Research Associate Professor
Skeletal Research Center, Department of Biology,
Case Western Reserve University
Millis Science Center, Room 114B
2080 Adelbert Road
Cleveland, Ohio 44106-7080
Tel.: (216) 368-1333 (Office), (216) 368-2777 (Lab),
Fax: (216) 368-4077
E-mail: jfw2@cwru.edu

October, 2019

Educational Background:

1996 Ph.D. (Physiology & Biophysics), Case Western Reserve University, Cleveland, OH, U.S.A.
1990 M.Sc. (Experimental Surgery), Dean’s Honors List McGill University, Montréal, Québec, Canada
1984 Permanent ECFMG certificate, Foreign Medical Graduate Examination in the Medical Sciences (F.M.G.E.M.S.)
1984 Doktor der gesamten Heilkunde (M.D.), School of Medicine, Leopold Franzens Universität, Innsbruck, Austria

 

Professional Experience:

2016 – Associate Director, Case Center for Multimodal Evaluation of Engineered Cartilage, Case Western Reserve University, Cleveland, OH
2007 – Research Associate Professor, Department of Biology Case Western Reserve University, Cleveland, OH
2012 – Research Associate Professor, Center for Regenerative Medicine, School of Medicine, Division of General Medical Sciences, Case Western Reserve University, Cleveland, OH (Secondary Appointment)
2004 – 2007 Senior Research Associate, Skeletal Research Center Case Western Reserve University, Cleveland, OH
1998 – 2004 Assistant Professor, Department of Orthopædics, Case Western Reserve University, Cleveland, OH
1996 – 1998 Instructor, Department of Orthopædics, Case Western Reserve University, Cleveland, OH
1990 – 1996 Ph.D. Candidate, Department of Physiology & Biophysics, Case Western Reserve University, Cleveland, OH
1989 – 1990 Post-Doctoral Fellow, Department of Orthopædics, Case Western Reserve University, Cleveland, OH
1988 – 1989 PGY-1 Surgery Resident, Surgery Residency Program, Case Western Reserve University, Cleveland, OH
1985 – 1988 Research Fellow, Montreal Children’s Hospital Research Institute (Orthopædic Research Laboratory), Montréal, PQ, Canada

 

Professional Affiliations:

2010 – Present Tissue Engineering and Regenerative Medicine International Society
2008 – Present Osteoarthritis Research Society International
2007 – Present Biomedical Engineering Society
2003 – Present International Cartilage Repair Society
2001 – Present American Society for Bone and Mineral Research
1998 – Present American Society for Biochemistry & Molecular Biology
1997 – 2014 Orthopædic Research Society
1989 – Present American Association for the Advancement of Science

 

Honors and Awards:

2006 ICRS poster award “Cum Laude”
2003, 2005 Arthritis Foundation travel ward
1991 – 1993 Research Fellowship, Cell Physiology Training Program. Department of Physiology & Biophysics, Case Western Reserve University, Cleveland, OH
1990 McGill University, Dean’s Honors List
1989 – 1990 Research Fellowship, NIH Training Program in Musculoskeletal Research. Department of Orthopædics, Case Western Reserve University, Cleveland, OH
1985 – 1988 Fellow of the McGill University – Montreal Children’s Hospital Research Institute

 

Teaching Experience:

High school
2019 Cheyenne Jones, Hathaway Brown, student advisor
2013 Jake Althans, Gilmour Academy student co-advisor
2012 Sarah Abdalian, Gilmour Academy student co-advisor
Undergraduate
2018 – Kareem Akabashoroun, work study student/web assistant
2017 Hanna Chan, undergraduate project co-advisor (MAE)
2014-2016 Joe Heebner, undergraduate project co-advisor (MAE)
2013-2016 Joe Heebner, ENGAGE fellowship sponsor
2013 Marine Gu, M.Sc. co-advisor and committee member
2011 Marine Gu, undergraduate senior project co-advisor
2011 Eduardo Arellano, summer laboratory project co-advisor
2010 – 2011 Marcin Citak, undergraduate senior project co-advisor
2009 Jason Walker, summer undergraduate student
Graduate
2014 – Yi Zhong, MSc guidance committee member (BME)
2009 – present Thesis committee for Shiv Shanmugan, Vinay Sethia, Pavan Sethia, Balambal Subramanian, Hong Wang, and JT Tan: MS in Entrepreneurial Biotechnology Program.
2008 – 2009 Ashley McKee, undergraduate senior project co-advisor
2008 Michael Pelyak, ENGAGE fellowship sponsor
2006 – 2012 EBME 325, Introduction to Tissue Engineering, guest lecturer. Department of Biomedical Engineering, CWRU
2005 – 2006 Ross Anderson, undergraduate senior project co-advisor
1991 – 1994 Introduction to Microcomputers. Department of Physiology & Biophysics, CWRU
Fellows
2016 – Mostafa Motavalli, Ph.D., Postdoctoral Fellow
2014 – Johnathan Kenyon, Ph.D., Postdoctoral Fellow
2003 – 2004 Mukund Deglurkar, M.B.B.S., M.S., F.R.C.S. Research Fellow, MD candidate, University of Wales
2003 – 2004 Reid Wenger, D.D.S., Research Fellow
2002 Rabia Ahmed, summer undergraduate student.
1997 – 1998 Shmuel Tsurel, M.D.; Research Fellow
Other
2005 – 2008 Bioreactors for MSC differentiation; “Cell-Based Therapies and Tissue Engineering” (CTTE) short course

 

Funded Research:

  • Administrative Supplement to NIH/NIBIB P41 EB 021911, CWRU center for multi-modal evaluation of engineered cartilage (Caplan, PI), 09/01/2018 – 03/31/2019. Project Co-director
  • NIH/NIBIB P41 EB 021911, CWRU center for multi-modal evaluation of engineered cartilage (Caplan, PI), 06/01/2016 – 03/31/2021. Project Co-director
  • NIH/NIAMS R21 proposal, Cartilage repair by condensed mesenchymal stem cell delivery via collagen fabric. 2017 – 2019. Co-Investigator
  • AFIRM II Project CF-03. 12/01/2013-11/30/2018. Subproject co-investigator
  • NIH/NIBIB R01 EB 20367, CWRU center for multi-modal evaluation of engineered cartilage (Caplan, PI), 08/01/2014 – 07/31/2016. Project Co-director
  • IRT/Procaps: Pre-clinical Cytogel-MSC 2015 – 2016 Co-PI
  • AFIRM II 2014 – 2017 subproject co-investigator.
  • Intra-articular delivery of injectable sustained-release microsphere drug formulations. CSCRM/BRCP: 7/1/09 – 6/30/2012. Principal Investigator
  • Tissue engineered cartilage repair. (PI: Arnold Caplan) NIH/NIAMS-NIBIB P01 AR053622 7/01/08 – 06/30/10 Core director and sub-project Co-principal investigator
  • Mechanisms of chondroprotection by pomegranate fruit extract R01 AT003627-01A1 PI: Tariq Haqq i7/1/2007 – 6/30/2012 Co-investigator.
  • Engineering cartilage: an integrated approach to biological joint repair. NIH R01 AR050802. 4/5/2005 – 3/31/2010. Principal investigator.
  • Chondrogenic preconditioning of cell/scaffold constructs for the repair of large cartilage defects. Arthritis Foundation Biomedical Research Grant. 07/01/2002 – 06/30/2005. Principal investigator.
  • Clinical tissue engineering center (CTEC), BRTT, PI: George Muschler, 04/01/2005 – 03/31/2008 Co-investigator.
  • Tissue-engineered skin with built-in capillary flow networks. NIH R01 EB006203. PI: Harihara Baskaran, 03/01/2006 – 02/28/2010, Co-investigator.
  • Tissue engineering of cartilage subtypes. NIH R01 DE015322. PI: James Dennis, 08/01/2004 – 7/31/2008, Co-investigator.
  • Strength and resorption of biodegradable skull implants. NIH R01-DE13740. PI: David Dean, Co-investigator. Start date pending. Co-investigator.
  • Effects of processing techniques for tantalum trabecular bone implant surfaces. Zimmer, Inc. PI: Victor Goldberg, 07/01/2003 – 06/30/2005, Co-investigator.
  • State-of-the-Art pH Monitoring in Bioreactors. NSF STTR Phase I. PI: John Robecheck, 07/01/03 – 06/30/04, Co-investigator.
  • Tissue engineered implants for cartilage regeneration. Ohio Board of Regents/Case Western Reserve University Presidential Research Initiative. 01/01/2001 – 12/31/2002. Principal investigator
  • Gene transcription in mechanically loaded bone cells. NIH R03 AR 45777. 10/1/1998 – 9/30/2001. Principal investigator

Pending/Planned Proposals:

  • NIH: Optimization of MSC chondrogenesis for articular cartilage tissue engineering (Caplan, PI). Co-investigator
  • NIH: Smart tooth platform technology (Yu, PI). Co-investigator
  • NIH: Cartilage repair by condensed MSC delivery (Akkus, PI). Co-investigator
  • NIH: Stimulus to compensatory renal growth. (Hostetter, PI). Co-investigator

Ongoing Collaborations:

At Case Western Reserve University:

  • Russel Wang, D.D.S, M.S.D.: PEEK for maxillofacial reconstruction
  • Andrew Rollins, Ph.D.: Optical coherence tomography of cartilage
  • Thomas Hostetter, M.D.: Compensatory renal growth.
  • Xiong (Bill) Yu, Ph.D.: Smart tooth platform.
  • David Prologo, M.D.: Intervertebral disc MSC injections.
  • Ozan Akkus, Ph.D.: Osteochondral tissue engineering.
  • Joseph Mansour, Ph.D.: Mechanical and ultrasound evaluation of hydrogels and engineered tissue.
  • Arnold Caplan, Ph.D.: Mesenchymal stem-cell based cartilage tissue engineering.
  • Davood Varghai: Cranial explant organ culture
  • David Prologo: Intradisc MSC injections
  • Harihara Baskaran: Mass transport studies in tissue-engineered cartilage and skin. Metabolic engineering of anaerobic bacteria.
  • Charles Malemud: Apoptosis in OA.
  • Victor Goldberg: Porous ingrowth bone implants, bone grafts and bone graft substitutes.
  • David Dean: Tissue engineering of cranial implants.
  • Tariq Haqqi: Oxidative stress and MSC performance.
  • C.C. Liu: Glucose consumption by differentiating mesenchymal stem cells

Off Campus:

  • Riccardo Gottardi (Pittsburgh) Mechanically active bioreactors
  • Pete Alexander (Pittsburgh) Osteochondral tissue engineering
  • Lisa Freed (MIT) and
  • Farshid Guilak (Washington U.): Osteochondral tissue engineering
  • Hülya Bükülmez, M.D.(MetroHealth): Role of CNP in MSC differentiation.
  • Olcay Jones (Walter Reed): MSCs in Lupus and Rheumatoid Arthritis
  • David Dean (Ohio State): Tissue engineering of cranial implants
  • Tracey Richey/Mark Smith (Oakwood Labs): Sustained-release intra-articular drug delivery
  • H. Michael Cheung (University of Akron): Dynamic light scattering in molecular crowding.
  • Lisa Freed (Massachusetts Institute of Technology): Cartilage tissue engineering.
  • John Robecheck, (Sensirox, Inc), Jay Johnson (UDRI): Development of micro-pH sensors.
  • R. Tracy Ballock, (Cleveland Clinic Foundation): Investigation of Heuter-Volkmann effect in vitro using a hydrostatic bioreactor.
  • Dwayne Bisgrove, Ph.D., System Biosciences (SBI): Lentiviral reporter/selection vectors to report cell differentiation.

