haqq i7\/1\/2007 &#8211; 6\/30\/2012 Co-investigator.<\/li>\n<li>Engineering cartilage: an integrated approach to biological joint repair. NIH R01 AR050802. 4\/5\/2005 &#8211; 3\/31\/2010. Principal investigator.<\/li>\n<li>Chondrogenic preconditioning of cell\/scaffold constructs for the repair of large cartilage defects. Arthritis Foundation Biomedical Research Grant. 07\/01\/2002 &#8211; 06\/30\/2005. Principal investigator.<\/li>\n<li>Clinical tissue engineering center (CTEC), BRTT, PI: George Muschler, 04\/01\/2005 &#8211; 03\/31\/2008 Co-investigator.<\/li>\n<li>Tissue-engineered skin with built-in capillary flow networks. NIH R01 EB006203. PI: Harihara Baskaran, 03\/01\/2006 &#8211; 02\/28\/2010, Co-investigator.<\/li>\n<li>Tissue engineering of cartilage subtypes. NIH R01 DE015322. PI: James Dennis, 08\/01\/2004 &#8211; 7\/31\/2008, Co-investigator.<\/li>\n<li>Strength and resorption of biodegradable skull implants. NIH R01-DE13740. PI: David Dean, Co-investigator. Start date pending. Co-investigator.<\/li>\n<li>Effects of processing techniques for tantalum trabecular bone implant surfaces. Zimmer, Inc. PI: Victor Goldberg, 07\/01\/2003 &#8211; 06\/30\/2005, Co-investigator.<\/li>\n<li>State-of-the-Art pH Monitoring in Bioreactors. NSF STTR Phase I. PI: John Robecheck, 07\/01\/03 &#8211; 06\/30\/04, Co-investigator.<\/li>\n<li>Tissue engineered implants for cartilage regeneration. Ohio Board of Regents\/Case Western Reserve University Presidential Research Initiative. 01\/01\/2001 &#8211; 12\/31\/2002. Principal investigator<\/li>\n<li>Gene transcription in mechanically loaded bone cells. NIH R03 AR 45777. 10\/1\/1998 &#8211; 9\/30\/2001. Principal investigator<\/li>\n<\/ul>\n<p><strong>Pending\/Planned Proposals:<\/strong><\/p>\n<ul>\n<li>NIH: Optimization of MSC chondrogenesis for articular cartilage tissue engineering (Caplan, PI). Co-investigator<\/li>\n<li>NIH: Smart tooth platform technology (Yu, PI). Co-investigator<\/li>\n<li>NIH: Cartilage repair by condensed MSC delivery (Akkus, PI). Co-investigator<\/li>\n<li>NIH: Stimulus to compensatory renal growth. (Hostetter, PI). Co-investigator<\/li>\n<\/ul>\n<h3>Ongoing Collaborations:<\/h3>\n<p><strong>At Case Western Reserve University:<\/strong><\/p>\n<ul>\n<li>Russel Wang, D.D.S, M.S.D.: PEEK for maxillofacial reconstruction<\/li>\n<li>Andrew Rollins, Ph.D.: Optical coherence tomography of cartilage<\/li>\n<li>Thomas Hostetter, M.D.: Compensatory renal growth.<\/li>\n<li>Xiong (Bill) Yu, Ph.D.: Smart tooth platform.<\/li>\n<li>David Prologo, M.D.: Intervertebral disc MSC injections.<\/li>\n<li>Ozan Akkus, Ph.D.: Osteochondral tissue engineering.<\/li>\n<li>Joseph Mansour, Ph.D.: Mechanical and ultrasound evaluation of hydrogels and engineered tissue.<\/li>\n<li>Arnold Caplan, Ph.D.: Mesenchymal stem-cell based cartilage tissue engineering.<\/li>\n<li>Davood Varghai: Cranial explant organ culture<\/li>\n<li>David Prologo: Intradisc MSC injections<\/li>\n<li>Harihara Baskaran: Mass transport studies in tissue-engineered cartilage and skin. Metabolic engineering of anaerobic bacteria.<\/li>\n<li>Charles Malemud: Apoptosis in OA.<\/li>\n<li>Victor Goldberg: Porous ingrowth bone implants, bone grafts and bone graft substitutes.<\/li>\n<li>David Dean: Tissue engineering of cranial implants.<\/li>\n<li>Tariq Haqqi: Oxidative stress and MSC performance.<\/li>\n<li>C.C. Liu: Glucose consumption by differentiating mesenchymal stem cells<\/li>\n<\/ul>\n<p><strong>Off Campus:<\/strong><\/p>\n<ul>\n<li>Riccardo Gottardi (Pittsburgh) Mechanically active bioreactors<\/li>\n<li>Pete Alexander (Pittsburgh) Osteochondral tissue engineering<\/li>\n<li>Lisa Freed (MIT) and<\/li>\n<li>Farshid Guilak (Washington U.): Osteochondral tissue engineering<\/li>\n<li>H\u00fclya B\u00fck\u00fclmez, M.D.(MetroHealth): Role of CNP in MSC differentiation.<\/li>\n<li>Olcay Jones (Walter Reed): MSCs in Lupus and Rheumatoid Arthritis<\/li>\n<li>David Dean (Ohio State): Tissue engineering of cranial implants<\/li>\n<li>Tracey Richey\/Mark Smith (Oakwood Labs): Sustained-release intra-articular drug delivery<\/li>\n<li>H. Michael Cheung (University of Akron): Dynamic light scattering in molecular crowding.<\/li>\n<li>Lisa Freed (Massachusetts Institute of Technology): Cartilage tissue engineering.<\/li>\n<li>John Robecheck, (Sensirox, Inc), Jay Johnson (UDRI): Development of micro-pH sensors.<\/li>\n<li>R. Tracy Ballock, (Cleveland Clinic Foundation): Investigation of Heuter-Volkmann effect in vitro using a hydrostatic bioreactor.<\/li>\n<li>Dwayne Bisgrove, Ph.D., System Biosciences (SBI): Lentiviral reporter\/selection vectors to report cell differentiation.<\/li>\n<\/ul>\n<h3>Service to Professional Community:<\/h3>\n<ul>\n<li>2017 \u2013 present Reviewer, Science Foundation Ireland<\/li>\n<li>2013 \u2013 present Reviewer, NMRC (Singapore) Clinician Scientist Awards<\/li>\n<li>2012 \u2013 present International Expert Panel member. National Medical Research Council (Singapore)<\/li>\n<li>2013 <em>Ad hoc<\/em>\u00a0member, NIH Cell Culture Bioreactor Study Section ZRG1 IDM-M (30)<\/li>\n<li>2013 Reviewer NMRC (Singapore) Clinician Scientist Awards<\/li>\n<li>2012 &#8211; 2014 International Expert Panel member. National Medical Research Council (Singapore)<\/li>\n<li>2012 Member, NIH COBRE renewal review panel<\/li>\n<li>2011 Study section member for Arthritis Research UK<\/li>\n<li>2010, 2011 Reviewer, NCRM pilot grant proposals<\/li>\n<li>2009 Moderator, Progenitors and Stem Cells session, Orthopaedic Research Society meeting, Las Vegas, NV<\/li>\n<li>2009 Member, NIH Challenge Grant Review Panel #10, ZRG1 BDA-A (58) R<\/li>\n<li>2008, 2011 Member, Arthritis Research Campaign (U.K.) study section<\/li>\n<li>2008 Member, Special Emphasis Panel\/Scientific Review Group 2009\/01 MTE<\/li>\n<li>2008 <em>Ad hoc<\/em>\u00a0member, NIH Special Emphasis Panel\/Scientific Review Group ZAR1 EHB-H (M1) 1<\/li>\n<li>2006, 2007 <em>Ad hoc<\/em>\u00a0member, NIH Special Emphasis Panel\/Scientific Review Group ZAR1 EHB-J (M1) (1)<\/li>\n<li>2005 <em>Ad hoc<\/em>\u00a0member, NIH Special Emphasis Panel\/Scientific Review Group ZAR1 EHB-G (O1) (1)<\/li>\n<li>2005 Judge, MTEC-2005 presentation awards<\/li>\n<li>2004, 2006-2012 <em>Ad hoc<\/em>\u00a0reviewer for the National Medical Research Council (Singapore) study section<\/li>\n<li>2004, 2006, 2007 Judge, graduate student poster competition at Research ShowCASE<\/li>\n<li>2003 Organizing committee for the 5th Bone Fluid Flow Workshop, Cleveland, OH. September 17 &#8211; 18<\/li>\n<li>2002 &#8211; 2003 <em>Ad hoc<\/em>\u00a0member, NIH biomedical engineering study section ZRG1 SSS-M 58<\/li>\n<li>2001 &#8211; 2004 Member, Department of Orthop\u00e6dics Research Committee<\/li>\n<li>*\u00a0<em>Ad hoc<\/em>\u00a0reviewer for Acta Biomaterialia<\/li>\n<li>*\u00a0<em>Ad hoc<\/em>\u00a0reviewer for Arthritis Research and Therapy<\/li>\n<li>*\u00a0<em>Ad hoc<\/em>\u00a0reviewer for Biomaterials<\/li>\n<li>*\u00a0<em>Ad hoc<\/em>\u00a0reviewer for BioTechniques<\/li>\n<li>*\u00a0<em>Ad hoc<\/em>\u00a0reviewer for Bone<\/li>\n<li>*\u00a0<em>Ad hoc<\/em>\u00a0reviewer for British Journal of Cancer<\/li>\n<li>*\u00a0<em>Ad hoc<\/em>\u00a0reviewer for Cells, Tissues, Organs<\/li>\n<li>*\u00a0<em>Ad hoc<\/em>\u00a0reviewer for Current Eye Research<\/li>\n<li>*\u00a0<em>Ad hoc<\/em>\u00a0reviewer for Genomics<\/li>\n<li>*\u00a0<em>Ad hoc<\/em>\u00a0reviewer for the Journal of Biological Chemistry<\/li>\n<li>*\u00a0<em>Ad hoc<\/em>\u00a0reviewer for the Journal of Biomedical Materials Research<\/li>\n<li>*\u00a0<em>Ad hoc<\/em>\u00a0reviewer for the Journal of Investigative Dermatology<\/li>\n<li>*\u00a0<em>Ad hoc<\/em>\u00a0reviewer for the Journal of Orthop\u00e6dic Research<\/li>\n<li>*\u00a0<em>Ad hoc<\/em>\u00a0reviewer for the Orthop\u00e6dic Research Society<\/li>\n<li>*\u00a0<em>Ad hoc<\/em>\u00a0reviewer for Tissue Engineering<\/li>\n<li>*\u00a0<em>Ad hoc<\/em>\u00a0reviewer for Yonsei Medical Journal<\/li>\n<\/ul>\n<h3>Patents:<\/h3>\n<ul>\n<li>Mansour, J.M.; Motavalli, M.; and Welter, J.F.: Method to rapidly detect shear-induced damage in tissue engineering cartilage, Provisional patent application number 62\/539,793 filed August 2017.<\/li>\n<li>Holt, V.; Welter, J.F.; Berilla, J.A.; Harris, M.; and Caplan, A.I.: Cell capture apparatus and staining device. Provisional patent application number 61\/875918 filed September 10, 2013.<\/li>\n<li>Welter, J.F.; Solchaga, L.A.; Berilla, J.A.; and Penick, K.: Apparatus and method for tissue engineering. US Patent # 8,507,266 issued August 13, 2013.<\/li>\n<\/ul>\n<h3>Publications:<\/h3>\n<p><strong>Manuscripts Submitted\/in Preparation:<\/strong><\/p>\n<ol>\n<li>Motavalli, M.; Berilla, J.; Schluchter, M.; Welter, J.F; and Mansour, J.: Rapid evaluation of articular cartilage anisotropy using ultrasound. (submitted)<\/li>\n<li>Prologo, J.D.; Duesler, L.; Berilla,J.A.; Baskaran, H.; Schluchter, M.D.; and Welter, J.F.: Impact of concurrent pressure and shear on MSC viability and differentiation during simulated intervertebral disk needle injection. Journal of Vascular and Interventional Radiology 2014, (<em><a href=\"http:\/\/www.case.edu\/artsci\/biol\/skeletal\/pdfs\/prologo.pdf\">Submitted<\/a><\/em>)<\/li>\n<li>Solchaga, L.A.; Penick, J.; Goldberg, V.M.; Caplan, A.I; and Welter, J.F.: TGF-\u03b21 and dexamethasone regulate hypertrophy during chondrogenic differentation of bone marrow-derived mesenchymal stem cells (<em>in preparation<\/em>)<\/li>\n<li>Berilla, J.; Solchaga, L.A.; Baskaran, H.; and Welter, J.F.: Design of a cartilage tissue engineering bioreactor (<em>submitted<\/em>)<\/li>\n<li>Liang, W.H.; Janakiraman, V.; Welter, J.F.; and Baskaran, H.: Composite tissue engineered skin constructs made of collagen dermal analogs and cultured keratinocyte epidermal analogs (in preparation)<\/li>\n<li>Berilla, J. and Welter, J.F.: Image analysis algorithm for measuring local thickness (<em>in revision<\/em>)<\/li>\n<li>Welter, J.F.; Baskaran, H.; Berilla, J.A.; Caplan, A.I; Goldberg, V.M.; Penick, K.; and Solchaga, L.A.: Transient aggregate culture enables human mesenchymal stem cell-based cartilage tissue engineering (<em>in preparation<\/em>)<\/li>\n<li>Welter, J.F.: Simplified color thresholding of histological images using color-space rotation. (<em>in preparation<\/em>)<\/li>\n<li>Welter, J.F. and Mansour, J.M.: Evaluation of tissue engineered cartilage (<em>in preparation<\/em>)<\/li>\n<\/ol>\n<p><strong>Peer-Reviewed Manuscripts:<\/strong><\/p>\n<ol>\n<li>Dai, Y.; Somoza, R.A.; Wang, L.; Welter, J.F.; Li, Y.; Caplan, A.I.; Liu, C.C.: Exploring the trans-cleavage activity of CRISPR Cas12a for the development of a universal electrochemical biosensor. Angewandte Chemie, 2019 doi: 10.1002\/ange.201910772, PMID: 31568601 <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31568601\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Larson, B.L.; Yu, S.N.; Park, H.; Estes, B.T.; Moutos, F.T.; Bloomquist, C.J.; Wu, P.B.; Welter, J.F.; Langer, R.; Guilak, F.; and Freed, L.E.: Cartilaginous and osteochondral tissue formation by human mesenchymal stem cells on three-dimensionally woven scaffolds. Journal of Tissue Engineering and Regenerative Medicine, 2019 PMID: 31115161, DOI: 10.1002\/term.2899 <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31115161\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Mansour, J.M.; Motavalli, M.; Dennis, J.E.; Kean, T.J.; Caplan, A.I.; Berilla, J.A.; and Welter, J.F.: Rapid detection of shear-induced damage in tissue engineered cartilage using ultrasound. Tissue engineering, part C, 2018, 24(8):443-456. PMID: 29999475, PMCID: PMC6088252. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/29999475\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Zhong, Y.; Motavalli, M.; Caplan, A.I.; Welter, J.F.; and Baskaran, H.: Dynamics of intrinsic glucose uptake kinetics in human mesenchymal stem cells during chondrogenesis. Annals of Biomedical Engineering, 2018, 46:1896-1910. PMID: 29948374, PMCID: PMC6204100. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/29948374\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Wang, K-C.; Egelhoff, T.T.; Caplan, A.I.; Welter, J.F.; Baskaran, H.: ROCK Inhibition promotes development of chondrogenic tissue by improved mass transport, Tissue Engineering Part A, 2018, 24:1218-1227. PMID: 29397789, PMCID: PMC6080111. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/29397789\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Chou, C.-L.; Rivera, A.L.; Williams, V.; Welter, J.F.; Mansour, J.M.; Drazba, J.A.; Sakai, T.; and Baskaran, H.: Micrometer scale guidance of mesenchymal stem cells to form structurally oriented large-scale tissue engineered cartilage Acta Biomaterialia 2017, 60:210-219. PMID: 28709984, PMCID: PMC5581212. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28709984\">Abstract<\/a><\/li>\n<li>Verbus, E.A.; Kenyon, J.D.; Sergeeva, O.; Awadallah, A.; Yuan, L.; Welter, J.F.; Caplan, A.I.; Schluchter, M.D.; Khalil, A.M.; and Lee, Z.: Expression of miR-145-5p during chondrogenesis of mesenchymal stem cells Journal of Stem Cell Research (Overl Park) 2017, 1(3):1-10. PMID: 29721552, PMCID: PMC5926818. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/29721552\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<\/li>\n<li>Mishra, R.; Sefcik, R.S.; Bishop, T.J.; Montelone, S.M.; Crouser, N.; Welter, J.F.; Caplan, A.I.; and Dean, D.: Growth factor dose tuning for bone progenitor cell proliferation and differentiation on resorbable poly(propylene fumarate) scaffolds. Tissue Engineering Part C Methods. 2016 22(9):904-913. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27558310\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Mansour, J.; Lee, Z.; and Welter, J.: Nondestructive techniques to evaluate the characteristics and development of engineered cartilage. (Invited review). Annals of Biomedical Engineering 2016 44(3):733-49. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26817458\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Chung, C.Y.; Heebner, J.; Baskaran, H.; Welter, J.F.; and Mansour, J.M.: Ultrasound elastography for estimation of regional strain of multilayered hydrogels and tissue-engineered cartilage. Ann Biomed Eng. 2015 43(12):2991-2300 <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26077987\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract\u00a0<\/a><\/li>\n<li>Mansour, J.M.; Gu, D.-W.; Chung, C.-Y.; Heebner, J.; Schluchter, M.D.; and Welter, J.F.: Towards the feasibility of using ultrasound to determine mechanical properties of tissues in a bioreactor. Annals of Biomedical Engineering 2014 42(10):2190-202 <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25092421\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Correa, D.; Somoza, R.A.; Lin, P.; Greenberg, S.; Rom, E.; Duesler, L.; Welter, J.F.; Yayon, A.; and Caplan, A.I.: Sequential exposure to fibroblast growth factors (FGF) 2, 9 and 18 enhances hMSC chondrogenic differentiation. Osteoarthritis Cartilage. 2015 23(3):443-53. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25464167\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Somoza, R.; Welter, J.; Correa, D.; and Caplan, A.: Chondrogenic differentiation of Mesenchymal Stem Cells: unfulfilled expectations and new challenges. Tissue Engineering part B 2014, 20(6):596-608\u00a0PMID: 24749845, PMCID: PMC4241862<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24749845\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Wallace, J.; Wang, M.O.; Thompson, P.; Busso, M.; Belle, V.; Mammoser, N.; Kim, K.; Fisher, J.P.; Siblani, A.; Xua, Y.; Welter, J.F.; Lennon, D.P.; Sun, J.; Mikos, A.G.; Caplan, A.I.; Dean, D.: Validating continuous digital light processing (cDLP) additive manufacturing accuracy and tissue engineering utility of a dye-initiator package. Biofabrication 2014 6(1)\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24429508\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Welter, J.F.; Penick, J.; Solchaga, L.A.: Assessing adipogenic potential of mesenchymal stem cells: a rapid three-dimensional culture screening technique. Stem Cells International, 2013, Article ID 806525\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23431315\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Chou, C.-L.; Rivera, A.L.; Caplan, A.I.; Goldberg, V.M.; Welter, J.F.; and Baskaran, H.: Micrometer scale guidance of mesenchymal stem cells to form structurally oriented cartilage extracellular matrix. Tissue Engineering, Part A 2013, 19(9-10):1081 &#8211; 1090.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23157410\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Mansour, J.M. and Welter, J.F.: Multimodal evaluation of tissue-engineered cartilage. Journal of Medical and Biological Engineering 2013, 33(1):1-16\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23606823\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Shao, Y.; Wang, L.; Welter, J.F.; and Ballock, R.T.: Primary cilia modulate ihh signal transduction in response to hydrostatic loading of growth plate chondrocytes. Bone 2012, 50(1):79 &#8211; 84\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21930256\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Walker, J.M.; Myers, A.M.; Schluchter, M.D.; Goldberg, V.M.; Caplan, A.I.; Berilla, J.A.; Mansour, J.M.; and Welter, J.F.: Nondestructive Evaluation of Hydrogel Mechanical Properties Using Ultrasound. Annals of Biomedical Engineering 2011, 39(10):2521 &#8211; 2530<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21773854\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Sarkar, S.; Bustard, B.L.; Welter, J.F.; and Baskaran, H.: Combined experimental and mathematical approach for development of microfabrication-based cancer migration assay. Annals of Biomedical Engineering 2011, 39(9):2346 &#8211; 2359.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21701934\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Auletta, J.J.; Zale, E.A.; Welter, J.; and Solchaga, L.: Fibroblast growth factor-2 enhances expansion of human bone marrow-derived mesenchymal stromal cells without diminishing their immunosuppressive potential. Stem Cells International 2011, Article ID 235176:1 &#8211; 10.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21437189\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Abrahamsson, C.A.; Yang, F.; Park, H.; Valonen, P.K.; Langer, R.; Welter, J.F.; Caplan, A.I.; Brunger, J.; Guilak, F.; Freed, L.E.: Chondrogenesis and mineralization during in vitro culture of human mesenchymal stem cells on 3D-woven scaffolds. Tissue Engineering, Part A 2010, 16(12):3709 &#8211; 3718).\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20673022\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Liang, W.H.; Kienitz, B.L.; Penick, K.; Welter, J.F.; and Baskaran, H.: Optimizing collagen-GAG scaffolds for tissue engineering applications using centrifugation. Journal of Biomedical Materials Research, Part A 2010, 94(4):1050 &#8211; 1060.<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20694972\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Valonen, P.K.; Moutos, F.T.; Kusanagi, A.; Moretti, M.; Diekman, B.O.; Welter, J.F.; Caplan, A.I.; Guilak, F.; and Freed, L.E: In vitro generation of mechanically functional cartilage grafts based on adult human stem cells and 3D-woven poly(\u03b5-caprolactone) scaffolds. Biomaterials 2010, 31(8):2193 \u2013 2200.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20034665\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Solchaga, L.A.; Penick, J.; Goldberg, V.M.; Caplan, A.I.; and Welter, J.F.: Fibroblast growth factor-2 enhances proliferation and delays loss of chondrogenic potential in human adult bone marrow-derived mesenchymal stem cells. Tissue Engineering 2009, (<em>e-Pub ahead of print<\/em>).\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19842915\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Welter, J.F.; Solchaga, L.A.; and Penick, K.J.: Simplification of aggregate culture of human mesenchymal stem cells as a chondrogenic screening assay. BioTechniques 2007, 42(6):732 &#8211; 737.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17612296\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Henderson, J.H.; Welter, J.F.; Mansour, J.M.; Niyibizi, C.; Caplan, A.I; and Dennis, J.E.: Cartilage tissue engineering for pediatric laryngotracheal reconstruction: Comparison of chondrocytes from three anatomic locations in the rabbit. Tissue Engineering 2007, 13(4):843 &#8211; 853.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17394383\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Deglurkar, M.; Davy, D.T.; Goldberg, V.M.; Stewart, M.C.; and Welter, J.F.: Evaluation of machining methods for porous tantalum implants in a rabbit intramedullary osseointegration model. Journal of Biomedical Materials Research (B) 2007, 80B(2):528 &#8211; 540.