Service to Professional Community:

  • 2017 – present Reviewer, Science Foundation Ireland
  • 2013 – present Reviewer, NMRC (Singapore) Clinician Scientist Awards
  • 2012 – present International Expert Panel member. National Medical Research Council (Singapore)
  • 2013 Ad hoc member, NIH Cell Culture Bioreactor Study Section ZRG1 IDM-M (30)
  • 2013 Reviewer NMRC (Singapore) Clinician Scientist Awards
  • 2012 – 2014 International Expert Panel member. National Medical Research Council (Singapore)
  • 2012 Member, NIH COBRE renewal review panel
  • 2011 Study section member for Arthritis Research UK
  • 2010, 2011 Reviewer, NCRM pilot grant proposals
  • 2009 Moderator, Progenitors and Stem Cells session, Orthopaedic Research Society meeting, Las Vegas, NV
  • 2009 Member, NIH Challenge Grant Review Panel #10, ZRG1 BDA-A (58) R
  • 2008, 2011 Member, Arthritis Research Campaign (U.K.) study section
  • 2008 Member, Special Emphasis Panel/Scientific Review Group 2009/01 MTE
  • 2008 Ad hoc member, NIH Special Emphasis Panel/Scientific Review Group ZAR1 EHB-H (M1) 1
  • 2006, 2007 Ad hoc member, NIH Special Emphasis Panel/Scientific Review Group ZAR1 EHB-J (M1) (1)
  • 2005 Ad hoc member, NIH Special Emphasis Panel/Scientific Review Group ZAR1 EHB-G (O1) (1)
  • 2005 Judge, MTEC-2005 presentation awards
  • 2004, 2006-2012 Ad hoc reviewer for the National Medical Research Council (Singapore) study section
  • 2004, 2006, 2007 Judge, graduate student poster competition at Research ShowCASE
  • 2003 Organizing committee for the 5th Bone Fluid Flow Workshop, Cleveland, OH. September 17 – 18
  • 2002 – 2003 Ad hoc member, NIH biomedical engineering study section ZRG1 SSS-M 58
  • 2001 – 2004 Member, Department of Orthopædics Research Committee
  • * Ad hoc reviewer for Acta Biomaterialia
  • * Ad hoc reviewer for Arthritis Research and Therapy
  • * Ad hoc reviewer for Biomaterials
  • * Ad hoc reviewer for BioTechniques
  • * Ad hoc reviewer for Bone
  • * Ad hoc reviewer for British Journal of Cancer
  • * Ad hoc reviewer for Cells, Tissues, Organs
  • * Ad hoc reviewer for Current Eye Research
  • * Ad hoc reviewer for Genomics
  • * Ad hoc reviewer for the Journal of Biological Chemistry
  • * Ad hoc reviewer for the Journal of Biomedical Materials Research
  • * Ad hoc reviewer for the Journal of Investigative Dermatology
  • * Ad hoc reviewer for the Journal of Orthopædic Research
  • * Ad hoc reviewer for the Orthopædic Research Society
  • * Ad hoc reviewer for Tissue Engineering
  • * Ad hoc reviewer for Yonsei Medical Journal

Patents:

  • Mansour, J.M.; Motavalli, M.; and Welter, J.F.: Method to rapidly detect shear-induced damage in tissue engineering cartilage, Provisional patent application number 62/539,793 filed August 2017.
  • Holt, V.; Welter, J.F.; Berilla, J.A.; Harris, M.; and Caplan, A.I.: Cell capture apparatus and staining device. Provisional patent application number 61/875918 filed September 10, 2013.
  • Welter, J.F.; Solchaga, L.A.; Berilla, J.A.; and Penick, K.: Apparatus and method for tissue engineering. US Patent # 8,507,266 issued August 13, 2013.

Publications:

Manuscripts Submitted/in Preparation:

  1. Motavalli, M.; Berilla, J.; Schluchter, M.; Welter, J.F; and Mansour, J.: Rapid evaluation of articular cartilage anisotropy using ultrasound. (submitted)
  2. Prologo, J.D.; Duesler, L.; Berilla,J.A.; Baskaran, H.; Schluchter, M.D.; and Welter, J.F.: Impact of concurrent pressure and shear on MSC viability and differentiation during simulated intervertebral disk needle injection. Journal of Vascular and Interventional Radiology 2014, (Submitted)
  3. Solchaga, L.A.; Penick, J.; Goldberg, V.M.; Caplan, A.I; and Welter, J.F.: TGF-β1 and dexamethasone regulate hypertrophy during chondrogenic differentation of bone marrow-derived mesenchymal stem cells (in preparation)
  4. Berilla, J.; Solchaga, L.A.; Baskaran, H.; and Welter, J.F.: Design of a cartilage tissue engineering bioreactor (submitted)
  5. Liang, W.H.; Janakiraman, V.; Welter, J.F.; and Baskaran, H.: Composite tissue engineered skin constructs made of collagen dermal analogs and cultured keratinocyte epidermal analogs (in preparation)
  6. Berilla, J. and Welter, J.F.: Image analysis algorithm for measuring local thickness (in revision)
  7. Welter, J.F.; Baskaran, H.; Berilla, J.A.; Caplan, A.I; Goldberg, V.M.; Penick, K.; and Solchaga, L.A.: Transient aggregate culture enables human mesenchymal stem cell-based cartilage tissue engineering (in preparation)
  8. Welter, J.F.: Simplified color thresholding of histological images using color-space rotation. (in preparation)
  9. Welter, J.F. and Mansour, J.M.: Evaluation of tissue engineered cartilage (in preparation)

Peer-Reviewed Manuscripts:

  1. Dai, Y.; Somoza, R.A.; Wang, L.; Welter, J.F.; Li, Y.; Caplan, A.I.; Liu, C.C.: Exploring the trans-cleavage activity of CRISPR Cas12a for the development of a universal electrochemical biosensor. Angewandte Chemie, 2019 doi: 10.1002/ange.201910772, PMID: 31568601 Abstract
  2. Larson, B.L.; Yu, S.N.; Park, H.; Estes, B.T.; Moutos, F.T.; Bloomquist, C.J.; Wu, P.B.; Welter, J.F.; Langer, R.; Guilak, F.; and Freed, L.E.: Cartilaginous and osteochondral tissue formation by human mesenchymal stem cells on three-dimensionally woven scaffolds. Journal of Tissue Engineering and Regenerative Medicine, 2019 PMID: 31115161, DOI: 10.1002/term.2899 Abstract
  3. Mansour, J.M.; Motavalli, M.; Dennis, J.E.; Kean, T.J.; Caplan, A.I.; Berilla, J.A.; and Welter, J.F.: Rapid detection of shear-induced damage in tissue engineered cartilage using ultrasound. Tissue engineering, part C, 2018, 24(8):443-456. PMID: 29999475, PMCID: PMC6088252. Abstract
  4. Zhong, Y.; Motavalli, M.; Caplan, A.I.; Welter, J.F.; and Baskaran, H.: Dynamics of intrinsic glucose uptake kinetics in human mesenchymal stem cells during chondrogenesis. Annals of Biomedical Engineering, 2018, 46:1896-1910. PMID: 29948374, PMCID: PMC6204100. Abstract
  5. Wang, K-C.; Egelhoff, T.T.; Caplan, A.I.; Welter, J.F.; Baskaran, H.: ROCK Inhibition promotes development of chondrogenic tissue by improved mass transport, Tissue Engineering Part A, 2018, 24:1218-1227. PMID: 29397789, PMCID: PMC6080111. Abstract
  6. Chou, C.-L.; Rivera, A.L.; Williams, V.; Welter, J.F.; Mansour, J.M.; Drazba, J.A.; Sakai, T.; and Baskaran, H.: Micrometer scale guidance of mesenchymal stem cells to form structurally oriented large-scale tissue engineered cartilage Acta Biomaterialia 2017, 60:210-219. PMID: 28709984, PMCID: PMC5581212. Abstract
  7. Verbus, E.A.; Kenyon, J.D.; Sergeeva, O.; Awadallah, A.; Yuan, L.; Welter, J.F.; Caplan, A.I.; Schluchter, M.D.; Khalil, A.M.; and Lee, Z.: Expression of miR-145-5p during chondrogenesis of mesenchymal stem cells Journal of Stem Cell Research (Overl Park) 2017, 1(3):1-10. PMID: 29721552, PMCID: PMC5926818. Abstract
  8. Mishra, R.; Sefcik, R.S.; Bishop, T.J.; Montelone, S.M.; Crouser, N.; Welter, J.F.; Caplan, A.I.; and Dean, D.: Growth factor dose tuning for bone progenitor cell proliferation and differentiation on resorbable poly(propylene fumarate) scaffolds. Tissue Engineering Part C Methods. 2016 22(9):904-913. Abstract
  9. Mansour, J.; Lee, Z.; and Welter, J.: Nondestructive techniques to evaluate the characteristics and development of engineered cartilage. (Invited review). Annals of Biomedical Engineering 2016 44(3):733-49. Abstract
  10. Chung, C.Y.; Heebner, J.; Baskaran, H.; Welter, J.F.; and Mansour, J.M.: Ultrasound elastography for estimation of regional strain of multilayered hydrogels and tissue-engineered cartilage. Ann Biomed Eng. 2015 43(12):2991-2300 Abstract 
  11. Mansour, J.M.; Gu, D.-W.; Chung, C.-Y.; Heebner, J.; Schluchter, M.D.; and Welter, J.F.: Towards the feasibility of using ultrasound to determine mechanical properties of tissues in a bioreactor. Annals of Biomedical Engineering 2014 42(10):2190-202 Abstract
  12. Correa, D.; Somoza, R.A.; Lin, P.; Greenberg, S.; Rom, E.; Duesler, L.; Welter, J.F.; Yayon, A.; and Caplan, A.I.: Sequential exposure to fibroblast growth factors (FGF) 2, 9 and 18 enhances hMSC chondrogenic differentiation. Osteoarthritis Cartilage. 2015 23(3):443-53. Abstract
  13. Somoza, R.; Welter, J.; Correa, D.; and Caplan, A.: Chondrogenic differentiation of Mesenchymal Stem Cells: unfulfilled expectations and new challenges. Tissue Engineering part B 2014, 20(6):596-608 PMID: 24749845, PMCID: PMC4241862Abstract
  14. Wallace, J.; Wang, M.O.; Thompson, P.; Busso, M.; Belle, V.; Mammoser, N.; Kim, K.; Fisher, J.P.; Siblani, A.; Xua, Y.; Welter, J.F.; Lennon, D.P.; Sun, J.; Mikos, A.G.; Caplan, A.I.; Dean, D.: Validating continuous digital light processing (cDLP) additive manufacturing accuracy and tissue engineering utility of a dye-initiator package. Biofabrication 2014 6(1) Abstract
  15. Welter, J.F.; Penick, J.; Solchaga, L.A.: Assessing adipogenic potential of mesenchymal stem cells: a rapid three-dimensional culture screening technique. Stem Cells International, 2013, Article ID 806525 Abstract
  16. Chou, C.-L.; Rivera, A.L.; Caplan, A.I.; Goldberg, V.M.; Welter, J.F.; and Baskaran, H.: Micrometer scale guidance of mesenchymal stem cells to form structurally oriented cartilage extracellular matrix. Tissue Engineering, Part A 2013, 19(9-10):1081 – 1090. Abstract
  17. Mansour, J.M. and Welter, J.F.: Multimodal evaluation of tissue-engineered cartilage. Journal of Medical and Biological Engineering 2013, 33(1):1-16 Abstract
  18. Shao, Y.; Wang, L.; Welter, J.F.; and Ballock, R.T.: Primary cilia modulate ihh signal transduction in response to hydrostatic loading of growth plate chondrocytes. Bone 2012, 50(1):79 – 84 Abstract
  19. Walker, J.M.; Myers, A.M.; Schluchter, M.D.; Goldberg, V.M.; Caplan, A.I.; Berilla, J.A.; Mansour, J.M.; and Welter, J.F.: Nondestructive Evaluation of Hydrogel Mechanical Properties Using Ultrasound. Annals of Biomedical Engineering 2011, 39(10):2521 – 2530Abstract
  20. Sarkar, S.; Bustard, B.L.; Welter, J.F.; and Baskaran, H.: Combined experimental and mathematical approach for development of microfabrication-based cancer migration assay. Annals of Biomedical Engineering 2011, 39(9):2346 – 2359. Abstract
  21. Auletta, J.J.; Zale, E.A.; Welter, J.; and Solchaga, L.: Fibroblast growth factor-2 enhances expansion of human bone marrow-derived mesenchymal stromal cells without diminishing their immunosuppressive potential. Stem Cells International 2011, Article ID 235176:1 – 10. Abstract
  22. Abrahamsson, C.A.; Yang, F.; Park, H.; Valonen, P.K.; Langer, R.; Welter, J.F.; Caplan, A.I.; Brunger, J.; Guilak, F.; Freed, L.E.: Chondrogenesis and mineralization during in vitro culture of human mesenchymal stem cells on 3D-woven scaffolds. Tissue Engineering, Part A 2010, 16(12):3709 – 3718). Abstract
  23. Liang, W.H.; Kienitz, B.L.; Penick, K.; Welter, J.F.; and Baskaran, H.: Optimizing collagen-GAG scaffolds for tissue engineering applications using centrifugation. Journal of Biomedical Materials Research, Part A 2010, 94(4):1050 – 1060.Abstract
  24. Valonen, P.K.; Moutos, F.T.; Kusanagi, A.; Moretti, M.; Diekman, B.O.; Welter, J.F.; Caplan, A.I.; Guilak, F.; and Freed, L.E: In vitro generation of mechanically functional cartilage grafts based on adult human stem cells and 3D-woven poly(ε-caprolactone) scaffolds. Biomaterials 2010, 31(8):2193 – 2200. Abstract
  25. Solchaga, L.A.; Penick, J.; Goldberg, V.M.; Caplan, A.I.; and Welter, J.F.: Fibroblast growth factor-2 enhances proliferation and delays loss of chondrogenic potential in human adult bone marrow-derived mesenchymal stem cells. Tissue Engineering 2009, (e-Pub ahead of print). Abstract
  26. Welter, J.F.; Solchaga, L.A.; and Penick, K.J.: Simplification of aggregate culture of human mesenchymal stem cells as a chondrogenic screening assay. BioTechniques 2007, 42(6):732 – 737. Abstract
  27. Henderson, J.H.; Welter, J.F.; Mansour, J.M.; Niyibizi, C.; Caplan, A.I; and Dennis, J.E.: Cartilage tissue engineering for pediatric laryngotracheal reconstruction: Comparison of chondrocytes from three anatomic locations in the rabbit. Tissue Engineering 2007, 13(4):843 – 853. Abstract
  28. Deglurkar, M.; Davy, D.T.; Goldberg, V.M.; Stewart, M.C.; and Welter, J.F.: Evaluation of machining methods for porous tantalum implants in a rabbit intramedullary osseointegration model. Journal of Biomedical Materials Research (B) 2007, 80B(2):528 – 540. Abstract
  29. Henderson, J.H.; Mansour, J.M.; Welter, J.F.; Awadallah, A.; Ginley, N.; Caplan, A.I.; and Dennis, J.E.: Cartilage tissue engineering: comparison of chondrocytes from three anatomic locations in the rabbit. CWRU Orthopaedic Journal 2006, 3(1):33- 42.
  30. Solchaga, L.A.; Tognana, E.; Penick, K.; Baskaran, H.; Caplan, A.I.; Goldberg, V.G.; and Welter, J.F.: A rapid vacuum-seeding technique for the assembly of large tissue-engineered cell/scaffold composites. Tissue Engineering 2006, 12(7):1851 – 1863. Abstract
  31. Wenger, R.; Hans, M.G.; Welter, J.F.; Solchaga, L.A.; Sheu, Y.R.; and Malemud, C.J.: Tissue-engineered human cartilage-constructs from human osteoarthritic chondrocytes. Frontiers in Biosciences, 2006, 11:1690 – 1695. Abstract
  32. Penick, K.J.; Solchaga, L.A.; and Welter, J.F.: A high-throughput aggregate culture system to assess the chondrogenic potential of mesenchymal stem cells. BioTechniques 2005, 39(5):687 – 691. Abstract
  33. Penick, K.; Berilla, J.; Solchaga, L.A.; and Welter, J.F.: Performance of polyoxymethylene plastic (POM) as a component of a tissue engineering bioreactor. Journal of Biomedical Materials Research 2005, 75(1):168 – 174. Abstract
  34. Solchaga, L.A.; Penick, K.; Porter, J.; Caplan, A.I.; Goldberg, V.M.; and Welter, J.F.: FGF-2 enhances the mitotic and chondrogenic potentials of human adult bone marrow-derived mesenchymal stem cells. J. Cellular Physiology 2005, 203:398 – 409. Abstract
  35. Solchaga, L.A.; Penick, K.; and Welter, J.F.: A manual mosaicking approach to generating large, high resolution digital images of histological sections. Proceedings of the Royal Microscopical Society 2004, 39(4):313 – 320.
  36. Stewart, M.C.; Welter, J.F.; and Goldberg, V.G.: Effect of Hydroxyapatite/Tricalcium-Phosphate coating on osseointegration of plasma-sprayed titanium alloy implants. Journal of Biomedical Materials Research 2004, 69A(1):1 – 10. Abstract
  37. Jabbour, L.; Welter, J.F.; Kollar, J.; and Hering, T.M.: Sequence, gene structure, and expression pattern of CNTL, a minor class intron-containing gene: evidence for a role in apoptosis. Genomics 2003, 81(3):292 – 303. Abstract
  38. Islam, N.; Haqqi, T.M.; Jepsen, K.J.; Kraay, M.; Welter, J.F.; Goldberg, V.M.; and Malemud, C.J.: Hydrostatic pressure induces apoptosis in human chondrocytes from osteoarthritic cartilage through up-regulation of tumor necrosis factor-α, inducible nitric oxide synthase, c-myc, p53 and bax-α, and suppression of bcl-2. Journal of Cellular Biochemistry 2002, 87: 266 – 278. Abstract
  39. Balasubramanian, S.; Agarwal, C.; Efimova, T.; Dubyak, G.R.; Banks, E.; Welter, J.; and Eckert, R.L.: Thapsigargin suppresses phorbol ester-dependent human involucrin promoter activity by suppressing CCAAT-enhancer-binding protein alpha (C/EBPα) DNA binding. Biochemical Journal 2000, 350(Pt 3):791 – 796. Abstract
  40. Agarwal, C.; Effimova, T.; Welter, J.F.; Crish, J.F.; and Eckert, R.L.: CCAAT/Enhancer-binding proteins. A role in regulation of human involucrin promoter response to phorbol ester. Journal of Biological Chemistry 1999, 274(10):6190 – 6194. Abstract
  41. Effimova, T.; LaCelle, P.; Welter, J.F.; and Eckert, R.L.: Regulation of human involucrin promoter activity by a protein kinase C, RAS, MEKK1, MEK3, P38/RK, AP-1 signal transduction pathway. Journal of Biological Chemistry 1998, 273(38):24387 – 24395. Abstract
  42. Banks, E.B.; Crish, J.F.; Welter, J.F.; and Eckert, R.L.: Characterization of human involucrin promoter distal regulatory region transcriptional activator elements – a role for SP1 and AP-1 binding sites. Biochemical Journal 1998, 331(Pt.1):61 – 69. Abstract
  43. Robinson, N.A.; Lapic, S.; Welter, J.F.; and Eckert, R.L.: S100A11, S100A10, annexin I, desmosomal proteins, SPRs, plasminogen activator inhibitor-2, and involucrin are components of the cornified envelope of cultured human epidermal keratinocytes. Journal of Biological Chemistry 1997, 272(18):12035 – 12046. Abstract
  44. Eckert R.L.; Crish J.F.; Banks E.B.; Welter, J.F.: The epidermis: genes on – genes off. Journal of Investigative Dermatology 1997, 109(4): 501 – 509. Abstract
  45. Eckert, R.L. and Welter, J.F.: Keratinocyte differentiation: genes and their regulation. Cell Death and Differentiation 1996, 3:373 – 383. Abstract
  46. Eckert, R.L. and Welter, J.F.: Transcription factor regulation of epidermal keratinocyte gene expression. Molecular Biology Reports 1996, 23:59 – 70. Abstract
  47. Welter, J.F.; Gali, H.U.; Crish, J.F.; and Eckert, R.L.: Regulation of human involucrin promoter activity by POU domain proteins. Journal of Biological Chemistry 1996, 271(25):14727 – 14733. Abstract
  48. Welter, J.F.; Crish, J.F.; Agarwal, C.; and Eckert, R.L.: Additions and corrections to: Fos related antigen (Fra-1), junB and junD activate human involucrin promoter transcription by binding to proximal and distal AP1 sites to mediate phorbol ester effects on promoter activity. Journal of Biological Chemistry 1996, 271(18):11034. PMID: 8662708
  49. Welter, J.F. and Eckert, R.L.: Differential expression of the fos and jun family members c-fos, fosB, fra-1, fra-2, c-jun, junB and junD during human epidermal differentiation. Oncogene 1995, 11(12):2681 – 2687. Abstract
  50. Welter, J.F.; Crish, J.F.; Agarwal, C.; and Eckert, R.L.: Fos related antigen (fra-1), junB and junD activate human involucrin promoter transcription by binding to proximal and distal AP1 sites to mediate phorbol ester effects on promoter activity. Journal of Biological Chemistry 1995, 270(21):12614 – 12622. Abstract
  51. Eckert, R.L.; Yaffe, M.B.; Crish, J.F.; Murthy, S.; Rorke, E.A.; and Welter, J.F.: Involucrin – Structure and role in envelope assembly. Journal of Investigative Dermatology 1993, 100(5):613 – 617. Abstract
  52. Welter, J.F.; Shaffer, J.W.; Stevenson, S.; Davy, D.T.; Field, G.A.; Klein L.; Li, X.Q.; Zika, J.M.; and Goldberg, V.M.: Cyclosporin A and tissue antigen matching in bone transplantation. Fibular allografts studied in the dog. Acta Orthopædica Scandinavica 1990, 61(6):517 – 527. Abstract

Book Chapters:

  1. Welter, J.F. and Baskaran, H.: Chapter 86 – Monitoring and Real-Time Control of Tissue Engineering Systems. In: Principles of tissue engineering, 5th edition, Lanza, R. ed. 2019 (invited Chapter, in press)
  2. Lee, Z.; Dennis, J.; Welter, J.; and Caplan, A.: Imaging stem cell differentiation for cell-based tissue repair. In: Methods in Enzymology: Imaging and Spectroscopy in Living Cells, Elsevier Publishing 2012 506:247-63. PMID: 22341228
  3. Welter, J.F.; Solchaga, L.A.; and Baskaran, H.: Chondrogenesis from human mesenchymal stem cells: Role of culture conditions. In: Hayat, E., ed.: Stem cells and cancer stem cells: Therapeutic applications in disease and injury, volume 5. Springer 2012:269 – 281 ISBN: 978-94-007-2899-8
  4. Solchaga, L.A.; Penick, K.J.; and Welter, J.F.: Chondrogenic differentiation of bone marrow-derived mesenchymal stem cells: tips & tricks. In: Vemuri, M.C.; Rao, M.S.; and Chase, L.G., eds.: Mesenchymal Stem Cell Assays and Applications. Humana Press, 2011, 698:253 – 278. Abstract
  5. Goldberg, V.M. and Welter, J.F.: Autografts. In: Callaghan, J.J.; Rosenberg, A.G.; and Rubash, H.E., eds.: The adult hip, Lippincott-Raven. 2006(23):304 – 328.
  6. Welter, J.F. and Goldberg, V.M.: Bone grafting and substitutes. In: Orthopædic knowledge update. AAOS, 2005:241 – 248.
  7. Solchaga, L.A.; Welter, J.F.; and Caplan, A.I.: Generation of pluripotent stem cells and their differentiation to the chondrocytic phenotype. In: Sabatini, M.; De Ceuninck, F.; and Pastoureau, P., eds.: Cartilage and osteoarthritis (Methods in Molecular Medicine series). Humana Press, 2004:53 – 68. Abstract
  8. Welter, J.F.; Solchaga, L.A.; and Stewart, M.C.: High efficiency non-viral transfection of chondrocytes. In: Sabatini, M.; De Ceuninck, F.; and Pastoureau, P., eds.: Cartilage and osteoarthritis (Methods in Molecular Medicine series). Humana Press, 2004:129 – 146. Abstract
  9. Solchaga, L.A.; Welter, J.F.; Caplan, A.I; and Goldberg, V.M.: Cartilage Tissue Engineering. In: Callaghan, J.J.; Rosenberg, A.G.; Rubash, H.E.; Simonian, P.T.; and Wickiewicz, T.L., eds.: The adult knee. Lippincott, Williams & Wilkins, Publishers, 2003:251 – 258.

Abstracts:

  1. Motavalli, M.; Blackburn, B.; Welter, J.; Mansour, J.; Rollins, A.: Optical coherence tomography analysis of articular cartilage under dynamic biaxial loads. TERMIS 2019, Orlando, FL, December 2-5, Poster 172 (accepted).
  2. Motavalli, M.; Jones, C.; Welter, J.F.; Berilla, J.; Li, M.; Schluchter, M.; Mansour, J.: Freeze-thaw cycling effects on articular cartilage anisotropy using ultrasound techniques TERMIS 2019, Orlando, FL, December 2-5, Presentation 118. (accepted).
  3. Zhang, B.; Zhong, Y.; Berilla, J.; Motavalli, M.; Welter, J.F.; Caplan, A.I.; Clark, K.L.; Pirosa, A.; Alexander, P.; and Baskaran, H.: Bioreactor development for joint segmentation model to investigate toxicants/teratogens. BMES 2019 Philadelphia, PA (accepted).
  4. Motavalli, M.; Blackburn, B.; Welter, J.F.; Mansour, J.M.; and Rollins, A.M.: Articular cartilage mechanical behavior under dynamic biaxial loads: optical coherence tomography analysis. BMES 2019 Philadelphia, PA (accepted).
  5. Motavalli, M.; Jones, C.; Welter, J.F.; Berilla, J.; Li, M.; Schluchter, M.; and Mansour, J.: Acoustic anisotropy of articular cartilage and effects of freeze-thaw cycling. BMES 2019 Philadelphia, PA (accepted).
  6. Zhong, Y.; Welsh, A.; Caplan, A.I.; Welter, J.F.; and Baskaran, H.: Essential amino acids metabolism during human mesenchymal stem cell chondrogenesis. BMES 2019 Philadelphia, PA (accepted).
  7. Jones, C.; Motavalli, M.; Berilla, J.; Mansour, J.; and Welter, J.F.: Evaluation of articular cartilage using ultrasound and anisotropic techniques. SEO 2019 poster session, Cleveland, OH, July 25, 2019. Poster # 24
  8. Welter, J.F.; Baskaran, H.; Mansour, J.M.; Somoza, R.A.; Lee, Z.; Khalil, A.; Li, M.; Huang, A.; Kenyon, J.; Motavalli, M.; and Caplan, A.I.: CWRU Center for Multimodal Evaluation of Engineered Cartilage. Proceedings of the 2019 Research ShowCASE, Poster 030. Case Western Reserve University, Cleveland, OH, April 19, 2019.
  9. Zhong, Y., Welter, J.F.; Caplan, A.I.; and Baskaran, H.: Biomolecular rate indicators of human mesenchymal stem cell chondrogenesis. Proceedings of the 2019 Research ShowCASE, Poster 286. Case Western Reserve University, Cleveland, OH, April 19, 2019.
  10. Motavalli, M.; Blackburn, B.; Welter, J.; Mansour, J.M.; Rollins, A.: Articular cartilage mechanical behavior under dynamic biaxial loads: Optical coherence tomography analysis. Proceedings of the 2019 Research ShowCASE, Poster 297. Case Western Reserve University, Cleveland, OH, April 19, 2019. (Mostafa Motavalli won first prize for post-doctoral poster presentations)
  11. Jones, C.; Motavalli, M.; Berilla, J.; Mansour, J.; and Welter, J.: Evaluation of freezing effects on articular cartilage using ultrasound techniques. Proceedings of the 2019 Research ShowCASE, Poster 454. Case Western Reserve University, Cleveland, OH. April 19, 2019.
  12. Blackburn, B.; Motavalli, M.; Ford, M.; Welter, J.; Mansour, J.; and Rollins, A.: Ex vivo measurement of biaxial strain distribution in articular cartilage with optical coherence tomography. 2019 SPIE Photonics West, San Francisco, CA, February 5-7.
  13. Zhong, Y.; Sivakumar, S.; Caplan, A.I.; Welter, J.F.; and Baskaran, H.: Secretome indicators of end tissue quality during human mesenchymal stem cell chondrogenesis. AIChE 2018 Pittsburgh, PA, October 28 – November 2, Paper 176h.
  14. Zhong, Y.; Sivakumar, S.; Caplan, A.I.; Welter, J.F.; and Baskaran, H.: Biomolecular rate indicators of human mesenchymal stem cell chondrogenesis. AIChE 2018 Pittsburgh, PA, October 28 – November 2, Paper 190h
  15. Zhong, Y.; Sivakumar, S.; Caplan, A.I.; Welter, J.F.; and Baskaran, H.: Biomolecular rate indicators for human mesenchymal stem cell chondrogenesis. BMES 2018, Atlanta, GA, October 17-20, Presentation Sa-3-15
  16. Motavalli, M.; Berilla, J.; Schluchter, M.; Welter, J.; and Mansour, J.: Evaluation of articular cartilage anisotropy using ultrasound technique. BMES 2018, Atlanta, GA, October 17-20, Poster FRI-181
  17. Blackburn, B.; Motavalli, M.; Rollins, A.; Welter, J.; and Mansour, J.: Optical coherence elastography for analysis of articular cartilage deformation under biaxial loads. BMES 2018, Atlanta, GA, October 17-20 Presentation Th-1-7
  18. Baskaran, H.; Motavalli, M.; and Welter, J.F.: CWRU Center for Multimodal Evaluation of Engineered Cartilage. Exhibitor booth # 200. BMES 2018, Atlanta, GA, October 17-20.
  19. Welter, J.F.; Baskaran, H.; Mansour, J.M.; Somoza, R.A.; Lee, Z.; Khalil, A.; Schluchter, M.D.; Huang, A.; Kenyon, J.; Motavalli, M.; and Caplan, A.I: CWRU Center for Multimodal Evaluation of Engineered Cartilage. A Biomedical Technology Resource Center funded by the National Institute of Biomedical Imaging and Bioengineering. Proceedings of the 2018 Research ShowCASE, Case Western Reserve University, Cleveland, OH. April 20, 2018.
  20. Motavalli, M.; Myers, J.; Huang, A.; Welter, J.; and Mansour, J.: 3D displacement fields in cartilage under compression using two-photon microscopy. Proceedings of the 2018 Research ShowCASE, Case Western Reserve University, Cleveland, OH. April 20, 2018.
  21. Zhong, Y.; Berilla, J.; Motavalli, M.; Welter, J.F.; Caplan, A.I.; Tuan, R.S.; Alexander, P.; and Baskaran, H.: Bioreactor for joint segmentation model to investigate toxicants/teratogens. Proceedings of the 2018 Research ShowCASE, Case Western Reserve University, Cleveland, OH. April 20, 2018.
  22. Motavalli, M.; Myers, J.; Huang, A.; Welter, J.; and Mansour, J.: 3D displacement fields in cartilage under compression using two-photon microscopy. Poster 511. TERMIS 2017 Charlotte, NC, December 3-6, 2017.
  23. Motavalli, M.; Berilla, J.; Dennis, J.; Caplan, A.; Mansour, J.; and Welter, J.: Using ultrasound for non-destructive evaluation of engineered cartilage damage by sliding shear. Poster 416. TERMIS 2017 Charlotte, NC, December 3-6, 2017.
  24. Zhong, Y.; Berilla, J.; Motavalli, M.; Welter, J.F.; Caplan, A.I.; Tuan, R.S.; Alexander, P.; and Baskaran, H.: Bioreactor for joint segmentation model to investigate toxicants/teratogens. Poster 594. TERMIS 2017 Charlotte, NC, December 3-6, 2017.
  25. Motavalli, M.; Zhong, Y.; Caplan, A.I; Welter, J.; and Baskaran, H.: Dynamics of intrinsic kinetics of glucose uptake during chondrogenesis. Presentation OP-TH-2-7. BMES 2017, Phoenix, AZ, October 11-14.
  26. Zhong, Y.; Pontius, W.D; Wang, K.-C.; Motavalli, M.; Caplan, A.I.; Welter, J.F.; and Baskaran, H.; Glucose metabolism during mesenchymal stem cell chondrogenesis. BMES 2017, Phoenix, AZ, October 11-14, poster P-TH-550
  27. Motavalli, M.; Berilla, J.; Dennis, J.; Caplan, A.; Mansour, J.; and Welter, J.: Non-destructive evaluation of engineered cartilage damage by sliding shear using ultrasound. Poster P-TH-298. BMES 2017, Phoenix, AZ, October 11-14.
  28. Motavalli, M; Myers, J.; Huang, A.; Welter, J.; and Mansour, J.: Determining 3D displacement fields in cartilage using two-photon microscopy. Presentation OP-SA-1-3. BMES 2017, Phoenix, AZ, October 11-14.
  29. Baskaran, H.; Motavalli, M.; and Welter, J.F.: CWRU Center for multimodal evaluation of engineered cartilage. BMES 2017, Phoenix, AZ, October 11-14, exhibitor booth #301.
  30. Sergeeva, O.; Kenyon, J.; Verbus, E.; Awadallah, A.; Welter, J.; Caplan, A.; Schluchter, M.; Khalil, A.; and Lee, Z.: Imaging chondrogenesis with miR-145-responsive reporter. 2017 World Molecular Imaging Congress, Philadelphia, PA, September 13-16. 2017. (Presented September 15).
  31. Wang, K.-C.; Kwan, E.; Aris, K.; Egelhoff, T.T.; Caplan, A.I.; Welter, J.F.; and Baskaran, H.: The effect of RhoA/ROCK signaling inhibition on the development of hMSC-based chondrogenic tissue. OARSI 2017 annual meeting, Las Vegas, NV, April 27-30, 2017.
  32. Zhong, Y.; Pontius, W.D.; Wang, K.-C.; Motavalli, S.; Caplan, A.I.; Welter, J.F.; and Baskaran, H.: Glucose metabolism during mesenchymal stem cell chondrogenesis. OARSI 2017 annual meeting, Las Vegas, NV, April 27-30, 2017.
  33. Welter, J.F.; Baskaran, H.; Mansour, J.M.; Somoza, R.; Lee, Z.; Khalil, A.; Schluchter, M.D.; Huang, A.; Kenyon, J.; Motavalli, M.; and Caplan, A.I.: CWRU Center for Multimodal Evaluation of Engineered Cartilage. A Biomedical Technology Resource Center Funded by the National Institute of Biomedical Imaging and Bioengineering. Proceedings of the 2017 Research ShowCASE, Case Western Reserve University, Cleveland, OH. April 21, 2017.
  34. Wang, K.-C.; Zhong, Y.; Thomas, D.; Egelhoff, T.; Caplan, A.I.; Welter, J.; and Baskaran, H.: Chondrogenic enhancement in human mesenchymal stem cells via RhoA/ROCK signaling inhibition. BMES annual meeting, Minneapolis, MN October 5-8, 2016.
  35. Zhong, Y.; Pontius, W.D.; Caplan, A.I.; Welter, J.F.; and Baskaran, H.: Use glucose metabolism as a predictive tool to study chondrogenesis in human mesenchymal stem cells. OARSI 2016 annual meeting Amsterdam, The Netherlands, March 31-April 3, 2016 (Poster #281).
  36. Pontius, W.; Zhong, Y.; Caplan, A.I.; Welter, J.F.; and Baskaran, H.: Using glucose metabolism as a predictive tool to study chondrogenesis in human mesenchymal stem cells. Poster #442789. 2015 AIChE annual meeting, Salt Lake City, UT, November 8-13, 2015.
  37. Wang, K.-C.; Welter, J.; Rizzi de Freitas, L.; Aris, K.; Thomas, D.; Zhong, Y.; Egelhoff, T.; and Baskaran, H.: Inhibition of RhoA/ROCK signaling enhances chondrogenesis in human mesenchymal stem cells. Poster #P1656. American Society for Cell Biology (ASCB) annual meeting, San Diego, CA, December 12-15, 2015.
  38. Mishra, R.; Sefcik, R.; Bishop, T.; Welter, J.F.; Caplan, A.I.; and Dean, D.: Proliferation and osteogenic differentiation of human mesenchymal stem cells on poly(propylene fumarate) tissue engineering scaffolds. MSC 2015, Cleveland, OH.
  39. Verbus, E.; Khalil, A.; Welter, J.; Caplan, A.; and Lee, Z.: Comparing reporters based on miRNA and marker-gene promoter for imaging MSC chondrogenesis. Poster #10. NCRM retreat Cleveland, OH, March 6, 2015.
  40. Wang, K.-C.; Welter, J.; and Baskaran, H.: Inhibition of rock expression directs human mesenchymal stem cells toward chondrogenesis. NCRM retreat Cleveland, OH, March 6, 2015.
  41. Prologo, J.D.; Duesler, L.; Berilla, J.; Baskaran, H.; Schluchter, M.; Corn, D; and Welter, J.: Effects of pressure and shear related to the needle delivery of stem cells. Society of Interventional Radiology 2013 (submitted)
  42. Heebner, J.; Chung, C.-Y.; Gu, M.; Welter, J.F.; and Mansour, J.M.: Prediction of storage, Young’s and aggregate moduli of agarose hydrogels as surrogates for tissue-engineered cartilage from ultrasonic measurement. NCRM retreat Cleveland, OH, December 2, 2013
  43. Prologo, J.D.; Duesler, L.; Berilla, J.; Baskaran, H.; Schluchter, M.; and Welter, J.: Effects of pressure and shear related to the needle delivery of stem cells. NCRM retreat Cleveland, OH, December 2, 2013
  44. Verbus, E.; Yuan, L.; Merry, C.; Khalil, A. Welter, J.; Caplan, A.; and Lee, Z.: Imaging chondrogenic differentiation with micro RNA. NCRM retreat Cleveland, OH, December 2, 2013
  45. Chung, C.-Y.; Heebner, J.E.; Duesler, L.D.; Mansour, J.M.; and Welter, J.F.: The feasibility of using ultrasound elastography to determine material properties of engineered cartilage in a sterile bioreactor. MSC2013, Cleveland, OH, August 19-21, 2013
  46. Heebner, J.; Chung, C.-Y.; Gu, M.; Welter, J.F.; and Mansour, J.M.: Prediction of storage, Young’s and aggregate moduli of agarose hydrogels as surrogates for tissue-engineered cartilage from ultrasonic measurement of speed of sound. MSC2013, Cleveland, OH, August 19-21, 2013
  47. Rivera, A.L.; Mulcahy, B.; Chou, C.-L.; Sakai, T.; Caplan, A.I.; Welter, J.F.; and Baskaran, H.: 3-Dimensional Osteochondral Tissue Engineering AIChE 2013, San Francisco, CA, November 3-8, 2013: 337618
  48. Chou, C.-L.; Rivera, A.L.; Sakai, T.; Drazba, J.; Caplan, A.I.; Goldberg, V.M.; Welter, J.F.; and Baskaran, H.: A multiscale approach to stem cell-based chondrogenesis for cartilage repair AIChE 2013, San Francisco, CA, November 3-8, 2013: 348582
  49. Wang, K.-C.; Welter, J.; Egelhoff, T.; Duesler, L.; and Baskaran, H.: Myosin-II modulates the differentiation of human mesenchymal stem cells toward a myogenic versus chondrogenic fate. Proceedings of the 2013 Research ShowCASE, Case Western Reserve University, Cleveland, OH. April 12, 2013
  50. Mott, E.; Belle, V.; Welter, J.; Lennon, D.; Duesler, L.; Wang, M.; Busso, M.; Wallace, J.; Bensusan, J.; Fisher, J.; Dean, D.; and Caplan, A.: Additive manufacturing of poly (propylene fumarate) scaffolds and bioreactor pre-culturing of canine mesenchymal stem cells for cranial tissue engineering. Proceedings of the 2013 Research ShowCASE, Case Western Reserve University, Cleveland, OH. April 12, 2013
  51. Mott, E.; Belle, V.; Welter, J.; Lennon, D.; Duesler, L.; Wang, M.; Busso, M.; Bensusan, J.; Fisher, J.; and Dean, D.: Additive manufacturing of poly (propylene fumarate) scaffolds and bioreactor pre-culturing of canine mesenchymal stem cells for cranial tissue engineering. 4th Annual National Center for Regenerative Medicine scientific retreat. Cleveland, OH November 12, 2012
  52. Larson, B.L.; Wu, P.B.; Estes, B.T.; Moutos, F.T.; Guilak, F.; Welter, J.F.; Langer, R.; and Freed, L.E.: “3D-woven poly (?-caprolactone) (PCL) with human mesenchymal stem cells (hMSCs): differentiation and integration with native bone in vivo” MRS 2012
  53. Welter, J.F.; Abdalian, S.; and Mansour, J.M.: Feasibility of using M-mode ultrasound imaging for cartilage tissue engineering quality control. BMES 2012
  54. Chou, C.L.; Rivera, A.L.; Caplan, A.; Goldberg, V.; Welter, J.F.; and Baskaran, H.: Multiscale approach to stem cell-based chondrogenesis for cartilage repair. ICRS; Montréal, PQ, 2012
  55. Belle, V.; Wallace, J.; Welter, J.; Lennon, D.; Fisher, J.; Wang, M.; and Dean, D.: Bioreactor pre-culturing of human and canine mesenchymal stem cells on poly(propylene fumarate) bone scaffolds prepared by additive manufacturing. TERMIS NA 2011 (accepted)
  56. Sarkar, S.; Bustard, B.; Welter, J.F.; and Baskaran, H.: A Combined Experimental and Theoretical Approach to Model Cell-Cell Interactions In Cancer Cell Migration. AIChE, Minneapolis, MN, October 16 – 21, 2011
  57. Chou, C.-L.; Rivera, A.L.; Welter, J.F., and Baskaran, H.: Micrometer Scale Guidance of Mesenchymal Stem Cells to Form Structurally Oriented Cartilage Extracellular Matrix. AIChE, Minneapolis, MN, October 16 – 21, 2011