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16838356\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Henderson, J.H.; Mansour, J.M.; Welter, J.F.; Awadallah, A.; Ginley, N.; Caplan, A.I.; and Dennis, J.E.: Cartilage tissue engineering: comparison of chondrocytes from three anatomic locations in the rabbit. CWRU Orthopaedic Journal 2006, 3(1):33- 42.<\/li>\n<li>Solchaga, L.A.; Tognana, E.; Penick, K.; Baskaran, H.; Caplan, A.I.; Goldberg, V.G.; and Welter, J.F.: A rapid vacuum-seeding technique for the assembly of large tissue-engineered cell\/scaffold composites. Tissue Engineering 2006, 12(7):1851 &#8211; 1863.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16889515\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Wenger, R.; Hans, M.G.; Welter, J.F.; Solchaga, L.A.; Sheu, Y.R.; and Malemud, C.J.: Tissue-engineered human cartilage-constructs from human osteoarthritic chondrocytes. Frontiers in Biosciences, 2006, 11:1690 &#8211; 1695.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16368547\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Penick, K.J.; Solchaga, L.A.; and Welter, J.F.: A high-throughput aggregate culture system to assess the chondrogenic potential of mesenchymal stem cells. BioTechniques 2005, 39(5):687 &#8211; 691.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16312217\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Penick, K.; Berilla, J.; Solchaga, L.A.; and Welter, J.F.: Performance of polyoxymethylene plastic (POM) as a component of a tissue engineering bioreactor. Journal of Biomedical Materials Research 2005, 75(1):168 &#8211; 174.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16052509\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Solchaga, L.A.; Penick, K.; Porter, J.; Caplan, A.I.; Goldberg, V.M.; and Welter, J.F.: FGF-2 enhances the mitotic and chondrogenic potentials of human adult bone marrow-derived mesenchymal stem cells. J. Cellular Physiology 2005, 203:398 &#8211; 409.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15521064\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Solchaga, L.A.; Penick, K.; and Welter, J.F.: A manual mosaicking approach to generating large, high resolution digital images of histological sections. Proceedings of the Royal Microscopical Society 2004, 39(4):313 &#8211; 320.<\/li>\n<li>Stewart, M.C.; Welter, J.F.; and Goldberg, V.G.: Effect of Hydroxyapatite\/Tricalcium-Phosphate coating on osseointegration of plasma-sprayed titanium alloy implants. Journal of Biomedical Materials Research 2004, 69A(1):1 &#8211; 10.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/14999745\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Jabbour, L.; Welter, J.F.; Kollar, J.; and Hering, T.M.: Sequence, gene structure, and expression pattern of CNTL, a minor class intron-containing gene: evidence for a role in apoptosis. Genomics 2003, 81(3):292 &#8211; 303.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/12659813\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Islam, N.; Haqqi, T.M.; Jepsen, K.J.; Kraay, M.; Welter, J.F.; Goldberg, V.M.; and Malemud, C.J.: Hydrostatic pressure induces apoptosis in human chondrocytes from osteoarthritic cartilage through up-regulation of tumor necrosis factor-\u03b1, inducible nitric oxide synthase, c-myc, p53 and bax-\u03b1, and suppression of bcl-2. Journal of Cellular Biochemistry 2002, 87: 266 &#8211; 278.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/12397608\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Balasubramanian, S.; Agarwal, C.; Efimova, T.; Dubyak, G.R.; Banks, E.; Welter, J.; and Eckert, R.L.: Thapsigargin suppresses phorbol ester-dependent human involucrin promoter activity by suppressing CCAAT-enhancer-binding protein alpha (C\/EBP\u03b1) DNA binding. Biochemical Journal 2000, 350(Pt 3):791 &#8211; 796.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/10970794\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Agarwal, C.; Effimova, T.; Welter, J.F.; Crish, J.F.; and Eckert, R.L.: CCAAT\/Enhancer-binding proteins. A role in regulation of human involucrin promoter response to phorbol ester. Journal of Biological Chemistry 1999, 274(10):6190 &#8211; 6194.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/10037704\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Effimova, T.; LaCelle, P.; Welter, J.F.; and Eckert, R.L.: Regulation of human involucrin promoter activity by a protein kinase C, RAS, MEKK1, MEK3, P38\/RK, AP-1 signal transduction pathway. Journal of Biological Chemistry 1998, 273(38):24387 &#8211; 24395.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/9733728\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Banks, E.B.; Crish, J.F.; Welter, J.F.; and Eckert, R.L.: Characterization of human involucrin promoter distal regulatory region transcriptional activator elements &#8211; a role for SP1 and AP-1 binding sites. Biochemical Journal 1998, 331(Pt.1):61 &#8211; 69.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/9512462\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Robinson, N.A.; Lapic, S.; Welter, J.F.; and Eckert, R.L.: S100A11, S100A10, annexin I, desmosomal proteins, SPRs, plasminogen activator inhibitor-2, and involucrin are components of the cornified envelope of cultured human epidermal keratinocytes. Journal of Biological Chemistry 1997, 272(18):12035 &#8211; 12046.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/9115270\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Eckert R.L.; Crish J.F.; Banks E.B.; Welter, J.F.: The epidermis: genes on &#8211; genes off. Journal of Investigative Dermatology 1997, 109(4): 501 &#8211; 509.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/9326381\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Eckert, R.L. and Welter, J.F.: Keratinocyte differentiation: genes and their regulation. Cell Death and Differentiation 1996, 3:373 &#8211; 383.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17180107\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Eckert, R.L. and Welter, J.F.: Transcription factor regulation of epidermal keratinocyte gene expression. Molecular Biology Reports 1996, 23:59 &#8211; 70.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/8983019\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Welter, J.F.; Gali, H.U.; Crish, J.F.; and Eckert, R.L.: Regulation of human involucrin promoter activity by POU domain proteins. Journal of Biological Chemistry 1996, 271(25):14727 &#8211; 14733.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/8663077\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Welter, J.F.; Crish, J.F.; Agarwal, C.; and Eckert, R.L.: Additions and corrections to: Fos related antigen (Fra-1), junB and junD activate human involucrin promoter transcription by binding to proximal and distal AP1 sites to mediate phorbol ester effects on promoter activity. Journal of Biological Chemistry 1996, 271(18):11034. PMID: 8662708<\/li>\n<li>Welter, J.F. and Eckert, R.L.: Differential expression of the fos and jun family members c-fos, fosB, fra-1, fra-2, c-jun, junB and junD during human epidermal differentiation. Oncogene 1995, 11(12):2681 &#8211; 2687.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/8545126\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Welter, J.F.; Crish, J.F.; Agarwal, C.; and Eckert, R.L.: Fos related antigen (fra-1), junB and junD activate human involucrin promoter transcription by binding to proximal and distal AP1 sites to mediate phorbol ester effects on promoter activity. Journal of Biological Chemistry 1995, 270(21):12614 &#8211; 12622.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/7759510\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Eckert, R.L.; Yaffe, M.B.; Crish, J.F.; Murthy, S.; Rorke, E.A.; and Welter, J.F.: Involucrin &#8211; Structure and role in envelope assembly. Journal of Investigative Dermatology 1993, 100(5):613 &#8211; 617.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/8098344\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Welter, J.F.; Shaffer, J.W.; Stevenson, S.; Davy, D.T.; Field, G.A.; Klein L.; Li, X.Q.; Zika, J.M.; and Goldberg, V.M.: Cyclosporin A and tissue antigen matching in bone transplantation. Fibular allografts studied in the dog. Acta Orthop\u00e6dica Scandinavica 1990, 61(6):517 &#8211; 527.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/2281759\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<\/ol>\n<p><strong>Book Chapters:<\/strong><\/p>\n<ol>\n<li>Welter, J.F. and Baskaran, H.: Chapter 86 &#8211; Monitoring and Real-Time Control of Tissue Engineering Systems. In: Principles of tissue engineering, 5th edition, Lanza, R. ed. 2019 (invited Chapter, <em>in press<\/em>)<\/li>\n<li>Lee, Z.; Dennis, J.; Welter, J.; and Caplan, A.: Imaging stem cell differentiation for cell-based tissue repair. In: Methods in Enzymology: Imaging and Spectroscopy in Living Cells, Elsevier Publishing 2012 506:247-63. PMID: 22341228<\/li>\n<li>Welter, J.F.; Solchaga, L.A.; and Baskaran, H.: Chondrogenesis from human mesenchymal stem cells: Role of culture conditions. In: Hayat, E., ed.: Stem cells and cancer stem cells: Therapeutic applications in disease and injury, volume 5. Springer 2012:269 &#8211; 281 ISBN: 978-94-007-2899-8<\/li>\n<li>Solchaga, L.A.; Penick, K.J.; and Welter, J.F.: Chondrogenic differentiation of bone marrow-derived mesenchymal stem cells: tips &amp; tricks. In: Vemuri, M.C.; Rao, M.S.; and Chase, L.G., eds.: Mesenchymal Stem Cell Assays and Applications. Humana Press, 2011, 698:253 &#8211; 278.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21431525\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Goldberg, V.M. and Welter, J.F.: Autografts. In: Callaghan, J.J.; Rosenberg, A.G.; and Rubash, H.E., eds.: The adult hip, Lippincott-Raven. 2006(23):304 &#8211; 328.<\/li>\n<li>Welter, J.F. and Goldberg, V.M.: Bone grafting and substitutes. In: Orthop\u00e6dic knowledge update. AAOS, 2005:241 &#8211; 248.<\/li>\n<li>Solchaga, L.A.; Welter, J.F.; and Caplan, A.I.: Generation of pluripotent stem cells and their differentiation to the chondrocytic phenotype. In: Sabatini, M.; De Ceuninck, F.; and Pastoureau, P., eds.: Cartilage and osteoarthritis (Methods in Molecular Medicine series). Humana Press, 2004:53 &#8211; 68.