  58. Correa, D.; Welter, J.F.; Duesler, L.; and Caplan, A.I.: Fibroblast growth factors 18 and 9 regulate chondrogenic differentiation of human mesenchymal stem cells. OARSI World Congress on Osteoarthritis, San Diego, CA, September 15 – 18, 2011
  59. Welter, J.F.; Citak, M.; Baskaran, H.; Caplan, A.I.; Goldberg, V.M.; and Mansour, J.M.: Does acoustic homogeneity correlate with tissue quality in engineered cartilage? OARSI World Congress on Osteoarthritis, San Diego, CA, September 15 – 18, 2011
  60. Chou, C.L.; Rivera, A.L.; Caplan, A.; Goldberg, V.; Welter, J.F.; and Baskaran, H.: Microscale guidance for optimal human mesenchymal stem cell-based chondrogenesis. OARSI World Congress on Osteoarthritis, San Diego, CA, September 15 – 18, 2011
  61. Welter, J.F.; Yuan, L.; Lim, S.; Molter, J.; Duesler, L.; Caplan, A.I.; and Lee, Z.: Real time imaging of reporter gene expression in differentiating human mesenchymal stem cells. BMES, Hartford, CT, October 12 – 15, 2011
  62. Citak, M.; Baskaran, H.; Caplan, A.I.; Mansour, J.M.; and Welter, J.F.: acoustic homogeneity as a quality measure in tissue engineered cartilage. BMES, Hartford, CT, October 12 – 15, 2011
  63. Chou, C.L.; Rivera, A.L.; Caplan, A.; Goldberg, V.; Welter, J.F.; and Baskaran, H.: Microscale guidance effect on stem cell based chondrogenesis for cartilage repair. BMES, Hartford, CT, October 12 – 15, 2011
  64. Sarkar, S.; Bustard, B.L.; Welter, J.F.; and Baskaran, H.: Combined experimental and mathematical approach to study microfabrication-based cell migration. BMES 2011 BMES, Hartford, CT, October 12 – 15, 2011
  65. Bükülmez, H.; Bartels, C.; Nanda, K.; Haqqi, T.M.; and Welter, J.F.: Cartilage protective effects of C-type natriuretic peptide over-expression in a K/BxN TCR arthritis model. ACR/ARHP 2011 Pediatric Rheumatology Symposium (PRSYM) Miami, FL, June 2 – 5, 2011.
  66. Dean, D.; Penick, K.J.; Anka, A.; Lennon, D.P.; Caplan, A.I.; and Welter, J.F.: Optimization of canine MSC osteogenesis by timed growth factor combinations. TERMIS-NA 2010
  67. Abrahamsson, C.K; Yang, F.; Park, H.; Brunger, J.M.; Valonen, P.K.; Langer, R.; Welter, J.F.; Caplan, A.I; Guilak, F.; Freed, L.E.: Influence of medium supplements on chondrogenesis and osteogenesis of collagen-embedded hMSCs on 3D-woven scaffolds. Gordon Research Conference on Musculoskeletal Biology and Bioengineering, 2010
  68. Chou, C.-L.; Rivera, A.L.; Penick, K.; Caplan, A.I.; Goldberg, V.M.; Welter, J.F.; and Baskaran, H.: Microscale guidance and its effect on human mesenchymal stem cell alignment and chondrogenesis. BMES 2010.
  69. Penick, K.J.; Baskaran, H.; Berilla, J.A.; and Welter, J.F.: Measuring glucose consumption by chondrogenically differentiating mesenchymal stem cells. BMES 2010.
  70. Richey, T.; Smith, M.; Thanoo, B.; Penick, K.J.; and Welter, J.F: Microsphere-based delivery of betamethasone to differentiating human mesenchymal stem cells. BMES 2010
  71. Walker, J.; Mansour, J.M.; Caplan, A.I.; Goldberg, V.M.; and Welter, J.F.: Poroelastic material properties of hydrogels and cartilage evaluated using ultrasound. BMES 2010
  72. Welter, J.F.; Solchaga, L.A.; Penick, K.J.; Leahy, P.; Caplan, A.I.; and Goldberg, V.M.: Gene expression changes associated with chondrogenic differentiation of human mscs. OARSI 2010
  73. Chou, C.-L.; Rivera, A.L.; Penick, K.J.; Caplan, A.I.; Goldberg, V.M.; Welter, J.F.; and Baskaran, H.: Microscale guidance and its effect on human mesenchymal stem cell alignment and chondrogenesis. OARSI 2010
  74. Bükülmez, H.; Haqqi, T.; Khan, F.; Welter, J.F.; and Murakami, S.:.Role of c-type natriuretic peptide (cnp) in osteogenesis and treatment of osteoporosis. OARSI 2010
  75. Walker, J.; McKee, A.; Berilla, J.; Baskaran, H.; Mansour, J.; and Welter, J.F.: Nondestructive ultrasonic evaluation of mechanical properties of agarose gels. ORS 2010
  76. Chou, C.-L.; Rivera, A.L.; Welter, J.F.; and Baskaran, H.: Micrometer scale guidance of mesenchymal stem cells to form structurally oriented extracellular matrix. ORS 2010
  77. Shao, Y.; Wang, L.; Welter, J.F.; and Ballock, R.T.: Primary cilia are required for ihh signal transduction in response to hydrostatic loading of growth plate chondrocytes. ORS 2010
  78. McKee, A.; Mansour, J.M.; and Welter, J.F.: Noninvasive evaluation of mechanical properties of agarose gels using ultrasound technology. BMES 2009
  79. Berilla, J. and Welter, J.F.: Time-constant based fluorescent oxygen sensor. BMES 2009
  80. Welter, J.F.; Pelyak, M.R.; Penick, K.J.; Solchaga, L.A.; and Goldberg, V.M.: Extracellular matrix deposition by chondrogenically differentiating human mesenchymal stem cells is enhanced by macromolecular crowding. OARSI World Congress on Osteoarthritis, Montréal, PQ Canada September 9-13, 2009
  81. Pelyak, M.; Penick, K.; Cheung, H.-M.; and Welter, J.: Accelerated MSC extracellular matrix deposition through dextran sulfate, polystyrene, and hyaluronic acid. MSC2009, August 17-19, 2009
  82. Chou, C.-L.; Rivera, A.L.; Welter, J.F.; and Baskaran, H.: Micrometer scale guidance of mesenchymal stem cells to form structurally oriented extracellular matrix. AICHE 2009 (Accepted)
  83. Berilla, J. and Welter, J.F.: Oxygen sensors for bioreactor monitoring. Proceedings of the 2009 Research ShowCASE, Case Western Reserve University, Cleveland, OH. 2009
  84. McKee, A.M.; Mansour, J.M.; and Welter, J.F.: Noninvasive evaluation of mechanical properties through the use of ultrasound technology. Proceedings of the 2009 Research ShowCASE, Case Western Reserve University, Cleveland, OH. 2009
  85. Pelyak, M.; Penick, K.; Cheung, H.M.; and Welter, J.F.: Accelerated MSC extracellular matrix deposition through dextran sulfate polystyrene, and hyaluronic acid. Proceedings of the 2009 Research ShowCASE, Case Western Reserve University, Cleveland, OH. 2009
  86. Welter, J.F.; Solchaga, L.A.; Leahy, P.; Penick, K.J.; Caplan, A.I.; Goldberg, V.M.: Gene expression patterns during chondrogenic differentiation of human MSCs. 55th Annual Meeting of the Orthopædic Research Society, Las Vegas, NV, February, 2009. 924.
  87. Pelyak, M.R.; Penick, K.J.; Berilla, J.A.; Solchaga, L.A.; and Welter, J.F.: Macromolecular crowding accelerates extracellular matrix deposition by differentiating MSCs. 55th Annual Meeting of the Orthopædic Research Society, Las Vegas, NV, February, 2009. 914.
  88. Valonen, P.K.; Moutos, F.T.; Kusanagi, A.; Moretti, M.; Diekman, B.O.; Welter, J.F.; Caplan, A.I.; Guilak, F.; and Freed, L.E.: In vitro generation of mechanically functional cartilage grafts based on adult human stem cells and 3D woven poly(?-caprolactone) scaffolds. 55th Annual Meeting of the Orthopædic Research Society, Las Vegas, NV, February, 2009. 934.
  89. Shao, Y.; Wang, L.; Welter, J.; Ballock, R.T.; Leiferman, E.; and Noonan, K.: Mechanical forces modulate indian hedgehog signaling in vitro and in vivo. 55th Annual Meeting of the Orthopædic Research Society, Las Vegas, NV, February, 2009. 993
  90. Welter, J.F.; Solchaga, L.A.; Leahy, P.; Penick, K.J.; Caplan, A.I.; Goldberg, V.M.: Database of gene expression patterns during chondrogenic differentiation of human MSCs. OARSI 2008 (accepted).
  91. Baskaran, H.; Kienitz, B. L.; Liang, W.-H.; Penick, K.; Welter, J. F.: Optimizing collagen-GAG scaffolds for tissue engineering applications. OARSI 2008 (accepted).
  92. Berilla, J and Welter, J.F.: Local thickness measurements in engineered cartilage using image analysis. BMES meeting 2008, (accepted)
  93. Berilla, J and Welter, J.F.: Image analysis algorithm for measuring local thickness in engineered cartilage. Proceedings of the 7th Annual meeting workshop of the Midwestern Tissue Engineering Consortium, April 11-12, University of Cincinnati, Cincinnati, OH. 2008:nnn
  94. Berilla, J and Welter, J.F.: Image analysis algorithm for measuring local thickness in engineered cartilage. Research ShowCase2008
  95. Shao, Y.Y.; Welter, J.F.; Wang, L.; and Ballock, R.T.: Response of growth plate chondrocytes to hydrostatic loading in vitro. 54th Annual Meeting of the Orthopaedic Research Society, San Francisco, CA, 638, March 2-5, 2008.
  96. Welter, J.F.; Baskaran, H.; Solchaga, L.A.; Penick, K.; and Berilla, J.: Aggregate formation dynamics as a biomarker for chondrogenic potential of mesenchymal stem cells. BMES 2007 P5.166
  97. Welter, J.F.; Baskaran, H.; Solchaga, L.A.; Penick, K.; and Berilla, J.: Aggregate formation dynamics as a biomarker for chondrogenic potential of mesenchymal stem cells. MSC2007, August 27-29, 2007:224
  98. Shao, Y.; Welter, J.; Wang, L.; and Ballock, T.: Hydrostatic loading of growth plate chondrocytes. ASBMR 2007 Journal of Bone and Mineral Research, 22S1:S156
  99. Berilla, J.; Penick, K.; Solchaga, L.; and Welter, J.: Timing of aggregate formation as a biomarker for chondrogenic potential. Proceedings of the 6th Annual meeting workshop of the Midwestern Tissue Engineering Consortium, April 20-21, 2007
  100. Penick, K., Solchaga, L.A.; and Welter, J.F.: A simplified aggregate culture system to assess chondrogenic potential. Proceedings of the 6th Annual meeting workshop of the Midwestern Tissue Engineering Consortium, April 20-21, 2007
  101. Berilla, J.; Penick, K.; Solchaga, L.; and Welter, J.: Timing of aggregate formation as a biomarker for chondrogenic potential. Proceedings of the 2007 Research ShowCASE, Case Western Reserve University, Cleveland, OH. 2007:102
  102. Penick, K., Solchaga, L.A.; and Welter, J.F.: A simplified aggregate culture system to assess chondrogenic potential. Proceedings of the 2007 Research ShowCASE, Case Western Reserve University, Cleveland, OH. 2007: 284
  103. Berilla, J.; Penick, K.; Solchaga, L.; and Welter, J.: Timing of aggregate formation as a biomarker for chondrogenic potential. Proceedings of the 2007 Research ShowCASE, Case Western Reserve University, Cleveland, OH. 2007:72
  104. Penick, K., Solchaga, L.A.; and Welter, J.F.: A simplified aggregate culture system to assess chondrogenic potential. Proceedings of the 2007 Research ShowCASE, Case Western Reserve University, Cleveland, OH. 2007
  105. Davood, V.; Welter, J.F.; Jackowe, D.J.; George, J.E.; Wang, J.Y. and Fisher, J.P.: Loading Rapid-Prototyped, Tissue-Engineered Poly(propylene fumarate) Scaffolds for Bioreactor Culturing. Proceedings of the 2007 Research ShowCASE, Case Western Reserve University, Cleveland, OH. 2007
  106. Solchaga, L.A.; Penick, K.J.; Caplan, A.C.; Goldberg, V.M.; and Welter, J.F.: Transforming growth factor-beta 1 modulates lineage progression of human mesenchymal stem cell-derived chondrocytes. Transactions of the Orthopædic Research Society, 2007, 32:1504
  107. Welter, J.F.; Solchaga, L.A.; Berilla, J.A.; Anderson, R.; Penick, K.J.; Vinson, A.; and Baskaran, H.: Measuring and modelling substrate mass-transport and consumption during human mesenchymal stem cell-based cartilage tissue engineering. Transactions of the Orthopædic Research Society, 2007, 32:494
  108. Welter, J.F.; Baskaran, H.; Solchaga, L.A.; and Goldberg, V.: Modelling substrate mass-transport during mesenchymal stem cell-based cartilage tissue engineering OARSI World Congress on Osteoarthritis Prague, Czech Republic December 7-10, 2006
  109. Solchaga, L.A.; Penick, K.; Caplan, A.I.; Goldberg, V.M.; and Welter, J.F.: Transforming growth factor-beta 1 modulates lineage progression of human mesenchymal stem cell-derived chondrocytes. OARSI World Congress on Osteoarthritis Prague, Czech Republic December 7-10, 2006
  110. Welter, J.F.; Anderson, R.; Penick, K.; Solchaga, L.A.; and Baskaran, H.: Substrate mass-transport modelling during MSC-based chondrogenesis Biomedical Engineering Society meeting, Chicago, IL, October 11 – October 14, 2006
  111. Anderson, R.; Baskaran, H.; Berilla, J.; Solchaga, L.; Penick, K.; and Welter, J.: Modeling mass-transport during maturation of MSC-based tissue engineered cartilage. Proceedings of the 2006 Research ShowCASE, Case Western Reserve University, Cleveland, OH. 2006:133
  112. Baskaran, H.; Kienitz, B.; and Welter, J.: Suspension centrifugation for optimizing lyophilized collagen-gag scaffolds for tissue engineering. Proceedings of the 2006 Research ShowCASE, Case Western Reserve University, Cleveland, OH. 2006:63
  113. Solchaga, L.; Penick, K.J.; Goldberg, V.M.; Caplan, A.I.; and Welter, J.F.: Regulation of hypertrophic differentiation of human mesenchymal stem cell-derived chondrocytes. Proceedings of the 2006 Research ShowCASE, Case Western Reserve University, Cleveland, OH. 2006:408
  114. Vinson, A.; Solchaga, L.; Penick, K.; Welter, J.F.; and Baskaran, H.: Assessment of mass transport limitations in mesenchymal stem cell-based spherical cartilage constructs. Proceedings of the 2006 Research ShowCASE, Case Western Reserve University, Cleveland, OH. 2006:42
  115. Anderson, R.W.; Baskaran, H.; Berilla, J.A.; Solchaga, L.A.; Penick, K.J.; and Welter, J.F.: Modeling substrate mass transport during the growth of an MSC-based cartilage construct. Proceedings of the 6th symposium of the International Cartilage Repair Society, San Diego, CA, 8 – 11 January 2006: P3-40
  116. Solchaga, L.A.; Penick, K.J.; Goldberg, V.M.; Caplan, A.I.; Welter, J.F.: Regulation of lineage progression of human mesenchymal stem cell-derived chondrocytes. Proceedings of the 6th symposium of the International Cartilage Repair Society, San Diego, CA, 8 – 11 January 2006: P4-51
  117. Berilla, J.A.; Solchaga, L.A.; Baskaran, H.; and Welter, J.F.: A modular bioreactor optimized for cartilage tissue engineering. Biomedical Engineering Society meeting, Baltimore, MD, September 28 – October 1, 2005, 277:15
  118. Berilla, J.A.; Solchaga, L.A.; Penick, K.; Baskaran, H.; and Welter, J.F.: A modular bioreactor system for cartilage tissue engineering. Proceedings of the Arthritis Research Conference, Atlanta, GA. 2005
  119. Solchaga, L.A.; Penick, K.; Porter, J.D.; Goldberg, V.M.; Caplan, A.I.; Welter, J.F.: FGF-2 enhances the mitotic and chondrogenic potentials of human adult bone marrow-derived mesenchymal stem cells. Proceedings of the Arthritis Research Conference, Atlanta, GA. 2005
  120. Baskaran, H.; Berilla, J.; Solchaga, L.; and Welter, J.F.: Mesenchymal stem cell-based cartilage tissue engineering. Proceedings of the Arthritis Research Conference, Atlanta, GA. 2005