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15280587\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Welter, J.F.; Solchaga, L.A.; and Stewart, M.C.: High efficiency non-viral transfection of chondrocytes. In: Sabatini, M.; De Ceuninck, F.; and Pastoureau, P., eds.: Cartilage and osteoarthritis (Methods in Molecular Medicine series). Humana Press, 2004:129 &#8211; 146.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15280593\" target=\"_blank\" rel=\"noopener noreferrer\">Abstract<\/a><\/li>\n<li>Solchaga, L.A.; Welter, J.F.; Caplan, A.I; and Goldberg, V.M.: Cartilage Tissue Engineering. In: Callaghan, J.J.; Rosenberg, A.G.; Rubash, H.E.; Simonian, P.T.; and Wickiewicz, T.L., eds.: The adult knee. Lippincott, Williams &amp; Wilkins, Publishers, 2003:251 &#8211; 258.<\/li>\n<\/ol>\n<p><strong>Abstracts:<\/strong><\/p>\n<ol>\n<li>Motavalli, M.; Blackburn, B.; Welter, J.; Mansour, J.; Rollins, A.: Optical coherence tomography analysis of articular cartilage under dynamic biaxial loads. TERMIS 2019, Orlando, FL, December 2-5, Poster 172 (accepted).<\/li>\n<li>Motavalli, M.; Jones, C.; Welter, J.F.; Berilla, J.; Li, M.; Schluchter, M.; Mansour, J.: Freeze-thaw cycling effects on articular cartilage anisotropy using ultrasound techniques TERMIS 2019, Orlando, FL, December 2-5, Presentation 118. (accepted).<\/li>\n<li>Zhang, B.; Zhong, Y.; Berilla, J.; Motavalli, M.; Welter, J.F.; Caplan, A.I.; Clark, K.L.; Pirosa, A.; Alexander, P.; and Baskaran, H.: Bioreactor development for joint segmentation model to investigate toxicants\/teratogens. BMES 2019 Philadelphia, PA (accepted).<\/li>\n<li>Motavalli, M.; Blackburn, B.; Welter, J.F.; Mansour, J.M.; and Rollins, A.M.: Articular cartilage mechanical behavior under dynamic biaxial loads: optical coherence tomography analysis. BMES 2019 Philadelphia, PA (accepted).<\/li>\n<li>Motavalli, M.; Jones, C.; Welter, J.F.; Berilla, J.; Li, M.; Schluchter, M.; and Mansour, J.: Acoustic anisotropy of articular cartilage and effects of freeze-thaw cycling. BMES 2019 Philadelphia, PA (accepted).<\/li>\n<li>Zhong, Y.; Welsh, A.; Caplan, A.I.; Welter, J.F.; and Baskaran, H.: Essential amino acids metabolism during human mesenchymal stem cell chondrogenesis. BMES 2019 Philadelphia, PA (accepted).<\/li>\n<li>Jones, C.; Motavalli, M.; Berilla, J.; Mansour, J.; and Welter, J.F.: Evaluation of articular cartilage using ultrasound and anisotropic techniques. SEO 2019 poster session, Cleveland, OH, July 25, 2019. Poster # 24<\/li>\n<li>Welter, J.F.; Baskaran, H.; Mansour, J.M.; Somoza, R.A.; Lee, Z.; Khalil, A.; Li, M.; Huang, A.; Kenyon, J.; Motavalli, M.; and Caplan, A.I.: CWRU Center for Multimodal Evaluation of Engineered Cartilage. Proceedings of the 2019 Research ShowCASE, Poster 030. Case Western Reserve University, Cleveland, OH, April 19, 2019.<\/li>\n<li>Zhong, Y., Welter, J.F.; Caplan, A.I.; and Baskaran, H.: Biomolecular rate indicators of human mesenchymal stem cell chondrogenesis. Proceedings of the 2019 Research ShowCASE, Poster 286. Case Western Reserve University, Cleveland, OH, April 19, 2019.<\/li>\n<li>Motavalli, M.; Blackburn, B.; Welter, J.; Mansour, J.M.; Rollins, A.: Articular cartilage mechanical behavior under dynamic biaxial loads: Optical coherence tomography analysis. Proceedings of the 2019 Research ShowCASE, Poster 297. Case Western Reserve University, Cleveland, OH, April 19, 2019. (Mostafa Motavalli won first prize for post-doctoral poster presentations)<\/li>\n<li>Jones, C.; Motavalli, M.; Berilla, J.; Mansour, J.; and Welter, J.: Evaluation of freezing effects on articular cartilage using ultrasound techniques. Proceedings of the 2019 Research ShowCASE, Poster 454. Case Western Reserve University, Cleveland, OH. April 19, 2019.<\/li>\n<li>Blackburn, B.; Motavalli, M.; Ford, M.; Welter, J.; Mansour, J.; and Rollins, A.: Ex vivo measurement of biaxial strain distribution in articular cartilage with optical coherence tomography. 2019 SPIE Photonics West, San Francisco, CA, February 5-7.<\/li>\n<li>Zhong, Y.; Sivakumar, S.; Caplan, A.I.; Welter, J.F.; and Baskaran, H.: Secretome indicators of end tissue quality during human mesenchymal stem cell chondrogenesis. AIChE 2018 Pittsburgh, PA, October 28 \u2013 November 2, Paper 176h.<\/li>\n<li>Zhong, Y.; Sivakumar, S.; Caplan, A.I.; Welter, J.F.; and Baskaran, H.: Biomolecular rate indicators of human mesenchymal stem cell chondrogenesis. AIChE 2018 Pittsburgh, PA, October 28 \u2013 November 2, Paper 190h<\/li>\n<li>Zhong, Y.; Sivakumar, S.; Caplan, A.I.; Welter, J.F.; and Baskaran, H.: Biomolecular rate indicators for human mesenchymal stem cell chondrogenesis. BMES 2018, Atlanta, GA, October 17-20, Presentation Sa-3-15<\/li>\n<li>Motavalli, M.; Berilla, J.; Schluchter, M.; Welter, J.; and Mansour, J.: Evaluation of articular cartilage anisotropy using ultrasound technique. BMES 2018, Atlanta, GA, October 17-20, Poster FRI-181<\/li>\n<li>Blackburn, B.; Motavalli, M.; Rollins, A.; Welter, J.; and Mansour, J.: Optical coherence elastography for analysis of articular cartilage deformation under biaxial loads. BMES 2018, Atlanta, GA, October 17-20 Presentation Th-1-7<\/li>\n<li>Baskaran, H.; Motavalli, M.; and Welter, J.F.: CWRU Center for Multimodal Evaluation of Engineered Cartilage. Exhibitor booth # 200. BMES 2018, Atlanta, GA, October 17-20.<\/li>\n<li>Welter, J.F.; Baskaran, H.; Mansour, J.M.; Somoza, R.A.; Lee, Z.; Khalil, A.; Schluchter, M.D.; Huang, A.; Kenyon, J.; Motavalli, M.; and Caplan, A.I: CWRU Center for Multimodal Evaluation of Engineered Cartilage. A Biomedical Technology Resource Center funded by the National Institute of Biomedical Imaging and Bioengineering. Proceedings of the 2018 Research ShowCASE, Case Western Reserve University, Cleveland, OH. April 20, 2018.<\/li>\n<li>Motavalli, M.; Myers, J.; Huang, A.; Welter, J.; and Mansour, J.: 3D displacement fields in cartilage under compression using two-photon microscopy. Proceedings of the 2018 Research ShowCASE, Case Western Reserve University, Cleveland, OH. April 20, 2018.<\/li>\n<li>Zhong, Y.; Berilla, J.; Motavalli, M.; Welter, J.F.; Caplan, A.I.; Tuan, R.S.; Alexander, P.; and Baskaran, H.: Bioreactor for joint segmentation model to investigate toxicants\/teratogens. Proceedings of the 2018 Research ShowCASE, Case Western Reserve University, Cleveland, OH. April 20, 2018.<\/li>\n<li>Motavalli, M.; Myers, J.; Huang, A.; Welter, J.; and Mansour, J.: 3D displacement fields in cartilage under compression using two-photon microscopy. Poster 511. TERMIS 2017 Charlotte, NC, December 3-6, 2017.<\/li>\n<li>Motavalli, M.; Berilla, J.; Dennis, J.; Caplan, A.; Mansour, J.; and Welter, J.: Using ultrasound for non-destructive evaluation of engineered cartilage damage by sliding shear. Poster 416. TERMIS 2017 Charlotte, NC, December 3-6, 2017.<\/li>\n<li>Zhong, Y.; Berilla, J.; Motavalli, M.; Welter, J.F.; Caplan, A.I.; Tuan, R.S.; Alexander, P.; and Baskaran, H.: Bioreactor for joint segmentation model to investigate toxicants\/teratogens. Poster 594. TERMIS 2017 Charlotte, NC, December 3-6, 2017.<\/li>\n<li>Motavalli, M.; Zhong, Y.; Caplan, A.I; Welter, J.; and Baskaran, H.: Dynamics of intrinsic kinetics of glucose uptake during chondrogenesis. Presentation OP-TH-2-7. BMES 2017, Phoenix, AZ, October 11-14.<\/li>\n<li>Zhong, Y.; Pontius, W.D; Wang, K.-C.; Motavalli, M.; Caplan, A.I.; Welter, J.F.; and Baskaran, H.; Glucose metabolism during mesenchymal stem cell chondrogenesis. BMES 2017, Phoenix, AZ, October 11-14, poster P-TH-550<\/li>\n<li>Motavalli, M.; Berilla, J.; Dennis, J.; Caplan, A.; Mansour, J.; and Welter, J.: Non-destructive evaluation of engineered cartilage damage by sliding shear using ultrasound. Poster P-TH-298. BMES 2017, Phoenix, AZ, October 11-14.<\/li>\n<li>Motavalli, M; Myers, J.; Huang, A.; Welter, J.; and Mansour, J.: Determining 3D displacement fields in cartilage using two-photon microscopy. Presentation OP-SA-1-3. BMES 2017, Phoenix, AZ, October 11-14.<\/li>\n<li>Baskaran, H.; Motavalli, M.; and Welter, J.F.: CWRU Center for multimodal evaluation of engineered cartilage. BMES 2017, Phoenix, AZ, October 11-14, exhibitor booth #301.<\/li>\n<li>Sergeeva, O.; Kenyon, J.; Verbus, E.; Awadallah, A.; Welter, J.; Caplan, A.; Schluchter, M.; Khalil, A.; and Lee, Z.: Imaging chondrogenesis with miR-145-responsive reporter. 2017 World Molecular Imaging Congress, Philadelphia, PA, September 13-16. 2017. (Presented September 15).<\/li>\n<li>Wang, K.-C.; Kwan, E.; Aris, K.; Egelhoff, T.T.; Caplan, A.I.; Welter, J.F.; and Baskaran, H.: The effect of RhoA\/ROCK signaling inhibition on the development of hMSC-based chondrogenic tissue. OARSI 2017 annual meeting, Las Vegas, NV, April 27-30, 2017.<\/li>\n<li>Zhong, Y.; Pontius, W.D.; Wang, K.-C.; Motavalli, S.; Caplan, A.I.; Welter, J.F.; and Baskaran, H.: Glucose metabolism during mesenchymal stem cell chondrogenesis. OARSI 2017 annual meeting, Las Vegas, NV, April 27-30, 2017.<\/li>\n<li>Welter, J.F.; Baskaran, H.; Mansour, J.M.; Somoza, R.; Lee, Z.; Khalil, A.; Schluchter, M.D.; Huang, A.; Kenyon, J.; Motavalli, M.; and Caplan, A.I.: CWRU Center for Multimodal Evaluation of Engineered Cartilage. A Biomedical Technology Resource Center Funded by the National Institute of Biomedical Imaging and Bioengineering. Proceedings of the 2017 Research ShowCASE, Case Western Reserve University, Cleveland, OH. April 21, 2017.<\/li>\n<li>Wang, K.-C.; Zhong, Y.; Thomas, D.; Egelhoff, T.; Caplan, A.I.; Welter, J.; and Baskaran, H.: Chondrogenic enhancement in human mesenchymal stem cells via RhoA\/ROCK signaling inhibition. BMES annual meeting, Minneapolis, MN October 5-8, 2016.<\/li>\n<li>Zhong, Y.; Pontius, W.D.; Caplan, A.I.; Welter, J.F.; and Baskaran, H.: Use glucose metabolism as a predictive tool to study chondrogenesis in human mesenchymal stem cells. OARSI 2016 annual meeting Amsterdam, The Netherlands, March 31-April 3, 2016 (Poster #281).<\/li>\n<li>Pontius, W.; Zhong, Y.; Caplan, A.I.; Welter, J.F.; and Baskaran, H.: Using glucose metabolism as a predictive tool to study chondrogenesis in human mesenchymal stem cells. Poster #442789. 2015 AIChE annual meeting, Salt Lake City, UT, November 8-13, 2015.<\/li>\n<li>Wang, K.-C.; Welter, J.; Rizzi de Freitas, L.; Aris, K.; Thomas, D.; Zhong, Y.; Egelhoff, T.; and Baskaran, H.: Inhibition of RhoA\/ROCK signaling enhances chondrogenesis in human mesenchymal stem cells. Poster #P1656. American Society for Cell Biology (ASCB) annual meeting, San Diego, CA, December 12-15, 2015.<\/li>\n<li>Mishra, R.; Sefcik, R.; Bishop, T.; Welter, J.F.; Caplan, A.I.; and Dean, D.: Proliferation and osteogenic differentiation of human mesenchymal stem cells on poly(propylene fumarate) tissue engineering scaffolds. MSC 2015, Cleveland, OH.<\/li>\n<li>Verbus, E.; Khalil, A.; Welter, J.; Caplan, A.; and Lee, Z.: Comparing reporters based on miRNA and marker-gene promoter for imaging MSC chondrogenesis. Poster #10. NCRM retreat Cleveland, OH, March 6, 2015.<\/li>\n<li>Wang, K.-C.; Welter, J.; and Baskaran, H.: Inhibition of rock expression directs human mesenchymal stem cells toward chondrogenesis. NCRM retreat Cleveland, OH, March 6, 2015.<\/li>\n<li>Prologo, J.D.; Duesler, L.; Berilla, J.; Baskaran, H.; Schluchter, M.; Corn, D; and Welter, J.: Effects of pressure and shear related to the needle delivery of stem cells. Society of Interventional Radiology 2013 (submitted)<\/li>\n<li>Heebner, J.; Chung, C.-Y.; Gu, M.; Welter, J.F.; and Mansour, J.M.: Prediction of storage, Young&#8217;s and aggregate moduli of agarose hydrogels as surrogates for tissue-engineered cartilage from ultrasonic measurement. NCRM retreat Cleveland, OH, December 2, 2013<\/li>\n<li>Prologo, J.D.; Duesler, L.; Berilla, J.; Baskaran, H.; Schluchter, M.; and Welter, J.: Effects of pressure and shear related to the needle delivery of stem cells. NCRM retreat Cleveland, OH, December 2, 2013<\/li>\n<li>Verbus, E.; Yuan, L.; Merry, C.; Khalil, A. Welter, J.; Caplan, A.; and Lee, Z.: Imaging chondrogenic differentiation with micro RNA. NCRM retreat Cleveland, OH, December 2, 2013<\/li>\n<li>Chung, C.-Y.; Heebner, J.E.; Duesler, L.D.; Mansour, J.M.; and Welter, J.F.: The feasibility of using ultrasound elastography to determine material properties of engineered cartilage in a sterile bioreactor. MSC2013, Cleveland, OH, August 19-21, 2013<\/li>\n<li>Heebner, J.; Chung, C.-Y.; Gu, M.; Welter, J.F.; and Mansour, J.M.: Prediction of storage, Young&#8217;s and aggregate moduli of agarose hydrogels as surrogates for tissue-engineered cartilage from ultrasonic measurement of speed of sound. MSC2013, Cleveland, OH, August 19-21, 2013<\/li>\n<li>Rivera, A.L.; Mulcahy, B.; Chou, C.-L.; Sakai, T.; Caplan, A.I.; Welter, J.F.; and Baskaran, H.: 3-Dimensional Osteochondral Tissue Engineering AIChE 2013, San Francisco, CA, November 3-8, 2013: 337618<\/li>\n<li>Chou, C.-L.; Rivera, A.L.; Sakai, T.; Drazba, J.; Caplan, A.I.; Goldberg, V.M.; Welter, J.F.; and Baskaran, H.: A multiscale approach to stem cell-based chondrogenesis for cartilage repair AIChE 2013, San Francisco, CA, November 3-8, 2013: 348582<\/li>\n<li>Wang, K.-C.; Welter, J.; Egelhoff, T.; Duesler, L.; and Baskaran, H.: Myosin-II modulates the differentiation of human mesenchymal stem cells toward a myogenic versus chondrogenic fate. Proceedings of the 2013 Research ShowCASE, Case Western Reserve University, Cleveland, OH. April 12, 2013<\/li>\n<li>Mott, E.; Belle, V.; Welter, J.; Lennon, D.; Duesler, L.; Wang, M.; Busso, M.; Wallace, J.; Bensusan, J.; Fisher, J.; Dean, D.; and Caplan, A.: Additive manufacturing of poly (propylene fumarate) scaffolds and bioreactor pre-culturing of canine mesenchymal stem cells for cranial tissue engineering. Proceedings of the 2013 Research ShowCASE, Case Western Reserve University, Cleveland, OH. April 12, 2013<\/li>\n<li>Mott, E.; Belle, V.; Welter, J.; Lennon, D.; Duesler, L.; Wang, M.; Busso, M.; Bensusan, J.; Fisher, J.; and Dean, D.: Additive manufacturing of poly (propylene fumarate) scaffolds and bioreactor pre-culturing of canine mesenchymal stem cells for cranial tissue engineering. 4th Annual National Center for Regenerative Medicine scientific retreat. Cleveland, OH November 12, 2012<\/li>\n<li>Larson, B.L.; Wu, P.B.; Estes, B.T.; Moutos, F.T.; Guilak, F.; Welter, J.F.; Langer, R.; and Freed, L.E.: &#8220;3D-woven poly (?-caprolactone) (PCL) with human mesenchymal stem cells (hMSCs): differentiation and integration with native bone in vivo&#8221; MRS 2012<\/li>\n<li>Welter, J.F.; Abdalian, S.; and Mansour, J.M.: Feasibility of using M-mode ultrasound imaging for cartilage tissue engineering quality control. BMES 2012<\/li>\n<li>Chou, C.L.; Rivera, A.L.; Caplan, A.; Goldberg, V.; Welter, J.F.; and Baskaran, H.: Multiscale approach to stem cell-based chondrogenesis for cartilage repair. ICRS; Montr\u00e9al, PQ, 2012<\/li>\n<li>Belle, V.; Wallace, J.; Welter, J.; Lennon, D.; Fisher, J.; Wang, M.; and Dean, D.: Bioreactor pre-culturing of human and canine mesenchymal stem cells on poly(propylene fumarate) bone scaffolds prepared by additive manufacturing. TERMIS NA 2011 (<em>accepted<\/em>)<\/li>\n<li>Sarkar, S.; Bustard, B.; Welter, J.F.; and Baskaran, H.: A Combined Experimental and Theoretical Approach to Model Cell-Cell Interactions In Cancer Cell Migration. AIChE, Minneapolis, MN, October 16 &#8211; 21, 2011<\/li>\n<li>Chou, C.-L.; Rivera, A.L.; Welter, J.F., and Baskaran, H.: Micrometer Scale Guidance of Mesenchymal Stem Cells to Form Structurally Oriented Cartilage Extracellular Matrix. AIChE, Minneapolis, MN, October 16 &#8211; 21, 2011<\/li>\n<li>Correa, D.; Welter, J.F.; Duesler, L.; and Caplan, A.I.: Fibroblast growth factors 18 and 9 regulate chondrogenic differentiation of human mesenchymal stem cells. OARSI World Congress on Osteoarthritis, San Diego, CA, September 15 &#8211; 18, 2011<\/li>\n<li>Welter, J.F.; Citak, M.; Baskaran, H.; Caplan, A.I.; Goldberg, V.M.; and Mansour, J.M.: Does acoustic homogeneity correlate with tissue quality in engineered cartilage? OARSI World Congress on Osteoarthritis, San Diego, CA, September 15 &#8211; 18, 2011<\/li>\n<li>Chou, C.L.; Rivera, A.L.; Caplan, A.; Goldberg, V.; Welter, J.F.; and Baskaran, H.: Microscale guidance for optimal human mesenchymal stem cell-based chondrogenesis. OARSI World Congress on Osteoarthritis, San Diego, CA, September 15 &#8211; 18, 2011<\/li>\n<li>Welter, J.F.; Yuan, L.; Lim, S.; Molter, J.; Duesler, L.; Caplan, A.I.; and Lee, Z.: Real time imaging of reporter gene expression in differentiating human mesenchymal stem cells. BMES, Hartford, CT, October 12 &#8211; 15, 2011<\/li>\n<li>Citak, M.; Baskaran, H.; Caplan, A.I.; Mansour, J.M.; and Welter, J.F.: acoustic homogeneity as a quality measure in tissue engineered cartilage. BMES, Hartford, CT, October 12 &#8211; 15, 2011<\/li>\n<li>Chou, C.L.; Rivera, A.L.; Caplan, A.; Goldberg, V.; Welter, J.F.; and Baskaran, H.: Microscale guidance effect on stem cell based chondrogenesis for cartilage repair. BMES, Hartford, CT, October 12 &#8211; 15, 2011<\/li>\n<li>Sarkar, S.; Bustard, B.L.; Welter, J.F.; and Baskaran, H.: Combined experimental and mathematical approach to study microfabrication-based cell migration. BMES 2011 BMES, Hartford, CT, October 12 &#8211; 15, 2011<\/li>\n<li>B\u00fck\u00fclmez, H.; Bartels, C.; Nanda, K.; Haqqi, T.M.; and Welter, J.F.: Cartilage protective effects of C-type natriuretic peptide over-expression in a K\/BxN TCR arthritis model. ACR\/ARHP 2011 Pediatric Rheumatology Symposium (PRSYM) Miami, FL, June 2 &#8211; 5, 2011.<\/li>\n<li>Dean, D.; Penick, K.J.; Anka, A.; Lennon, D.P.; Caplan, A.I.; and Welter, J.F.: Optimization of canine MSC osteogenesis by timed growth factor combinations. TERMIS-NA 2010<\/li>\n<li>Abrahamsson, C.K; Yang, F.; Park, H.; Brunger, J.M.; Valonen, P.K.; Langer, R.; Welter, J.F.; Caplan, A.I; Guilak, F.; Freed, L.E.: Influence of medium supplements on chondrogenesis and osteogenesis of collagen-embedded hMSCs on 3D-woven scaffolds. Gordon Research Conference on Musculoskeletal Biology and Bioengineering, 2010<\/li>\n<li>Chou, C.-L.; Rivera, A.L.; Penick, K.; Caplan, A.I.; Goldberg, V.M.; Welter, J.F.; and Baskaran, H.: Microscale guidance and its effect on human mesenchymal stem cell alignment and chondrogenesis. BMES 2010.<\/li>\n<li>Penick, K.J.; Baskaran, H.; Berilla, J.A.; and Welter, J.F.: Measuring glucose consumption by chondrogenically differentiating mesenchymal stem cells. BMES 2010.<\/li>\n<li>Richey, T.; Smith, M.; Thanoo, B.; Penick, K.J.; and Welter, J.F: Microsphere-based delivery of betamethasone to differentiating human mesenchymal stem cells. BMES 2010<\/li>\n<li>Walker, J.; Mansour, J.M.; Caplan, A.I.; Goldberg, V.M.; and Welter, J.F.: Poroelastic material properties of hydrogels and cartilage evaluated using ultrasound. BMES 2010<\/li>\n<li>Welter, J.F.; Solchaga, L.A.; Penick, K.J.; Leahy, P.; Caplan, A.I.; and Goldberg, V.M.: Gene expression changes associated with chondrogenic differentiation of human mscs. OARSI 2010<\/li>\n<li>Chou, C.-L.; Rivera, A.L.; Penick, K.J.; Caplan, A.I.; Goldberg, V.M.; Welter, J.F.; and Baskaran, H.: Microscale guidance and its effect on human mesenchymal stem cell alignment and chondrogenesis. OARSI 2010<\/li>\n<li>B\u00fck\u00fclmez, H.; Haqqi, T.; Khan, F.; Welter, J.F.; and Murakami, S.:.Role of c-type natriuretic peptide (cnp) in osteogenesis and treatment of osteoporosis. OARSI 2010<\/li>\n<li>Walker, J.; McKee, A.; Berilla, J.; Baskaran, H.; Mansour, J.; and Welter, J.F.: Nondestructive ultrasonic evaluation of mechanical properties of agarose gels. ORS 2010<\/li>\n<li>Chou, C.-L.; Rivera, A.L.; Welter, J.F.; and Baskaran, H.: Micrometer scale guidance of mesenchymal stem cells to form structurally oriented extracellular matrix. ORS 2010<\/li>\n<li>Shao, Y.; Wang, L.; Welter, J.F.; and Ballock, R.T.: Primary cilia are required for ihh signal transduction in response to hydrostatic loading of growth plate chondrocytes. ORS 2010<\/li>\n<li>McKee, A.; Mansour, J.M.; and Welter, J.F.: Noninvasive evaluation of mechanical properties of agarose gels using ultrasound technology. BMES 2009<\/li>\n<li>Berilla, J. and Welter, J.F.: Time-constant based fluorescent oxygen sensor. BMES 2009<\/li>\n<li>Welter, J.F.; Pelyak, M.R.; Penick, K.J.; Solchaga, L.A.; and Goldberg, V.M.: Extracellular matrix deposition by chondrogenically differentiating human mesenchymal stem cells is enhanced by macromolecular crowding. OARSI World Congress on Osteoarthritis, Montr\u00e9al, PQ Canada September 9-13, 2009<\/li>\n<li>Pelyak, M.; Penick, K.; Cheung, H.-M.; and Welter, J.: Accelerated MSC extracellular matrix deposition through dextran sulfate, polystyrene, and hyaluronic acid. MSC2009, August 17-19, 2009<\/li>\n<li>Chou, C.