  121. Burton, L.; Penick, K.; Welter, J.F.; Caplan, A.I.; Goldberg, V.M.; and Solchaga, L.A.: Fibroblast growth factor-2 enhances the chondrogenic differentiation of adult mesenchymal stem cells. Proceedings of the 2005 Research ShowCASE, Case Western Reserve University, Cleveland, OH. 2005:169
  122. Berilla, J.; Solchaga, L.A.; Penick, K.; Baskaran, H.; and Welter, J.F.: A modular bioreactor system for cartilage tissue engineering Proceedings of the 2005 Research ShowCASE, Case Western Reserve University, Cleveland, OH. 2005:324
  123. Baskaran, H.; Berilla, J.; Solchaga, L.; and Welter, J.F.: Mesenchymal stem cell-based cartilage tissue engineering Proceedings of the 2005 Research ShowCASE, Case Western Reserve University, Cleveland, OH. 2005:50
  124. Welter, J.F.; Solchaga, L.A.; Penick, K.; Baskaran, H.; Goldberg, V.M.; Caplan, A.I.; and Berilla, J.A.: A modular bioreactor system for cartilage tissue engineering. Transactions of the Orthopædic Research Society, 2005, 30(2):1771
  125. Wenger, R.; Welter, J.F.; Hans, M.G.; Malemud, C.J.: Hydrostatic pressure increases apoptosis in tissue-engineered cartilage-constructs. Osteoarthritis Cartilage 12 Supplement B, S73, 2004
  126. Baskaran, H.; Solchaga, L.; Berilla, J.; and Welter, J.: Mesenchymal stem cell based cartilage tissue engineering. American Institute of Chemical Engineers meeting, Austin, TX, November 7-12, 2004:75c
  127. Baskaran, H.; Solchaga, L.; Berilla, J.; and Welter, J.: Transport considerations in mesenchymal stem cell-based cartilage tissue engineering. Biomedical Engineering Society meeting, Philadelphia, PA, October 13-16, 2004, 971:44
  128. Welter, J.; Baskaran, H.; Berilla, J.; Penick, K.; Goldberg, V.; Mansour, J.; Caplan, A.; and Solchaga, L.: Expansion and differentiation environment modulates chondrogenesis in large tissue engineered constructs. Biomedical Engineering Society meeting, Philadelphia, PA October 13-16, 2004972:44
  129. Welter, J.; Baskaran, H.; Berilla, J.; Penick, K.; Goldberg, V.; Mansour, J.; Caplan, A.; and Solchaga, L.: Enhanced chondrogenesis in large tissue engineered constructs by modulation of growth and differentiation conditions. Proceedings of the 5th symposium of the International Cartilage Repair Society, Ghent, Belgium, May 26 – 29, 2004:625
  130. Baskaran, H.; Solchaga, L.; Berilla, J.; and Welter, J.: Assessment of mass transport limitations during cartilage tissue engineering. Proceedings of the 5th symposium of the International Cartilage Repair Society, Ghent, Belgium, May 26 – 29, 2004:653
  131. Baskaran, H.; Solchaga, L.A.; Berilla, J.; and Welter, J.F.: Assessment of mass transport limitations during cartilage tissue engineering. Proceedings of the 2004 Research ShowCASE, Case Western Reserve University, Cleveland, OH. 2004:212
  132. Solchaga, L.A.; Goldberg, V.M.; Mishra, R.; Caplan, A.I.; Penick, K.J.; and Welter, J.F.: FGF-2 enhances the mitotic and chondrogenic potentials of human adult mesenchymal stem cells. Proceedings of the 2004 Research ShowCASE, Case Western Reserve University, Cleveland, OH. 2004:447
  133. Welter, J.F.; Baskaran, H.; Berilla, J.; Penick, K.; Goldberg, V.M.; Mansour, J.; Caplan, A.I.; and Solchaga, L.: Modulation of growth and differentiation conditions enhances chondrogenesis in large tissue engineered constructs. Proceedings of the 2004 Research ShowCASE, Case Western Reserve University, Cleveland, OH. 2004:448
  134. Welter, J.F.; Baskaran, H.; Berilla, J.; Penick, K.; Mansour, J.; Caplan, A.I.; and Solchaga, L.: Modulation of growth and differentiation conditions enhances chondrogenesis in large tissue engineered constructs. Transactions of the Orthopædic Research Society, 2004, 29(2):719
  135. Baskaran, H.; Solchaga, L.A.; Berilla, J.; and Welter, J.F.: Assessment of mass transport limitations during cartilage tissue engineering. Transactions of the Orthopædic Research Society, 2004, 29(2):721
  136. Solchaga, L.A.; Goldberg, V.M.; Mishra, R.; Caplan, A.I.; and Welter, J.F.: FGF-2 modifies the gene expression profile of bone marrow-derived human mesenchymal stem cells. Transactions of the Orthopædic Research Society, 2004, 29(2):777
  137. Welter, J.F.; Penick, K.; Berilla, J.; Caplan, A.I.; Goldberg, V.M.; and Solchaga, L.A.: MSC-based tissue engineered cartilage: Effects of construct assembly method and perfusion rates. Proceedings of the Arthritis Research Conference, Keystone, CO. 2003:71
  138. Baskaran, H.; Solchaga, L.A.; Penick, K.; Berilla, J.; and Welter, J.F.: Substrate mass transport in tissue engineered cartilage. Proceedings of the Arthritis Research Conference, Keystone, CO. 2003:70
  139. Welter, J.F.; Solchaga, L.; and Berilla, J.: Design of a modular bioreactor system. Proceedings of the 2003 Research ShowCASE, Case Western Reserve University, Cleveland, OH. 2003:69
  140. Penick, K.; Berilla, J.; Solchaga, L.; and Welter, J.F.: On the use of Delrin® (acetal) in tissue culture. Proceedings of the 2003 Research ShowCASE, Case Western Reserve University, Cleveland, OH. 2003:41
  141. Baskaran, H.; Solchaga, L.A.; Penick, K.; Berilla, J.; and Welter, J.F.: Substrate mass transport in tissue engineered cartilage. Proceedings of the 2003 Research ShowCASE, Case Western Reserve University, Cleveland, OH. 2003:67
  142. Berilla, J.; Solchaga, L.; and Welter, J.F.: A multichannel fiberoptic spectrophotometer for monitoring bioreactor medium pH. Proceedings of the 2003 Research ShowCASE, Case Western Reserve University, Cleveland, OH. 2003:247
  143. Malemud, C.; Islam, N.; Haqqi, T.; Jepsen, K.; Kraay, M.; Welter, J.F.: and Goldberg, V.: Role of apoptosis in arthritis. Proceedings of the 2003 Research ShowCASE, Case Western Reserve University, Cleveland, OH. 2003:24
  144. Solchaga, L.A.; Goldberg, V.M.; Mansour, J.; Caplan, A.I.; and Welter, J.F.: Cartilage tissue engineering: In vitro generation of large cartilaginous constructs. Transactions of the Orthopædic Research Society, 2003, 28(2):944
  145. Welter, J.F.; Tognana, E.; Goldberg, V.M.; Caplan, A.I.; and Solchaga, L.A.: Assembly of large cell-scaffold composites for cartilage tissue engineering. Transactions of the Orthopædic Research Society, 2003, 28(2):949
  146. Solchaga, L.A.; Tognana, E.; Goldberg, V.M.; Caplan, A.I.; and Welter, J.F.: Tissue engineered cartilage implants: in vitro chondrogenic pre-conditioning. Proceedings of the 4th symposium of the International Cartilage Repair Society, Toronto / CA, 15 – 18 June 2002:271
  147. Welter, J.F.; Tognana, E.; Mansour, J.; Goldberg, V.M.; Caplan, A.I.; and Solchaga, L.A.: Tissue engineered cartilage implants: in vitro chondrogenic preconditioning. Proceedings of the 2nd Annual workshop of the Midwestern Tissue Engineering Consortium, 2002:21
  148. Solchaga, L.; Tognana, E.; Goldberg, V.M.; Caplan, A.I.; and Welter, J.F.: Tissue engineered cartilage implants: optimizing construct assembly. Transactions of the Orthopædic Research Society, 2002, 27(1):483
  149. Welter, J.F.; Pradhan, S.; Tsurel, S.; and Berilla, J.: Modulation of the c-fos promoter activity by brief low amplitude strains: a role for ets transcription factors? Transactions of the Orthopædic Research Society, 2002, 27(2):522
  150. Tsurel, S.; Pradhan, S.; Berilla, J.; and Welter, J.F.: Response of osteoblasts to brief, low amplitude strains: modulation of c-fos promoter activity. Israel Orthopaedic Association, Tel Aviv, December 4-5, 2001. J. Bone Joint Surg., 84-B(Supll. III):316-317
  151. Solchaga, L.A.; Tognana, E.; and Welter, J.F.: Tissue engineered cartilage implants: optimizing construct assembly. Orthopædic Research Day, Case Western Reserve University, June 2001
  152. Berilla, J. and Welter, J.F.: Development of a Shear Sensor for Cell Culture Applications. Orthopædic Research Day, Case Western Reserve University, June 2001
  153. Pradhan, S.; Berilla, J.; Tsurel, S.; and Welter, J.F.: Response of osteoblasts to brief, low amplitude strains: Modulation of c-fos promoter activity. Orthopædic Research Day, Case Western Reserve University, June 2001
  154. Malemud, C.J.; Haqqi, T.M.; Jepsen, K.J.; Islam, N.; Kraay, M.; Welter, J.; and Goldberg, V.M.: Induction of apoptosis in human chondrocytes by hydrostatic pressure. Osteoarthritis and Cartilage 2001, 9(Supplement B):S8
  155. Pradhan, S.; Tsurel, S.; Berilla, J.; and Welter, J.F.: Response of the c-fos promoter to brief low amplitude strains in osteoblasts: a role for ets transcription factors? ASBMR 2001 J. Bone Miner. Res. 2001, 16(S1):S361
  156. Balasubramanian, S.; Agarwal, C.; Efimova, T.; Dubyak, G.; Banks, E.B.; Welter, J.F.; and Eckert. R.L.: Thapsigargin suppresses differentiation-dependent human involucrin promoter activity by reducing CCAAT/enhancer-binding protein – DNA binding. 62nd Annual Meeting of the Society for Investigative Dermatology, Washington, DC, May, 2001
  157. Tsurel, S. and Welter, J.F.: Physiological levels of mechanical strain modulate osteoblast differentiation in vitro. Orthopaedic Research Day, Case Western Reserve University, January 2000
  158. Islam, N.; Islam, S.; Haqqi, T.; and Welter, J.F.: EGCG inhibits chondrocyte apoptosis. Orthopædic Research Day, Case Western Reserve University, January 2000
  159. Welter, J.F.; Islam, N.; Islam, S.; and Haqqi, T.M.: EGCG – a constituent of green tea – inhibits chondrocyte apoptosis. Transactions of the Orthopædic Research Society 2000, 25(2):907
  160. Agarwal, C.; Effimova, T.; Welter, J.F.; Crish, J.F.; and Eckert, R.L.: CCAAT/Enhancer binding proteins – required regulators of human involucrin promoter activity. Journal of Investigative Dermatology 1999, 112(4):549
  161. Effimova, T.; LaCelle, P.T.; Welter, J.F.; and Eckert, R.L.: Regulation of human involucrin promoter activity via a specific MAPK signal transduction cascade. Journal of Investigative Dermatology 1999, 112(4):549
  162. Effimova, T.; LaCelle, P.T.; Welter, J.F.; and Eckert, R.L.: Regulation of human involucrin promoter activity by a PKC, RAS, MEKK1, MEK3, p38/RK, AP1 signal transduction pathway. Proceedings of the AACR 1999, 40:364
  163. Tsurel, S.; Goldberg, V.M.; and Welter, J.F.: The response of human mesenchymal stem cells to mechanical strains changes as a function of differentiation state. Transactions of the Orthopædic Research Society, 1999, 24(2):628
  164. Banks, E.B.; Crish, J.F.; Welter, J.F.; and Eckert, R.L.: Characterization of human involucrin promoter distal regulatory region transcriptional activator elements – a role for SP1 and AP1 binding sites. Journal of Investigative Dermatology 1998, 110(4):604
  165. Efimova, T.; Banks, E.B.; LaCelle, P.T.; Welter, J.F.; and Eckert, R.L.: Regulation of human involucrin promoter activity by a protein kinase C, Ras, MEKK, and Activator Protein-1 signal transduction pathway. Journal of Investigative Dermatology 1998, 110(4):604
  166. Welter, J.F.; Agarwal, C.; Efimova, T.; and Eckert, R.L.: The human involucrin promoter proximal regulatory region – a role for C/EBP, AP1, ets, and AP2 binding sites. Journal of Investigative Dermatology 1998, 110(4):603
  167. Welter, J.F. and Eckert, R.L.: Functional characterization of the human involucrin proximal promoter regulatory region – Effects of CAAT enhancer binding protein, activator protein – 1, ETS factors and activator protein – 2. Journal of Investigative Dermatology 1997, 108(4):630
  168. Welter, J.F.; Robinson, N.A.; Bright, G.R.; and Eckert, R.L.: Immunocytochemical localization of AP1 family transcription factors in normal human keratinocytes cultured under serum free conditions. Journal of Investigative Dermatology 1997, 108(4):630
  169. Robinson, N.A.; Lapic, S.; Welter, J.F.; and Eckert, R.L.: S100c, s100a10, annexin I, desmosomal proteins, sprs, plasminogen activator inhibitor – 2, and involucrin are components of the cornified envelope of cultured human epidermal keratinocytes. Journal of Investigative Dermatology 1997, 108(4):552
  170. Welter, J.F.; Gali, H.U.; Crish, J.F.; and Eckert, R.L.: Regulation of the human involucrin promoter by POU domain proteins. Journal of Investigative Dermatology 1996, 106(4):907
  171. Banks, E.B.; Crish, J.F.; Welter, J.F.; and Eckert, R.L.: Combinatorial regulation of human involucrin promoter activity by modulator, silencer and enhancer elements. Journal of Investigative Dermatology 1996, 106(4):838
  172. Welter, J.F. and Eckert, R.L.: Expression of activator protein-1 (AP-1) family members in the human epidermis and in cultured keratinocytes. Journal of Investigative Dermatology 1995, 104(4):674
  173. Welter, J.F.; Crish, J.F.; Agarwal C.; and Eckert R.L.: Regulation of human involucrin promoter function by activator protein-1 (jun/fos) and phorbol myristate acetate. Journal of Investigative Dermatology 1994, 102(4):577
  174. Brown, K.L.B. and Welter, J.F.: A comparison of vascularized and conventional bone grafts for bridging large bone defects. In: Proceedings of the Fourth International Symposium on Limb Salvage in Musculoskeletal Oncology. Springer Verlag
  175. Welter, J.F. and Brown, K.L.B.: A comparison of free vascularized and conventional fibular grafts for large defects in weight bearing bones. In: Aebi, M. and Regazzoni, P. (eds) Proceedings of the First International Symposium on Bone Transplantation: 1989, pp. 86 – 87. Springer Verlag
  176. Welter, J.F. and Brown, K.L.B.: A comparison of free vascularized and conventional fibular grafts for large defects in weight bearing bones. Orthopædic Transactions 1987, 11(2):291 – 292
  177. Welter, J.F.; Kornacki, J.B.; and Brown, K.L.B.: A comparison of free vascularized and conventional fibular grafts for large defects in weight bearing bones. Transactions of the Orthopædic Research Society, 1987, 22(1):115
  178. Brown, K.L.B.; Kornacki, J.B.; Welter, J.F.; Poole, A.R.; and Cruess, R.L.: The effects of weightbearing on the growth of heterotopically transplanted free vascularized epiphyseal grafts in dogs. Orthopædic Transactions 1986, 10(2):241 – 242
  179. Brown, K.L.B.; Kornacki, J.B.; Welter, J.F.; and Cruess, R.L.: The effects of weight bearing on the growth of heterotopically transplanted free vascularized epiphysial grafts in dogs. Transactions of the Orthopædic Research Society, 1986, 21(1):52