-L.; Rivera, A.L.; Welter, J.F.; and Baskaran, H.: Micrometer scale guidance of mesenchymal stem cells to form structurally oriented extracellular matrix. AICHE 2009 (Accepted)<\/li>\n<li>Berilla, J. and Welter, J.F.: Oxygen sensors for bioreactor monitoring. Proceedings of the 2009 Research ShowCASE, Case Western Reserve University, Cleveland, OH. 2009<\/li>\n<li>McKee, A.M.; Mansour, J.M.; and Welter, J.F.: Noninvasive evaluation of mechanical properties through the use of ultrasound technology. Proceedings of the 2009 Research ShowCASE, Case Western Reserve University, Cleveland, OH. 2009<\/li>\n<li>Pelyak, M.; Penick, K.; Cheung, H.M.; and Welter, J.F.: Accelerated MSC extracellular matrix deposition through dextran sulfate polystyrene, and hyaluronic acid. Proceedings of the 2009 Research ShowCASE, Case Western Reserve University, Cleveland, OH. 2009<\/li>\n<li>Welter, J.F.; Solchaga, L.A.; Leahy, P.; Penick, K.J.; Caplan, A.I.; Goldberg, V.M.: Gene expression patterns during chondrogenic differentiation of human MSCs. 55th Annual Meeting of the Orthop\u00e6dic Research Society, Las Vegas, NV, February, 2009. 924.<\/li>\n<li>Pelyak, M.R.; Penick, K.J.; Berilla, J.A.; Solchaga, L.A.; and Welter, J.F.: Macromolecular crowding accelerates extracellular matrix deposition by differentiating MSCs. 55th Annual Meeting of the Orthop\u00e6dic Research Society, Las Vegas, NV, February, 2009. 914.<\/li>\n<li>Valonen, P.K.; Moutos, F.T.; Kusanagi, A.; Moretti, M.; Diekman, B.O.; Welter, J.F.; Caplan, A.I.; Guilak, F.; and Freed, L.E.: In vitro generation of mechanically functional cartilage grafts based on adult human stem cells and 3D woven poly(?-caprolactone) scaffolds. 55th Annual Meeting of the Orthop\u00e6dic Research Society, Las Vegas, NV, February, 2009. 934.<\/li>\n<li>Shao, Y.; Wang, L.; Welter, J.; Ballock, R.T.; Leiferman, E.; and Noonan, K.: Mechanical forces modulate indian hedgehog signaling in vitro and in vivo. 55th Annual Meeting of the Orthop\u00e6dic Research Society, Las Vegas, NV, February, 2009. 993<\/li>\n<li>Welter, J.F.; Solchaga, L.A.; Leahy, P.; Penick, K.J.; Caplan, A.I.; Goldberg, V.M.: Database of gene expression patterns during chondrogenic differentiation of human MSCs. OARSI 2008 (<em>accepted<\/em>).<\/li>\n<li>Baskaran, H.; Kienitz, B. L.; Liang, W.-H.; Penick, K.; Welter, J. F.: Optimizing collagen-GAG scaffolds for tissue engineering applications. OARSI 2008 (<em>accepted<\/em>).<\/li>\n<li>Berilla, J and Welter, J.F.: Local thickness measurements in engineered cartilage using image analysis. BMES meeting 2008, (<em>accepted<\/em>)<\/li>\n<li>Berilla, J and Welter, J.F.: Image analysis algorithm for measuring local thickness in engineered cartilage. Proceedings of the 7th Annual meeting workshop of the Midwestern Tissue Engineering Consortium, April 11-12, University of Cincinnati, Cincinnati, OH. 2008:nnn<\/li>\n<li>Berilla, J and Welter, J.F.: Image analysis algorithm for measuring local thickness in engineered cartilage. Research ShowCase2008<\/li>\n<li>Shao, Y.Y.; Welter, J.F.; Wang, L.; and Ballock, R.T.: Response of growth plate chondrocytes to hydrostatic loading in vitro. 54th Annual Meeting of the Orthopaedic Research Society, San Francisco, CA, 638, March 2-5, 2008.<\/li>\n<li>Welter, J.F.; Baskaran, H.; Solchaga, L.A.; Penick, K.; and Berilla, J.: Aggregate formation dynamics as a biomarker for chondrogenic potential of mesenchymal stem cells. BMES 2007 P5.166<\/li>\n<li>Welter, J.F.; Baskaran, H.; Solchaga, L.A.; Penick, K.; and Berilla, J.: Aggregate formation dynamics as a biomarker for chondrogenic potential of mesenchymal stem cells. MSC2007, August 27-29, 2007:224<\/li>\n<li>Shao, Y.; Welter, J.; Wang, L.; and Ballock, T.: Hydrostatic loading of growth plate chondrocytes. ASBMR 2007 Journal of Bone and Mineral Research, 22S1:S156<\/li>\n<li>Berilla, J.; Penick, K.; Solchaga, L.; and Welter, J.: Timing of aggregate formation as a biomarker for chondrogenic potential. Proceedings of the 6th Annual meeting workshop of the Midwestern Tissue Engineering Consortium, April 20-21, 2007<\/li>\n<li>Penick, K., Solchaga, L.A.; and Welter, J.F.: A simplified aggregate culture system to assess chondrogenic potential. Proceedings of the 6th Annual meeting workshop of the Midwestern Tissue Engineering Consortium, April 20-21, 2007<\/li>\n<li>Berilla, J.; Penick, K.; Solchaga, L.; and Welter, J.: Timing of aggregate formation as a biomarker for chondrogenic potential. Proceedings of the 2007 Research ShowCASE, Case Western Reserve University, Cleveland, OH. 2007:102<\/li>\n<li>Penick, K., Solchaga, L.A.; and Welter, J.F.: A simplified aggregate culture system to assess chondrogenic potential. Proceedings of the 2007 Research ShowCASE, Case Western Reserve University, Cleveland, OH. 2007: 284<\/li>\n<li>Berilla, J.; Penick, K.; Solchaga, L.; and Welter, J.: Timing of aggregate formation as a biomarker for chondrogenic potential. Proceedings of the 2007 Research ShowCASE, Case Western Reserve University, Cleveland, OH. 2007:72<\/li>\n<li>Penick, K., Solchaga, L.A.; and Welter, J.F.: A simplified aggregate culture system to assess chondrogenic potential. Proceedings of the 2007 Research ShowCASE, Case Western Reserve University, Cleveland, OH. 2007<\/li>\n<li>Davood, V.; Welter, J.F.; Jackowe, D.J.; George, J.E.; Wang, J.Y. and Fisher, J.P.: Loading Rapid-Prototyped, Tissue-Engineered Poly(propylene fumarate) Scaffolds for Bioreactor Culturing. Proceedings of the 2007 Research ShowCASE, Case Western Reserve University, Cleveland, OH. 2007<\/li>\n<li>Solchaga, L.A.; Penick, K.J.; Caplan, A.C.; Goldberg, V.M.; and Welter, J.F.: Transforming growth factor-beta 1 modulates lineage progression of human mesenchymal stem cell-derived chondrocytes. Transactions of the Orthop\u00e6dic Research Society, 2007, 32:1504<\/li>\n<li>Welter, J.F.; Solchaga, L.A.; Berilla, J.A.; Anderson, R.; Penick, K.J.; Vinson, A.; and Baskaran, H.: Measuring and modelling substrate mass-transport and consumption during human mesenchymal stem cell-based cartilage tissue engineering. Transactions of the Orthop\u00e6dic Research Society, 2007, 32:494<\/li>\n<li>Welter, J.F.; Baskaran, H.; Solchaga, L.A.; and Goldberg, V.: Modelling substrate mass-transport during mesenchymal stem cell-based cartilage tissue engineering OARSI World Congress on Osteoarthritis Prague, Czech Republic December 7-10, 2006<\/li>\n<li>Solchaga, L.A.; Penick, K.; Caplan, A.I.; Goldberg, V.M.; and Welter, J.F.: Transforming growth factor-beta 1 modulates lineage progression of human mesenchymal stem cell-derived chondrocytes. OARSI World Congress on Osteoarthritis Prague, Czech Republic December 7-10, 2006<\/li>\n<li>Welter, J.F.; Anderson, R.; Penick, K.; Solchaga, L.A.; and Baskaran, H.: Substrate mass-transport modelling during MSC-based chondrogenesis Biomedical Engineering Society meeting, Chicago, IL, October 11 &#8211; October 14, 2006<\/li>\n<li>Anderson, R.; Baskaran, H.; Berilla, J.; Solchaga, L.; Penick, K.; and Welter, J.: Modeling mass-transport during maturation of MSC-based tissue engineered cartilage. Proceedings of the 2006 Research ShowCASE, Case Western Reserve University, Cleveland, OH. 2006:133<\/li>\n<li>Baskaran, H.; Kienitz, B.; and Welter, J.: Suspension centrifugation for optimizing lyophilized collagen-gag scaffolds for tissue engineering. Proceedings of the 2006 Research ShowCASE, Case Western Reserve University, Cleveland, OH. 2006:63<\/li>\n<li>Solchaga, L.; Penick, K.J.; Goldberg, V.M.; Caplan, A.I.; and Welter, J.F.: Regulation of hypertrophic differentiation of human mesenchymal stem cell-derived chondrocytes. Proceedings of the 2006 Research ShowCASE, Case Western Reserve University, Cleveland, OH. 2006:408<\/li>\n<li>Vinson, A.; Solchaga, L.; Penick, K.; Welter, J.F.; and Baskaran, H.: Assessment of mass transport limitations in mesenchymal stem cell-based spherical cartilage constructs. Proceedings of the 2006 Research ShowCASE, Case Western Reserve University, Cleveland, OH. 2006:42<\/li>\n<li>Anderson, R.W.; Baskaran, H.; Berilla, J.A.; Solchaga, L.A.; Penick, K.J.; and Welter, J.F.: Modeling substrate mass transport during the growth of an MSC-based cartilage construct. Proceedings of the 6th symposium of the International Cartilage Repair Society, San Diego, CA, 8 &#8211; 11 January 2006: P3-40<\/li>\n<li>Solchaga, L.A.; Penick, K.J.; Goldberg, V.M.; Caplan, A.I.; Welter, J.F.: Regulation of lineage progression of human mesenchymal stem cell-derived chondrocytes. Proceedings of the 6th symposium of the International Cartilage Repair Society, San Diego, CA, 8 &#8211; 11 January 2006: P4-51<\/li>\n<li>Berilla, J.A.; Solchaga, L.A.; Baskaran, H.; and Welter, J.F.: A modular bioreactor optimized for cartilage tissue engineering. Biomedical Engineering Society meeting, Baltimore, MD, September 28 &#8211; October 1, 2005, 277:15<\/li>\n<li>Berilla, J.A.; Solchaga, L.A.; Penick, K.; Baskaran, H.; and Welter, J.F.: A modular bioreactor system for cartilage tissue engineering. Proceedings of the Arthritis Research Conference, Atlanta, GA. 2005<\/li>\n<li>Solchaga, L.A.; Penick, K.; Porter, J.D.; Goldberg, V.M.; Caplan, A.I.; Welter, J.F.: FGF-2 enhances the mitotic and chondrogenic potentials of human adult bone marrow-derived mesenchymal stem cells. Proceedings of the Arthritis Research Conference, Atlanta, GA. 2005<\/li>\n<li>Baskaran, H.; Berilla, J.; Solchaga, L.; and Welter, J.F.: Mesenchymal stem cell-based cartilage tissue engineering. Proceedings of the Arthritis Research Conference, Atlanta, GA. 2005<\/li>\n<li>Burton, L.; Penick, K.; Welter, J.F.; Caplan, A.I.; Goldberg, V.M.; and Solchaga, L.A.: Fibroblast growth factor-2 enhances the chondrogenic differentiation of adult mesenchymal stem cells. Proceedings of the 2005 Research ShowCASE, Case Western Reserve University, Cleveland, OH. 2005:169<\/li>\n<li>Berilla, J.; Solchaga, L.A.; Penick, K.; Baskaran, H.; and Welter, J.F.: A modular bioreactor system for cartilage tissue engineering Proceedings of the 2005 Research ShowCASE, Case Western Reserve University, Cleveland, OH. 2005:324<\/li>\n<li>Baskaran, H.; Berilla, J.; Solchaga, L.; and Welter, J.F.: Mesenchymal stem cell-based cartilage tissue engineering Proceedings of the 2005 Research ShowCASE, Case Western Reserve University, Cleveland, OH. 2005:50<\/li>\n<li>Welter, J.F.; Solchaga, L.A.; Penick, K.; Baskaran, H.; Goldberg, V.M.; Caplan, A.I.; and Berilla, J.A.: A modular bioreactor system for cartilage tissue engineering. Transactions of the Orthop\u00e6dic Research Society, 2005, 30(2):1771<\/li>\n<li>Wenger, R.; Welter, J.F.; Hans, M.G.; Malemud, C.J.: Hydrostatic pressure increases apoptosis in tissue-engineered cartilage-constructs. Osteoarthritis Cartilage 12 Supplement B, S73, 2004<\/li>\n<li>Baskaran, H.; Solchaga, L.; Berilla, J.; and Welter, J.: Mesenchymal stem cell based cartilage tissue engineering. American Institute of Chemical Engineers meeting, Austin, TX, November 7-12, 2004:75c<\/li>\n<li>Baskaran, H.; Solchaga, L.; Berilla, J.; and Welter, J.: Transport considerations in mesenchymal stem cell-based cartilage tissue engineering. Biomedical Engineering Society meeting, Philadelphia, PA, October 13-16, 2004, 971:44<\/li>\n<li>Welter, J.; Baskaran, H.; Berilla, J.; Penick, K.; Goldberg, V.; Mansour, J.; Caplan, A.; and Solchaga, L.: Expansion and differentiation environment modulates chondrogenesis in large tissue engineered constructs. Biomedical Engineering Society meeting, Philadelphia, PA October 13-16, 2004972:44<\/li>\n<li>Welter, J.; Baskaran, H.; Berilla, J.; Penick, K.; Goldberg, V.; Mansour, J.; Caplan, A.; and Solchaga, L.: Enhanced chondrogenesis in large tissue engineered constructs by modulation of growth and differentiation conditions. Proceedings of the 5th symposium of the International Cartilage Repair Society, Ghent, Belgium, May 26 &#8211; 29, 2004:625<\/li>\n<li>Baskaran, H.; Solchaga, L.; Berilla, J.; and Welter, J.: Assessment of mass transport limitations during cartilage tissue engineering. Proceedings of the 5th symposium of the International Cartilage Repair Society, Ghent, Belgium, May 26 &#8211; 29, 2004:653<\/li>\n<li>Baskaran, H.; Solchaga, L.A.; Berilla, J.; and Welter, J.F.: Assessment of mass transport limitations during cartilage tissue engineering. Proceedings of the 2004 Research ShowCASE, Case Western Reserve University, Cleveland, OH. 2004:212<\/li>\n<li>Solchaga, L.A.; Goldberg, V.M.; Mishra, R.; Caplan, A.I.; Penick, K.J.; and Welter, J.F.: FGF-2 enhances the mitotic and chondrogenic potentials of human adult mesenchymal stem cells. Proceedings of the 2004 Research ShowCASE, Case Western Reserve University, Cleveland, OH. 2004:447<\/li>\n<li>Welter, J.F.; Baskaran, H.; Berilla, J.; Penick, K.; Goldberg, V.M.; Mansour, J.; Caplan, A.I.; and Solchaga, L.: Modulation of growth and differentiation conditions enhances chondrogenesis in large tissue engineered constructs. Proceedings of the 2004 Research ShowCASE, Case Western Reserve University, Cleveland, OH. 2004:448<\/li>\n<li>Welter, J.F.; Baskaran, H.; Berilla, J.; Penick, K.; Mansour, J.; Caplan, A.I.; and Solchaga, L.: Modulation of growth and differentiation conditions enhances chondrogenesis in large tissue engineered constructs. Transactions of the Orthop\u00e6dic Research Society, 2004, 29(2):719<\/li>\n<li>Baskaran, H.; Solchaga, L.A.; Berilla, J.; and Welter, J.F.: Assessment of mass transport limitations during cartilage tissue engineering. Transactions of the Orthop\u00e6dic Research Society, 2004, 29(2):721<\/li>\n<li>Solchaga, L.A.; Goldberg, V.M.; Mishra, R.; Caplan, A.I.; and Welter, J.F.: FGF-2 modifies the gene expression profile of bone marrow-derived human mesenchymal stem cells. Transactions of the Orthop\u00e6dic Research Society, 2004, 29(2):777<\/li>\n<li>Welter, J.F.; Penick, K.; Berilla, J.; Caplan, A.I.; Goldberg, V.M.; and Solchaga, L.A.: MSC-based tissue engineered cartilage: Effects of construct assembly method and perfusion rates. Proceedings of the Arthritis Research Conference, Keystone, CO. 2003:71<\/li>\n<li>Baskaran, H.; Solchaga, L.A.; Penick, K.; Berilla, J.; and Welter, J.F.: Substrate mass transport in tissue engineered cartilage. Proceedings of the Arthritis Research Conference, Keystone, CO. 2003:70<\/li>\n<li>Welter, J.F.; Solchaga, L.; and Berilla, J.: Design of a modular bioreactor system. Proceedings of the 2003 Research ShowCASE, Case Western Reserve University, Cleveland, OH. 2003:69<\/li>\n<li>Penick, K.; Berilla, J.; Solchaga, L.; and Welter, J.F.: On the use of Delrin\u00ae (acetal) in tissue culture. Proceedings of the 2003 Research ShowCASE, Case Western Reserve University, Cleveland, OH. 2003:41<\/li>\n<li>Baskaran, H.; Solchaga, L.A.; Penick, K.; Berilla, J.; and Welter, J.F.: Substrate mass transport in tissue engineered cartilage. Proceedings of the 2003 Research ShowCASE, Case Western Reserve University, Cleveland, OH. 2003:67<\/li>\n<li>Berilla, J.; Solchaga, L.; and Welter, J.F.: A multichannel fiberoptic spectrophotometer for monitoring bioreactor medium pH. Proceedings of the 2003 Research ShowCASE, Case Western Reserve University, Cleveland, OH. 2003:247<\/li>\n<li>Malemud, C.; Islam, N.; Haqqi, T.; Jepsen, K.; Kraay, M.; Welter, J.F.: and Goldberg, V.: Role of apoptosis in arthritis. Proceedings of the 2003 Research ShowCASE, Case Western Reserve University, Cleveland, OH. 2003:24<\/li>\n<li>Solchaga, L.A.; Goldberg, V.M.; Mansour, J.; Caplan, A.I.; and Welter, J.F.: Cartilage tissue engineering: In vitro generation of large cartilaginous constructs. Transactions of the Orthop\u00e6dic Research Society, 2003, 28(2):944<\/li>\n<li>Welter, J.F.; Tognana, E.; Goldberg, V.M.; Caplan, A.I.; and Solchaga, L.A.: Assembly of large cell-scaffold composites for cartilage tissue engineering. Transactions of the Orthop\u00e6dic Research Society, 2003, 28(2):949<\/li>\n<li>Solchaga, L.A.; Tognana, E.; Goldberg, V.M.; Caplan, A.I.; and Welter, J.F.: Tissue engineered cartilage implants: in vitro chondrogenic pre-conditioning. Proceedings of the 4th symposium of the International Cartilage Repair Society, Toronto \/ CA, 15 &#8211; 18 June 2002:271<\/li>\n<li>Welter, J.F.; Tognana, E.; Mansour, J.; Goldberg, V.M.; Caplan, A.I.; and Solchaga, L.A.: Tissue engineered cartilage implants: in vitro chondrogenic preconditioning. Proceedings of the 2nd Annual workshop of the Midwestern Tissue Engineering Consortium, 2002:21<\/li>\n<li>Solchaga, L.; Tognana, E.; Goldberg, V.M.; Caplan, A.I.; and Welter, J.F.: Tissue engineered cartilage implants: optimizing construct assembly. Transactions of the Orthop\u00e6dic Research Society, 2002, 27(1):483<\/li>\n<li>Welter, J.F.; Pradhan, S.; Tsurel, S.; and Berilla, J.: Modulation of the c-fos promoter activity by brief low amplitude strains: a role for ets transcription factors? Transactions of the Orthop\u00e6dic Research Society, 2002, 27(2):522<\/li>\n<li>Tsurel, S.; Pradhan, S.; Berilla, J.; and Welter, J.F.: Response of osteoblasts to brief, low amplitude strains: modulation of c-fos promoter activity. Israel Orthopaedic Association, Tel Aviv, December 4-5, 2001. J. Bone Joint Surg., 84-B(Supll. III):316-317<\/li>\n<li>Solchaga, L.A.; Tognana, E.; and Welter, J.F.: Tissue engineered cartilage implants: optimizing construct assembly. Orthop\u00e6dic Research Day, Case Western Reserve University, June 2001<\/li>\n<li>Berilla, J. and Welter, J.F.: Development of a Shear Sensor for Cell Culture Applications. Orthop\u00e6dic Research Day, Case Western Reserve University, June 2001<\/li>\n<li>Pradhan, S.; Berilla, J.; Tsurel, S.; and Welter, J.F.: Response of osteoblasts to brief, low amplitude strains: Modulation of c-fos promoter activity. Orthop\u00e6dic Research Day, Case Western Reserve University, June 2001<\/li>\n<li>Malemud, C.J.; Haqqi, T.M.; Jepsen, K.J.; Islam, N.; Kraay, M.; Welter, J.; and Goldberg, V.M.: Induction of apoptosis in human chondrocytes by hydrostatic pressure. Osteoarthritis and Cartilage 2001, 9(Supplement B):S8<\/li>\n<li>Pradhan, S.; Tsurel, S.; Berilla, J.; and Welter, J.F.: Response of the c-fos promoter to brief low amplitude strains in osteoblasts: a role for ets transcription factors? ASBMR 2001 J. Bone Miner. Res. 2001, 16(S1):S361<\/li>\n<li>Balasubramanian, S.; Agarwal, C.; Efimova, T.; Dubyak, G.; Banks, E.B.; Welter, J.F.; and Eckert. R.L.: Thapsigargin suppresses differentiation-dependent human involucrin promoter activity by reducing CCAAT\/enhancer-binding protein &#8211; DNA binding. 62nd Annual Meeting of the Society for Investigative Dermatology, Washington, DC, May, 2001<\/li>\n<li>Tsurel, S. and Welter, J.F.: Physiological levels of mechanical strain modulate osteoblast differentiation in vitro. Orthopaedic Research Day, Case Western Reserve University, January 2000<\/li>\n<li>Islam, N.; Islam, S.; Haqqi, T.; and Welter, J.F.: EGCG inhibits chondrocyte apoptosis. Orthop\u00e6dic Research Day, Case Western Reserve University, January 2000<\/li>\n<li>Welter, J.F.; Islam, N.; Islam, S.; and Haqqi, T.M.: EGCG &#8211; a constituent of green tea &#8211; inhibits chondrocyte apoptosis. Transactions of the Orthop\u00e6dic Research Society 2000, 25(2):907<\/li>\n<li>Agarwal, C.; Effimova, T.; Welter, J.F.; Crish, J.F.; and Eckert, R.L.: CCAAT\/Enhancer binding proteins &#8211; required regulators of human involucrin promoter activity. Journal of Investigative Dermatology 1999, 112(4):549<\/li>\n<li>Effimova, T.; LaCelle, P.T.; Welter, J.F.; and Eckert, R.L.: Regulation of human involucrin promoter activity via a specific MAPK signal transduction cascade. Journal of Investigative Dermatology 1999, 112(4):549<\/li>\n<li>Effimova, T.; LaCelle, P.T.; Welter, J.F.; and Eckert, R.L.: Regulation of human involucrin promoter activity by a PKC, RAS, MEKK1, MEK3, p38\/RK, AP1 signal transduction pathway. Proceedings of the AACR 1999, 40:364<\/li>\n<li>Tsurel, S.; Goldberg, V.M.; and Welter, J.F.: The response of human mesenchymal stem cells to mechanical strains changes as a function of differentiation state. Transactions of the Orthop\u00e6dic Research Society, 1999, 24(2):628<\/li>\n<li>Banks, E.B.; Crish, J.F.; Welter, J.F.; and Eckert, R.L.: Characterization of human involucrin promoter distal regulatory region transcriptional activator elements &#8211; a role for SP1 and AP1 binding sites. Journal of Investigative Dermatology 1998, 110(4):604<\/li>\n<li>Efimova, T.; Banks, E.B.; LaCelle, P.T.; Welter, J.F.; and Eckert, R.L.: Regulation of human involucrin promoter activity by a protein kinase C, Ras, MEKK, and Activator Protein-1 signal transduction pathway. Journal of Investigative Dermatology 1998, 110(4):604<\/li>\n<li>Welter, J.F.; Agarwal, C.; Efimova, T.; and Eckert, R.L.: The human involucrin promoter proximal regulatory region &#8211; a role for C\/EBP, AP1, ets, and AP2 binding sites. Journal of Investigative Dermatology 1998, 110(4):603<\/li>\n<li>Welter, J.F. and Eckert, R.L.: Functional characterization of the human involucrin proximal promoter regulatory region &#8211; Effects of CAAT enhancer binding protein, activator protein &#8211; 1, ETS factors and activator protein &#8211; 2. Journal of Investigative Dermatology 1997, 108(4):630<\/li>\n<li>Welter, J.F.; Robinson, N.A.; Bright, G.R.; and Eckert, R.L.: Immunocytochemical localization of AP1 family transcription factors in normal human keratinocytes cultured under serum free conditions. Journal of Investigative Dermatology 1997, 108(4):630<\/li>\n<li>Robinson, N.A.; Lapic, S.; Welter, J.F.; and Eckert, R.L.: S100c, s100a10, annexin I, desmosomal proteins, sprs, plasminogen activator inhibitor &#8211; 2, and involucrin are components of the cornified envelope of cultured human epidermal keratinocytes. Journal of Investigative Dermatology 1997, 108(4):552<\/li>\n<li>Welter, J.F.; Gali, H.U.; Crish, J.F.; and Eckert, R.L.: Regulation of the human involucrin promoter by POU domain proteins. Journal of Investigative Dermatology 1996, 106(4):907<\/li>\n<li>Banks, E.B.; Crish, J.F.; Welter, J.F.; and Eckert, R.L.: Combinatorial regulation of human involucrin promoter activity by modulator, silencer and enhancer elements. Journal of Investigative Dermatology 1996, 106(4):838<\/li>\n<li>Welter, J.F. and Eckert, R.L.: Expression of activator protein-1 (AP-1) family members in the human epidermis and in cultured keratinocytes. Journal of Investigative Dermatology 1995, 104(4):674<\/li>\n<li>Welter, J.F.; Crish, J.F.; Agarwal C.; and Eckert R.L.: Regulation of human involucrin promoter function by activator protein-1 (jun\/fos) and phorbol myristate acetate. Journal of Investigative Dermatology 1994, 102(4):577<\/li>\n<li>Brown, K.L.B. and Welter, J.F.: A comparison of vascularized and conventional bone grafts for bridging large bone defects. In: Proceedings of the Fourth International Symposium on Limb Salvage in Musculoskeletal Oncology. Springer Verlag<\/li>\n<li>Welter, J.F. and Brown, K.L.B.: A comparison of free vascularized and conventional fibular grafts for large defects in weight bearing bones. In: Aebi, M. and Regazzoni, P. (eds) Proceedings of the First International Symposium on Bone Transplantation: 1989, pp. 86 &#8211; 87. Springer Verlag<\/li>\n<li>Welter, J.F. and Brown, K.L.B.: A comparison of free vascularized and conventional fibular grafts for large defects in weight bearing bones. Orthop\u00e6dic Transactions 1987, 11(2):291 &#8211; 292<\/li>\n<li>Welter, J.F.; Kornacki, J.B.; and Brown, K.L.B.: A comparison of free vascularized and conventional fibular grafts for large defects in weight bearing bones. Transactions of the Orthop\u00e6dic Research Society, 1987, 22(1):115<\/li>\n<li>Brown, K.L.B.; Kornacki, J.B.; Welter, J.F.; Poole, A.R.; and Cruess, R.L.: The effects of weightbearing on the growth of heterotopically transplanted free vascularized epiphyseal grafts in dogs. Orthop\u00e6dic Transactions 1986, 10(2):241 &#8211; 242<\/li>\n<li>Brown, K.L.B.; Kornacki, J.B.; Welter, J.F.; and Cruess, R.L.: The effects of weight bearing on the growth of heterotopically transplanted free vascularized epiphysial grafts in dogs. Transactions of the Orthop\u00e6dic Research Society, 1986, 21(1):52<\/li>\n<\/ol>\n<p>&nbsp;<\/p>\n<h3>Invited Presentations:<\/h3>\n<ol>\n<li>Combined sliding shear and ultrasound evaluation demonstration. CTTE \u2013 2019 \u201cCell-Based Therapies and Tissue Engineering\u201d short course, Case Western Reserve University, Cleveland, OH, May 22, 2019.<\/li>\n<li>Joint flexion bioreactor demonstration. CTTE \u2013 2019 \u201cCell-Based Therapies and Tissue Engineering\u201d short course, Case Western Reserve University, Cleveland, OH, May 22, 2019.<\/li>\n<li>Combined sliding shear and ultrasound evaluation demonstration. CTTE \u2013 2018 \u201cCell-Based Therapies and Tissue Engineering\u201d short course, Case Western Reserve University, Cleveland, OH, May 23, 2018.<\/li>\n<li>Ultrasound applications in cartilage. Skeletal Research Center seminar series, Case Western Reserve University, Cleveland, OH, November 7, 2016<\/li>\n<li>Sounds Hard. Ultrasound applications in cartilage. Skeletal Research Center seminar series, Case Western Reserve University, Cleveland, OH, December 8, 2014.<\/li>\n<li>Cartilage Tissue Engineering. EBME 325 guest lecture, Case Western Reserve University, Cleveland, OH, November 5, 2012.<\/li>\n<li>Poking around in the viscosupplementation morass. Skeletal Research Center seminar series, Case Western Reserve University, Cleveland, OH, April 16, 2012.<\/li>\n<li>Canine and Human Mesenchymal Stem Cells, Growth Factors, Bioreactors, and Animal Model Studies. External Advisory Board and Co-Investigators meeting of NIH Grant R01-DE013740, Strength and Resorption of Biodegradable Skull Implants. July 21, 2011<\/li>\n<li>Intra-articular delivery of injectable sustained-release drug formulations. NCRM Retreat, November 14, 2011<\/li>\n<li>X marks the spot. Spatial and temporal distribution of Type X collagen in engineered cartilage. MSCs Skeletal Research Center seminar series, Case Western Reserve University, Cleveland, OH, November 15, 2010<\/li>\n<li>Canine Mesenchymal Stem Cells, Growth Factors, Bioreactors, and Toxicity. External Advisory Board and Co-Investigators meeting of NIH Grant R01-DE013740, Strength and Resorption of Biodegradable Skull Implants. June 2, 2010<\/li>\n<li>Crowding MSCs Skeletal Research Center seminar series, Case Western Reserve University, Cleveland, OH, February 1, 2010.<\/li>\n<li>Cartilage tissue engineering. EBME 325 guest lecture, Case Western Reserve University, Cleveland, OH, November 30, 2009<\/li>\n<li>Optimizing MSC differentiation; CTTE-2009 \u201cCell-Based Therapies and Tissue Engineering\u201d short course, Case Western Reserve University, Cleveland, OH, May 25, 2009<\/li>\n<li>How Thick Is That? Skeletal Research Center seminar series, Case Western Reserve University, Cleveland, OH, March 23, 2009<\/li>\n<li>Bioreactors for Cartilage Tissue Engineering; CTTE-2008 \u201cCell-Based Therapies and Tissue Engineering\u201d short course, Case Western Reserve University, Cleveland, OH, May 26, 2008<\/li>\n<li>Optimizing MSC differentiation; CTTE-2008 \u201cCell-Based Therapies and Tissue Engineering\u201d short course, Case Western Reserve University, Cleveland, OH, May 26, 2008<\/li>\n<li>Case study: Cartilage tissue engineering. EBME 325 guest lecture, Case Western Reserve University, Cleveland, OH, November 15, 2007<\/li>\n<li>Probing MSC differentiation. Skeletal Research Center seminar series, Case Western Reserve University, Cleveland, OH, October 29, 2007<\/li>\n<li>Heavy breathers: oxygen consumption in cartilage tissue engineering. Case Study: Cartilage Tissue engineering.<\/li>\n<li>Case study: Cartilage tissue engineering. EBME 325 guest lecture, Case Western Reserve University, Cleveland, OH, November 9, 2006<\/li>\n<li>Bioreactors for mesenchymal stem cell differentiation; CTTE-2006 Cell-Based Therapies and Tissue Engineering short course, Case Western Reserve University, Cleveland, OH, May 26, 2006<\/li>\n<li>Cartilage tissue engineering. Department of Biology seminar series. Case Western Reserve University, Cleveland, OH. May 4, 2006<\/li>\n<li>Bioreactors for mesenchymal stem cell differentiation; CTTE-2005 Cell-Based Therapies and Tissue Engineering short course, Case Western Reserve University, Cleveland, OH, June 1, 2005<\/li>\n<li>Surface characteristics of trabecular metal bone implants. Orthop\u00e6dic and Related Research Seminar series, Case Western Reserve University, Cleveland, OH, May 26, 2005<\/li>\n<li>Surface characteristics of bone implants. Skeletal Research Center seminar series, Case Western Reserve University, Cleveland, OH, November 29, 2004<\/li>\n<li>More cartilage tissue engineering &#8211; Design of a hydrostatic loading bioreactor. Skeletal Research Center seminar series, Case Western Reserve University, Cleveland, OH, March 15, 2004<\/li>\n<li>Cartilage tissue engineering. Skeletal Research Center seminar series. Case Western Reserve University, Cleveland, OH. March 10, 2003<\/li>\n<li>Cartilage tissue engineering. Orthop\u00e6dic grand rounds, Case Western Reserve University and University Hospitals of Cleveland, Cleveland, OH. February 22, 2003.<\/li>\n<li>Cartilage tissue engineering. Issues and approaches. CWRU\/CCF musculoskeletal research seminar series. Case Western Reserve University, Cleveland, OH, December 12, 2002<\/li>\n<li>Cartilage tissue engineering: Presented to the Arthritis Foundation Board of Trustees, Cleveland, OH, October 29, 2002<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p><strong>Research Associate Professor <\/strong><br \/>\n<strong>Skeletal Research Center, Department of Biology,<\/strong><br \/>\n<strong>Case Western Reserve University<\/strong><br \/>\n<strong>Millis Science Center, Room 114B<\/strong><br \/>\n<strong>2080 Adelbert Road<\/strong><br \/>\n<strong>Cleveland, Ohio 44106-7080<\/strong><br \/>\n<strong>Tel.: (216) 368-1333 (Office), (216) 368-2777 (Lab),<\/strong><br \/>\n<strong>Fax: (216) 368-4077<\/strong><br \/>\n<strong>E-mail: jfw2@cwru.edu<\/strong><\/p>\n<p><strong>October, 2019<\/strong><br \/>\nEducational Background:<\/p>\n<p>1996<br \/>\nPh.D. (Physiology &amp; Biophysics), Case Western Reserve University, Cleveland, OH, U.S.A.<\/p>\n<p>1990<br \/>\nM.Sc.\u00a0(Experimental\u00a0Surgery), Dean&#8217;s\u00a0Honors List McGill University, Montr\u00e9al,\u00a0Qu\u00e9bec,\u00a0<\/p>\n<p><a href=\"https:\/\/artsci.case.edu\/skeletal\/cv\/welter\/\" class=\"more-link\">Continue reading&#8230; <span class=\"screen-reader-text\">Jean Frederic Welter, M.D., M.Sc., Ph.D.<\/span><\/a><\/p>\n","protected":false},"author":19,"featured_media":0,"parent":125,"menu_order":0,"comment_status":"open","ping_status":"open","template":"","meta":{"spay_email":""},"_links":{"self":[{"href":"https:\/\/artsci.case.edu\/skeletal\/wp-json\/wp\/v2\/pages\/151"}],"collection":[{"href":"https:\/\/artsci.case.edu\/skeletal\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/artsci.case.edu\/skeletal\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/artsci.case.edu\/skeletal\/wp-json\/wp\/v2\/users\/19"}],"replies":[{"embeddable":true,"href":"https:\/\/artsci.case.edu\/skeletal\/wp-json\/wp\/v2\/comments?post=151"}],"version-history":[{"count":10,"href":"https:\/\/artsci.case.edu\/skeletal\/wp-json\/wp\/v2\/pages\/151\/revisions"}],"predecessor-version":[{"id":476,"href":"https:\/\/artsci.case.edu\/skeletal\/wp-json\/wp\/v2\/pages\/151\/revisions\/476"}],"up":[{"embeddable":true,"href":"https:\/\/artsci.case.edu\/skeletal\/wp-json\/wp\/v2\/pages\/125"}],"wp:attachment":[{"href":"https:\/\/artsci.case.edu\/skeletal\/wp-json\/wp\/v2\/media?parent=151"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}