 

Invited Presentations:

  1. Combined sliding shear and ultrasound evaluation demonstration. CTTE – 2019 “Cell-Based Therapies and Tissue Engineering” short course, Case Western Reserve University, Cleveland, OH, May 22, 2019.
  2. Joint flexion bioreactor demonstration. CTTE – 2019 “Cell-Based Therapies and Tissue Engineering” short course, Case Western Reserve University, Cleveland, OH, May 22, 2019.
  3. Combined sliding shear and ultrasound evaluation demonstration. CTTE – 2018 “Cell-Based Therapies and Tissue Engineering” short course, Case Western Reserve University, Cleveland, OH, May 23, 2018.
  4. Ultrasound applications in cartilage. Skeletal Research Center seminar series, Case Western Reserve University, Cleveland, OH, November 7, 2016
  5. Sounds Hard. Ultrasound applications in cartilage. Skeletal Research Center seminar series, Case Western Reserve University, Cleveland, OH, December 8, 2014.
  6. Cartilage Tissue Engineering. EBME 325 guest lecture, Case Western Reserve University, Cleveland, OH, November 5, 2012.
  7. Poking around in the viscosupplementation morass. Skeletal Research Center seminar series, Case Western Reserve University, Cleveland, OH, April 16, 2012.
  8. Canine and Human Mesenchymal Stem Cells, Growth Factors, Bioreactors, and Animal Model Studies. External Advisory Board and Co-Investigators meeting of NIH Grant R01-DE013740, Strength and Resorption of Biodegradable Skull Implants. July 21, 2011
  9. Intra-articular delivery of injectable sustained-release drug formulations. NCRM Retreat, November 14, 2011
  10. X marks the spot. Spatial and temporal distribution of Type X collagen in engineered cartilage. MSCs Skeletal Research Center seminar series, Case Western Reserve University, Cleveland, OH, November 15, 2010
  11. Canine Mesenchymal Stem Cells, Growth Factors, Bioreactors, and Toxicity. External Advisory Board and Co-Investigators meeting of NIH Grant R01-DE013740, Strength and Resorption of Biodegradable Skull Implants. June 2, 2010
  12. Crowding MSCs Skeletal Research Center seminar series, Case Western Reserve University, Cleveland, OH, February 1, 2010.
  13. Cartilage tissue engineering. EBME 325 guest lecture, Case Western Reserve University, Cleveland, OH, November 30, 2009
  14. Optimizing MSC differentiation; CTTE-2009 “Cell-Based Therapies and Tissue Engineering” short course, Case Western Reserve University, Cleveland, OH, May 25, 2009
  15. How Thick Is That? Skeletal Research Center seminar series, Case Western Reserve University, Cleveland, OH, March 23, 2009
  16. Bioreactors for Cartilage Tissue Engineering; CTTE-2008 “Cell-Based Therapies and Tissue Engineering” short course, Case Western Reserve University, Cleveland, OH, May 26, 2008
  17. Optimizing MSC differentiation; CTTE-2008 “Cell-Based Therapies and Tissue Engineering” short course, Case Western Reserve University, Cleveland, OH, May 26, 2008
  18. Case study: Cartilage tissue engineering. EBME 325 guest lecture, Case Western Reserve University, Cleveland, OH, November 15, 2007
  19. Probing MSC differentiation. Skeletal Research Center seminar series, Case Western Reserve University, Cleveland, OH, October 29, 2007
  20. Heavy breathers: oxygen consumption in cartilage tissue engineering. Case Study: Cartilage Tissue engineering.
  21. Case study: Cartilage tissue engineering. EBME 325 guest lecture, Case Western Reserve University, Cleveland, OH, November 9, 2006
  22. Bioreactors for mesenchymal stem cell differentiation; CTTE-2006 Cell-Based Therapies and Tissue Engineering short course, Case Western Reserve University, Cleveland, OH, May 26, 2006
  23. Cartilage tissue engineering. Department of Biology seminar series. Case Western Reserve University, Cleveland, OH. May 4, 2006
  24. Bioreactors for mesenchymal stem cell differentiation; CTTE-2005 Cell-Based Therapies and Tissue Engineering short course, Case Western Reserve University, Cleveland, OH, June 1, 2005
  25. Surface characteristics of trabecular metal bone implants. Orthopædic and Related Research Seminar series, Case Western Reserve University, Cleveland, OH, May 26, 2005
  26. Surface characteristics of bone implants. Skeletal Research Center seminar series, Case Western Reserve University, Cleveland, OH, November 29, 2004
  27. More cartilage tissue engineering – Design of a hydrostatic loading bioreactor. Skeletal Research Center seminar series, Case Western Reserve University, Cleveland, OH, March 15, 2004
  28. Cartilage tissue engineering. Skeletal Research Center seminar series. Case Western Reserve University, Cleveland, OH. March 10, 2003
  29. Cartilage tissue engineering. Orthopædic grand rounds, Case Western Reserve University and University Hospitals of Cleveland, Cleveland, OH. February 22, 2003.
  30. Cartilage tissue engineering. Issues and approaches. CWRU/CCF musculoskeletal research seminar series. Case Western Reserve University, Cleveland, OH, December 12, 2002
  31. Cartilage tissue engineering: Presented to the Arthritis Foundation Board of Trustees, Cleveland, OH, October 29, 2002